Good Responders in Primary Chemotherapy on the Breast Cancer

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Good Responders in Primary Chemotherapy on the Breast Cancer

= Abstract =

Good Responders in Primary Chemotherapy on the Breast Cancer Eil Sung Chang. M.D., Jang Yong Kim, M.D. and Hae Duck Park, M.D.

Department of Surgery, College of Medicine, Chungnam National University

The therapeutic responsibles of the inductive preoperative chemotherapy on the breast cancer were variable and we examined relations between age, chemotherapeutic regimens, size of tumor, mammographic and sonographic findings, hormonal factors in tumor mass and responsibles of the inductive chemotherapy in 44 cases of good responders among 101 casesofbreast cancer patient underwent preoperative inductive chemotherapy at Chungnam National University Hospital, from Jan. 1993 to Dec. 1997. The results of the study were obtained as follows: 1) The premanopause women were 29 patients (28.7%), postmanopause women were 15 patients (48.4%) and the response was good in postmanopause women than premanopause women (p"'0.06). 2) The good responders were underwent MMM regimen (46.3%) compare with FAC regimen (38.2%)(p=

0.07). 3) The result was good in smaller maximum diameter of initial tumor mass than larger one.

There were 86.7% of responders in less than 2cm of tumor size, 42.6% in 2-4em and 20.0% in more than 4 em (p=O.OOI). 4) The relations between degree of marginations, density, micro- calcification, spiculation on mammography and sonography and responsibles of inductive chemotherapy were no significant one, (Korean J of Breast Cancer 1998;1:257...262)

Key Words: The good responders, Inductive preoperative chemotherapy

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