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상시상정맥동내의 거대 거미막과립 1예

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Received: June 20, 2012 / Revised: July 17, 2012 / Accepted: August 7, 2012 Address for correspondence: Sung-Il Sohn, MD

Department of Neurology, Keimyung University School of Medicine, 56 Dalseong-ro, Jung-gu, Daegu 700-712, Korea Tel: +82-53-250-7075, Fax: +82-53-250-7840

E-mail: [email protected]

A 67-year-old woman presented with episodic headaches for 6 months. She had experienced these symptoms 4 times a month, typically beginning at the end of a day. The pain was described as similar to wearing a tight band around her head.

The headaches were bothersome, but not disabling, and she denied any nausea or vomiting. Neurological examinations were normal. Because she had a new-onset headache, brain magnetic resonance imaging (MRI) was performed to evaluate cerebral diseases. T2-weighted brain MRI showed heterogeneous hyperintense round mass within the superior sagittal sinus (Figure 1A). Axial T1-weighted enhanced MRI showed focal central enhancement in the sinus (Figure 1C). The non-contrast MR venogram revealed an oval shaped filling defect at the pos- terior third of the superior sagittal sinus (Figure 1D). The brain

parenchyma is of normal signal intensity with no focal lesions, mass effect or pathologic diffusion restriction. These findings suggested a giant arachnoid granulation in the superior sagittal sinus. Her symptoms seemed to be compatible with tension-type headache. The headache was successively managed with acet- aminophen 650 mg.

Arachnoid villi are microscopic growths of arachnoid mem- brane into the dural sinuses, whereas arachnoid granulations are visible to the naked eye and represent distended villi. We refer to arachnoid granulation as “giant” when it is of sufficient size to fill the lumen of a venous sinus and cause local dilatation of fill- ing defect.

1,2

Arachnoid granulations are never hyperdense on CT whereas venous sinus thrombosis has homogenous hyperden- sity on unenhanced CT. The typical findings of giant arachnoid NEUROIMAGING

Korean J Stroke 2012;14(2):92-93 http://dx.doi.org/10.5853/kjs.2012.14.2.92

상시상정맥동내의 거대 거미막과립 1예

대구파티마병원 신경과

1

, 계명대학교 의과대학 신경과학교실

2

박상원1·손성일2

A Case of Giant Arachnoid Granulation within Superior Sagittal Sinus

Sang-Won Park

1

and Sung-Il Sohn

2

1

Department of Neurology, Daegu Fatima Hospital;

2

Department of Neurology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea

FIGURE 1. (A) T2-weighted brain MRI showed an inhomogeneously hyperintense mass in the region of the superior sagittal sinus (arrow). (B) T1-weighted MRI showed an hypointense mass. (C) Axial T1-weighted enhanced MRI showed focal enhancement centrally. (D) The MR venogram revealed an oval shape filling defect within the posterior third of the superior sagittal sinus (arrowhead).

A B C D

92 ISSN 1229-4101 Copyright ⓒ 2012 Korean Stroke Society

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Sang-Won Park, et al.

www.stroke.or.kr 93 granulations are focal non-enhancing granules with central

focal enhancement and surrounding enhancing flowing blood on MR venography.

3

Arachnoid granulations within venous sinus sometimes make imaging interpretation difficult, particularly in patients with headache complaints in whom venous sinus throm- bosis is a matter of concern. Although largely incidental, giant arachnoid granulations can rarely cause symptoms and surgical intervention is not thought to be necessary.

Conflicts of Interest

The authors have no financial conflicts of interest.

REFERENcEs

1. Mamourian AC, Towfighi J. MR of giant arachnoid granulation:

a normal variant presenting as a mass within the dural venous sinus. Am J Neuroradiol 1995;16:901-904.

2. Sunbulli M, Zak I, Chaturvedi S. Giant arachnoid granulations.

Neurology 2005;64:2150.

3. Dormont D, Sag K, Biondi A, Wechsler B, Marsault C. Gado-

linium-enhanced MR of chronic dural sinus thrombosis. Am J

Neuroradiol 1995;16:1347-1352.

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