[PDF] Top 20 Sulforaphane suppresses TNF-α-mediated activation of NF-kB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3
Has 10000 "Sulforaphane suppresses TNF-α-mediated activation of NF-kB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3" found on our website. Below are the top 20 most common "Sulforaphane suppresses TNF-α-mediated activation of NF-kB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3".
Sulforaphane suppresses TNF-α-mediated activation of NF-kB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3
... 이 논문에서는 tumor necrosis factor-α (TNF- α) 와 sub-toxic 농도의 SFN을 함께 처리하였을 때, TNF-α-resistant 인체 백혈병 세포주인 THP-1, HL60, U937과 K562에 세포사멸을 효과적으로 유도함을 확인하였다. 또한, SFN의 처리는 TNF-α 에 의해 유도되는 NF-κB의 활성을 ... See full document
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Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells
... generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer ...Reactive ... See full document
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A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells
... systems and inhibits glucose uptake in tumor ...vivo, and constrains tumor growth through the inhibition of 12-O-tetradecanoylphorbol- 13-acetate-induced cyclooxygenase-2 ...induction ... See full document
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<i>Juniperus chinensis</i> extract induces apoptosis via reaction oxygen species (ROS) generation in human pancreatic cancer cell lines
... half of patients with this cancer have very few symptoms at the early stages, allowing the development of distant metastases and resistance to cancer ...viability and migration activity ... See full document
6
Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt
... effect of curcumin on the activation of the apoptotic pathway in human renal Caki ...Treatment of Caki cells with 50 mM curcumin resulted in the activation of caspase ... See full document
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2',3'-dimethoxyflavanone induces apoptosis accompanied by caspase-8 activation mediated by ubiquitination in breast cancer stem-like cells (BCSCs)
... 40% of all breast cancer patients have tumor relapse in conventional ...under-treatment of drugs, local sites of tumor growth missed during doing surgery or the prior development of ... See full document
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ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells
... EGFR and ERBB2 targeting, the genetic inhibition of ERBB3 results in anti-tumorigenic in HCT116 colon cancer cells harboring constitutively active KRAS and PIK3CA ...arrest and ... See full document
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Caveolin-1 is involved in reactive oxygen species-induced SHP-2 activation in astrocytes
... evidence of a novel signaling pathway implicating caveolin-1 as a positive regulator of H 2 O 2 -induced SHP-2/ERK signaling in ...presence of caveolin-1 and its expression level were critical ... See full document
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(-)-Epigallocatechin gallate (EGCG) induces apoptosis in osteoclasts differentiated from RAW 264.7 cells via caspase activation
... 연세대학교 대학원 치의학과 (지도 최성호 교수) 윤 정 호 치조골 흡수는 치주질환의 특징적인 양상이며, 골의 무기질과 유기질의 제거가 일어나는데, 이러한 과정에는 파골세포가 주로 관여한다. (-)-epigallocatechin gallate (EGCG)는 녹차의 주된 성분으로서, 파골세포의 apoptosis를 유도하고 다양한 형태의 종양 세포에서 caspase ... See full document
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Miconazole induces autophagic death in glioblastoma cells via reactive oxygen species-mediated endoplasmic reticulum stress
... ROS‑ and ER stress‑inducing effects of miconazole in relation to autophagic cell ...quantity of ROS species in the cells. (B) Levels of LC3‑I and LC3‑II proteins in ... See full document
9
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
... implications of our studies will depend on whether or not curcumin can be given safely to humans at doses high enough to achieve pharmacologically active ...trials of oral curcumin cannot be utilized ... See full document
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RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis
... to activation of PLC␥1. Indeed, inhibition of RANKL- mediated ROS generation inhibits activation of PLC ␥1 ...placing activation of PLC ␥1 downstream of ROS ... See full document
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RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis
... to activation of PLC␥1. Indeed, inhibition of RANKL- mediated ROS generation inhibits activation of PLC ␥1 ...placing activation of PLC ␥1 downstream of ROS ... See full document
10
Angelicin potentiates TRAIL-induced apoptosis in renal carcinoma Caki cells through activation of caspase 3 and down-regulation of c-FLIP expression
... anti-inflammatory and anti-tumor activity. In the present study, the effect of angelicin in enhancing tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptotic cell death was ... See full document
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Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L)
... Death and Disease (2014) 5, e1063; ...psychosis and schizophrenia. 1,2 Thioridazine also has antimicrobial activity and is thus used as a treatment against drug-resistant organisms, such as ... See full document
9
Mitochondrial respiratory defects induces claudin 1 expression via ROS-mediated HSF1 activation
... 의해서 activation 된 band 인지 확인하기 위해 lambda phosphatase 처리와 S326 잔기에 인산화된 HSF1 항체로 shift 된 band 가 HSF1 의 phosphorylation 에 의해서 activation 된 band 임을 확인 ...에 activation 에 의해 조절된 것임을 알 수 ... See full document
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TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells
... assay and CAM assay. In the mouse Matrigel plug assay, the ability of TRANCE to promote neovessel formation was comparable with that of the well established angiogenic factor ...stimulation of ... See full document
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Trifolium pratense induces apoptosis through caspase pathway in FaDu human hypopharynx squamous carcinoma cells
... 의 cleavage 현상을 확인하였다. 또, 내인성 세포사멸 인자인 Bcl-2 와 Bax의 단백발현을 확인한 결과, anti-apoptotic 분자인 Bcl-2의 단 백발현이 농도-의존적으로 감소하였으며, pro-apoptotic 분자인 Bax 의 단백발현이 증가함을 확인하였다. MeTP에 의한 세포사멸 기전은 유방암 세포주와 다형교모세포종의 세포사멸 기전과 일치하는 것으로, Khazaei ... See full document
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Ionizing radiation induces PI3K-dependent JNK activation for amplifying mitochondrial dysfunction in human cervical cancer cells
... one of the most commonly used treatments for a wide variety of ...Exposure of cells to ionizing radiation results in the simultaneous activation or down regulation of multiple signaling ... See full document
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TRAIL promotes caspase-dependent pro-inflammatory responses via PKCδ activation by vascular smooth muscle cells
... roles of caspases by cleavage of unidentified intermediates so as to transduce non- apoptotic ...that caspase-8 is involved in the cleavage of IkB between Asp 31 and Ser, 32 leading to ... See full document
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