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Solid and Papillary Epithelial Neoplasm of the Pancreas in Children

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= Abstract =

Solid and Papillary Epithelial Neoplasm of the Pancreas in Children

Seok Ho Choi, M.D., Dae Yeon Kim, M.D., Kwi Won Park, M.D.,

Sung Eun Jung, M.D., Seong Cheol Lee, M.D., Woo Ki Kim, M.D., Ja Jun Jang, M.D.*

Department of Surgery and Pathology*, Seoul National University Medical College Seoul, Korea

Six children with solid and papillary epithelial neoplasm of the pancreas were studied retrospectively. There were 2 boys and 4 girls. The mean age at opera- tion was 11 years(range; 8-13years). Three patients had incidental abdominal mass, in two patients the mass was non-tender, in one patient the mass was tender. The minimum size of tumor was 6.5 x 6.0 cm and the maximum was 10.5 x 8.0 cm. Five tumors were located in the head of the pancreas, and the other one in the tail. Local invasion or metastasis was not noticed. Tumors were re- moved completely by performing the following operations: 3 pylorous preserving pancreaticoduodenectomy, 2 Whipple's operation and 1 distal pancreatectomy.

There was no mortality. The histologic findings were characteristic. There were no recurrences during a follow-up of 0.5 to 12 years (mean; 5.0 years).

Index Words: Solid and papillary epithelial neoplasm, Pancreas, Children

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Of. 3).

Case Age/Sex Chief complaints LFT Serum amylase

1 13/F Nontender mass Normal Normal

2 12/M Tender mass Normal Normal

3 13/F Nontender mass Normal Normal

4 8/F Incidental mass Normal Normal

5 9/M Incidental mass Normal Normal

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Table 2. Operative Findings

Case Location Size(cm) Invasion

1 Head 9.5 x 9.0

2 Head 8.5 x 7.0

3 Head 7.5 x 7.0

4 Tail 10.5 x 8.0

5 Head 6.5 x 6.0

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Table 3. Postoperative Course

Case Complication

Metastasis Procedure

Whipple Whipple PPPD

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PPPD

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1. Cubilla AL, Fitzgerald PJ: Cancer(non- endocrine) of the pancreas. A suggested class if ication, in Fitzgerald P J, Morrison AB(eds): The Pancreas. Williams Wilkins, Baltimore, 1980, Pp 82-11

°

2. Morohoshi T, Held G, Kloppel G: Exo- crine pancreatic tumors and their histologi- cal classification: a study based on 167 autopsy and 97 surgical cases. Histopatho- logy 7: 645-61, 1983

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8. Todani T, Shimada K, Watanabe Y, Toki A, Fujii T, Urushihara N: Franz's tumor;

a papillary and cystic tumor of the pan- creas in girls. J Pediatr Surg 23: 116-121, 1988

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BR: Solid and papillary neoplasms of the pancreas. Yonsei Med J 37:131-141, 1996 11. ~'6"~, %.9.1~: ~~]?-J.9.1 %.!f--"J 'iPJ~ 2i!1] .5!.

.:iI . .±.0}9i:i!} 1: 79-84, 1995

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(6)

- i:°}91~ : ;1J] 4 i:! ;1J]1 ~ 1998\1 -

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x.AJ-&-,

{l~.£, ~~~, %~~: ~W7.J

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%!f-AJ '<fAJ%0J:.

tJ1~91~~~Al 38(2):

217-223, 1990

15. {l%-t},

7d

%{l , llH~7J: ~11AJ~

%!f-A J '<fAJ

~. tJ1~91~~~Al 43(2) :220-227, 1992 16. ;tj7cH-, :g-Jf.,

cl!f-{i,

~A~l%: ~lAJ~

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'<fAJ%0J:.

tJ1~91~~~Al 47(1):135-141, 1994

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cl78.!f-, 01%, cl:tPJ, 7J.::r-:

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'8-AJ~. tJ1~91~~~Al 48(5): 750-755, 1995

18. lif%Ell, cl~78,

Al-&-AJ,

{l~.£: ~lp(J~

%!f AJ '<fAJ"5'0J:.

tJ1~91~~~Al 50(7):1004- 1013, 1996

19. Choi BI, Kim KW, Han MC: Solid and papillary . epithelial neoplasms of the pan- creas: CT findings. Radiology 166:413- 416, 1988

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lary cystic carcinoma of the pancreas. J Surg Oncol 22:115-117,1983

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26. Miettinen M, Partanen S, Fr ki 0, Kivila- akso E: Papillary cystic tumor of the pan- creas, an analysis of cellular differen- tiation by electron microscopy and immu- nohistochemistry. Am J Surg Pathol 11:

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27. Kloppel G, Morohoshi T, John HD: Solid and cystic acinar cell tumor of the pancre- as : A tumor in young women with fa- vorable prognosis. Virchow Arch [PathoJ AnatJ 392:171-183, 1981

28. Rustin RB, Broughan T A, Hermann RE:

Papillary cystic epithelial neoplasms of the pancreas. Arch Surg 121: 1073-1076, 1986 29. Lack EE, Levey R, Cassady JR: Tumors

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Table  2.  Operative  Findings

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