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Laparoscopic pancreaticoduodenectomy for periampullary tumors: A contraindication for octogenarians?

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AHBPS

Annals of Hepato-Biliary-Pancreatic Surgery

www.ahbps.org S359

Laparoscopic pancreaticoduodenectomy for periampullary tumors:

A contraindication for octogenarians?

Ji Su KIM

1,2

, Munseok CHOI

1,2

, Sung Hyeon KIM

1,2

, Sung Hoon CHOI

3

, Chang Moo KANG*

,1,2

1

Department of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine, Seoul, Korea

2

Department of Pancreatobiliary cancer center, Yonsei Cancer Center, Severance Hospital, Seoul, Korea

3

Department of Hepatobiliary and Pancreatic Surgery, CHA Bundang Medical Center, Seongnam, Korea

EP-160

Introduction: With continued technical advances in surgical instruments and the growing surgical expertise, many laparoscopic pancreaticoduodenectomies (LPDs) have been safely performed with favorable outcomes, and this approach is being used more fre- quently. Interest in treatments for elderly patients has increased with life expectancy. We investigated safety and feasibility of LPD in ontogenarians.

Methods: From September 2005 to February 2020, resectable/borderline resectable periampullary tumors (PATs) were diagnosed in 71 octogenarians at Sincheon Severance Hospital and CHA Bundang Medical Center. Patients were divided into two groups: those who underwent surgery (N = 38) and those who did not (N = 33). The surgery group was further divided into two groups: those who underwent open pancreaticoduodenectomies (PDs) (OPDs) (N = 19), and those who underwent LPDs (N = 19). Perioperative out- comes, including long-term survival, were retrospectively compared.

Results: There was no significant difference in age, sex, comorbidities, diagnosis, and chemo-radiotherapy between the surgery and non-surgery groups. The surgery group had a better survival rate than the non-surgery group ( p < 0.05). Baseline characteristics and postoperative outcomes were not significantly different between the OPD and LPD groups. Only three patients in the OPD group and two patients in the LPD group had a biochemical leak ( p > 0.05). There was no significant difference between the OPD and LPD groups in overall survival and disease-free survival ( p = 0.816, p = 0.446, respectively).

Conclusions: PD can improve survival outcome in octogenarian patients with PATs. Even LPD can be carefully performed with com- parable oncologic outcomes in well-selected octogenarian patients.

pISSN: 2508-5778ㆍeISSN: 2508-5859

Ann Hepatobiliary Pancreat Surg 2021;25 Suppl 1:S359 https://doi.org/10.14701/ahbps.EP-160

Corresponding Author: Chang Moo KANG ([email protected]) Presenter: Ji Su KIM ([email protected])

Copyright Ⓒ The Korean Association of Hepato-Biliary-Pancreatic Surgery

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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1 Department of Internal Medicine, Bundang Jesaeng General Hospital, Seongnam, Korea, 2 Department of Laboratory Medicine, Bundang Jesaeng General Hospital, Seongnam, Korea,

Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang- gu, Seongnam 13620, Korea..

2 Division of Colorectal Surgery, Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea. 3 Division of Colorectal Surgery, Department of Surgery,

1 Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.. 2 Division of Transplantation Surgery, Department

Young-Kyun Lee, Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 463-707, Korea.. Tel:

c Department of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.. d

Department of Psychiatry 6 , Kangbuk Samsung Hospital, College of Medicine, Sungkyunkwan University School of Korea, Seoul,.. Department of Psychiatry 7 , CHA Bundang Medical

2 Department of Pediatrics, Korea Cancer Center Hospital, Seoul; 3 Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam; 4 Department of Pediatrics,