drug resistance
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Hepatitis C Virus and Antiviral Drug Resistance
... antiviral drug resistance are being reported and the retreatment of the patients who have failed in the prior antiviral treatments is the issue that has to be immediately ...
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Drug Resistance Patterns of Multidrug- and Extensively Drug-Resistant Tuberculosis in Korea: Amplification of Resistance to Oral Second-line Drugs
... the drug resistance patterns of multidrug-resistant and extensively drug-resistant tuberculosis (TB) and the difference of drug resistance among various set- tings for health care in ...
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The Drug Resistance Profile of Group Strains from Korea
... Methods: We performed drug susceptibility testing for a total of 404 M. abscessus clinical strains. Subspecies were differentiated by molecular biological methods and examined for mutations in drug ...
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Comparison of Clinical Characteristics between Pulmonary Tuberculosis Patients with Extensively Drug-resistance and Multi-drug Resistance at National Medical Center in Korea
... This study examined the clinical differences between pulmonary TB patients with extensively drug resistance (XDR) and multi-drug resistance (MDR) at the National Medical Center[r] ...
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Mutations in extensively drug-resistant Mycobacterium tuberculosis that do not code for known drug-resistance mechanisms
... other drug-resistant strains ...to drug-resistant ...that drug-resistant ...known resistance-associated genes can provide drug-resistance without attenuation (such as katG315 ...
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Drug Resistance Rates of at a PrivateReferral Center in Korea
... the drug resis- tance of ...the drug susceptibility test was not recommended to new cases by the NTP program in Korea until recent ...had drug susceptibility test results could over- estimate the ...
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Healthcare-Associated Urinary Tract Infection: Multi Drug Resistance and Risk Factors
... Keywords: Cross infection; Multiple drug resistance; Urinary tract infections Copyright 2018, Korean Association of Urogenital Tract Infection and Inflammation. All rights reserved. This is an open access ...
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Drug Resistance and R-Plasmid Profile of Shigella Isolated in 1986-1988
... Drug resistance patterns of isolated strains were found as the highest resistance to ampicillin (98%) in 1986, to tetracycline (98%) in 1987, to tetracycline (100%) in 1988, all strain[r] ...
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Phenotypic and Genotypic Analysis of Anti-Tuberculosis Drug Resistance in Isolates in Myanmar
... the resistance in this ...common drug resistance-mutation pattern found in the present study suggested that genotypic DST should be more widely used as a routine test to determine drug ...
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Machine Learning to Improve the Effectiveness of ANRS in Predicting HIV Drug Resistance
... Table 4 shows the positive predictive value (PPV) and negative predictive value (NPV) of all the PR ARVs used in the study. A Z-score >1.98 was obtained when the new ANRS rules where used indicating there is a statically ...
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Analysis of Integron-Associated Multi-Drug Resistance of Acinetobacter baumannii Isolated in Korea
... extended resistance to most β-lactams including imipenem, kanamycin, gentamicin, tobramycin, and cephalosporins of the third and fourth generations, and produced metallo-β-lactamase (MBL) of IMP-1 type which is ...
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Nuclear factor (erythroid-derived 2)-like 2 regulates drug resistance in pancreatic cancer cells
... that drug resistance in pancreatic cancer results, in part, from elevated levels of Nrf2 and its target ...Nrf2-related drug resistance (data not ...
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Identification of innate drug resistance against raf inhibitors in patients with papillary thyroid cancer
... In contrast to the high response rate of metastatic melanomas to BRAF inhibitors, RAF or MEK inhibitors show limited efficacy in RAI-refractory thyroid cancer and thyroid cancer cell lines harboring BRAF V600E . 24-26 ...
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KRDS: a web server for evaluating drug resistance mutations in kinases by molecular docking
... However, drug resistance has emerged as a major obstacle to cancer ...therapy. Resistance to drugs has various underlying mechanisms, including the acquisition of mutations at drug binding ...
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Activation of the Met kinase confers acquired drug resistance in FGFR-targeted lung cancer therapy
... acquired resistance to targeted therapies in various types of cancers by maintaining the signaling of key downstream ...acquired resistance to an FGFR-TKIs and found Met overexpression in two different ...
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Constitutive Expression of MAP Kinase Phosphatase-1 Confers Multi-drug Resistance in Human Glioblastoma Cells
... We found that MKP-1 is highly expressed in human GBMs and trans- formed GBM cell lines in the absence of external stimulation. We also found that high levels of MKP-1 are responsible for drug-resistance in ...
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Additional Drug Resistance Patterns among Multidrug-Resistant Tuberculosis Patients in Korea: Implications for Regimen Design
... additional resistance during treatment using the conventional ...of drug resistance and high-re- source settings, individually tailored regimens based on the re- sistance patterns may be more ...
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Notch1 Expression Regulates the Invasiveness and Drug Resistance in Sphere-forming NCI-H460 Cancer Cells
... Keywords Cancer stem cells, Notch signaling, Slug, Drug resistance, Invasion 서 론 (Introduction) 폐암치료를 위해 최근 효과적인 암치료제들이 개발되어 임상 에 사용되고 있으나 암전이, 재발, 항암치료 내성은 여전히 풀어 야 할 숙제로 남아 있다. 1) 암줄기세포(cancer stem cell)는 ...
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Comparison of Antimicrobial Resistance and Multi-Drug Resistance Patterns of Escherichia coli Isolated from Aquatic Organisms Off the West Coast of South Korea
... Antimicrobial resistance patterns of Escherichia coli were ...highest resistance to ampicillin ...dime resistance was observed in strains isolated from short neck and hard clams, whereas gentamicin ...
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Droplet-based microtumor model to assess cell-ECM interactions and drug resistance of gastric cancer cells
... and drug resist- ances of different types of gastric cancer, using the AGS (intestinal type) and Hs746T (diffuse type) cell ...the drug resistance-related molecules were significantly up-regulated in ...
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