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Protective effect of Nicotinamide on High glucose (HG)/Palmitate (PA)-induced Glucolipotoxicity to INS-1 beta cells

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Fig.  1.    Islet  β-cell  failure  and  the  natural  history  of  T2D.                    (Prentki  와  Nolan,  2006)
Fig.  2.  Effect  of  glucose  on  lipid  partitioning  in  the  beta  cell.  ( Poitout 등,  2010)  fatty  acid  (FA),  carnitine-palmitoyl  transferase-1  (CPT-1)
Fig.  3.  Supplement  of  TCA  cycle  intermediates  protects  against  high                      glucose/palmitate-induced  INS-1  beta  cell  death
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