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Comparison of changes in nutritional status, pancreatic function and quality of life according to gender after pancreatectomy

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AHBPSAnnals of Hepato-Biliary-Pancreatic Surgery

www.ahbps.org S161

Comparison of changes in nutritional status, pancreatic function and quality of life according to

gender after pancreatectomy

Yong Chan SHIN, Sung Won JUNG*

Department of Surgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea

BP-PP-2-7

Introduction: To compare and analyze changes in nutritional status, pancreatic function and quality of life (QoL) according to gender after pancreatectomy.

Methods: Patients undergoing pancreaticoduodenectomy (PD) or distal pancreatectomy (DP) between 2007 and 2013 were included.

Data on relative body weight (RBW); triceps skinfold thickness (TSFT); body mass index (BMI); serum protein, albumin, transferrin, fasting blood glucose, postprandial 2-h glucose, and stool elastase levels; and QoL questionnaire scores were collected serially for 5 years.

Results: RBW, TSFT, and BMI showed similar patterns of change between male and female patients. Biochemical parameters recov- ered to preoperative values 3 months after surgery in both groups. There was no significant difference in the incidence of diabetes mel- litus or impaired fasting glucose between men and women during the follow-up period except for 6 months after surgery. Stool elastase levels showed similar patterns in the two groups from 12 months after surgery. Male patients scored relatively higher than female pa- tients on the EORTC QLQ-C30 questionnaire. There was a significant difference in global health status/QoL between the two groups at 6 and 12 months after surgery and female gender was an independent risk factor for low global health status/QoL in a multivariate analysis. In EORTC QLQ-PAN26 questionnaire, female patients showed a relatively slow decrease in symptom scale scores than male patients.

Conclusions: Although female patients showed better nutritional status than males after pancreatectomy, the rate of complaining of functional difficulties and surgery-related symptoms was relatively higher than males in quality of life analysis.

pISSN: 2508-5778ㆍeISSN: 2508-5859

Ann Hepatobiliary Pancreat Surg 2021;25 Suppl 1:S161 https://doi.org/10.14701/ahbps.BP-PP-2-7

Corresponding Author: Sung Won JUNG (sungwon94@naver.com) Presenter: Yong Chan SHIN (ycshindr@gmail.com)

Copyright Ⓒ The Korean Association of Hepato-Biliary-Pancreatic Surgery

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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