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Multi-center comparative study between totally laparoscopic and robotic pancreaticoduodenectomy: Propensity score and learning curve matching analysis

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AHBPS

Annals of Hepato-Biliary-Pancreatic Surgery

www.ahbps.org S81

Multi-center comparative study between totally laparoscopic and robotic pancreaticoduodenectomy:

Propensity score and learning curve matching analysis

Hyeyeon KIM

1

, Jae Hoon LEE*

,1

, Chang Moo KANG

2

, Sung Hoon CHOI

3

1

Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, Asan Medical Center, Seoul, Korea

2

Division of HBP surgery, Department of Surgery, Yonsei University College of Medicine, Pancreatobiliary Cancer Center, Severance Hospital, Seoul, Korea

3

Division of Hepatobiliary and Pancreas, Department of Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea

BP-OP-2-1

Introduction: Minimally invasive surgery has been adopted in pancreaticoduodenectomy (PD) recently, though there have been few reports comparing totally robotic PD (TRPD) to totally laparoscopic PD (TLPD).

Methods: Retrospective multi-center analysis was performed regarding TLPD and TRPD from the initial case of each three surgeons to June 2020. Perioperative outcomes were analyzed using propensity score matching (PSM). Additional PSM analysis was done after excluding cases before reaching learning curve maturity to minimize technical biases.

Results: A total of 362 cases were included (TLPD 282 and TRPD 80). Mean age was 61.7 ± 11.9 years, younger in TRPD (56.4 ± 9.9 vs. 63.2 ± 12.1, p < 0.001). Malignancy rate reported 72.5% in TRPD, and 85.5% in TLPD (p = 0.011). There was one case of mortality.

Operative time was shorter in TRPD (409.1 ± 77.4 vs. 455.3 ± 75.1 min, p < 0.001). Postoperative hospital stay was also shorter in TRPD (11.7 ± 6.3 vs. 17.1 ± 11.7 days, p < 0.001). Conversion rate was 10.3% in TLPD, while no conversion in TRPD (p < 0.001). There were no significant differences in major complications (Clavien-Dindo ≥ III) or clinically-relevant postoperative pancreatic fistula (CR-POPF).

R0 resection rate was 94.9% in TRPD, and 92.8% in TLPD. The number of retrieved lymph nodes showed higher in TRPD (17.1 ± 7.9 vs. 12.6 ± 8.7, p < 0.001). After PSM, operative time (411.6 ± 75.4 vs. 452.6 ± 76.8, p = 0.001) and hospital stay (11.9 ± 6.5 vs. 14.6 ± 7.8, p = 0.027) reported shorter in TRPD. Major complications and CR-POPF showed no significant differences. Likewise, after excluding immature cases, additional PSM analysis showed similar results for operative time, hospital stay and complications including CR- POPF.

Conclusions: Both TRPD and TLPD are safe and feasible approaches showing comparative complications. TRPD showed shorter op- erative time and hospital stay, though there were no differences in major complications or CR-POPF.

pISSN: 2508-5778ㆍeISSN: 2508-5859

Ann Hepatobiliary Pancreat Surg 2021;25 Suppl 1:S81 https://doi.org/10.14701/ahbps.BP-OP-2-1

Corresponding Author: Jae Hoon LEE ([email protected]) Presenter: Jae Hoon LEE ([email protected])

Copyright Ⓒ The Korean Association of Hepato-Biliary-Pancreatic Surgery

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Department of Orthopaedic Surgery, Yongdong Severance Hospital, Yonsei University College of Medicine, Department of Orthopaedic Surgery, Anam Hospital, Korea

Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea Behcet's disease (BD) is a multisystem inflammatory

2 Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul,

2 Department of Laboratory Medicine, Severance Hospital, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.. Received: April 3,

1 Department of Nuclear Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, 2 Molecular Imaging Research Center, Korea Institute of

1 Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul; 2 Department of Pediatric Surgery,

1 Department of Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, 2 Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery,

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