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A Case with Splenic Tuberculosis

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= Abstract =

A Case with Splenic Tuberculosis

Doo-Sun Lee, M.D., Na Hye Myong, M.D.

Section of Pediatric Surgery, Departments of General Surgery and Anatomic Pathology, College of Medicine, Dankook University, Cheonan, Korea

Splenic tuberculosis is an uncommonly considered diagnosis in clinical practice.

This is a case report of splenic tuberculosis in a 13-year-old boy who was seronegative to HIV. He was just well until 7 days prior to this admission when he started to feel epigastric and left subchondral pain. Chest

X

-ray was not pathological. Abdominal ultrasonography showed slight splenomegaly with multi- ple hypoec:hoi<: nod\\\e-s a\\d abdl)ID.lna\ (,1' uisdosea mu)tip)e irregular hypodense lesions in the spleen. Radiological interpretation suggested the possibility of lym- phoma or metastatic malignancy. Splenectomy was done and the histopathologic- al findings showed extensive chronic: granulomatous inflammation compatible with tuberculosis. Splenic tuberculosis 1l1ust be included in the differential diag- nosis of hypoechoic and hypodense lesions by means of sonography and comput- ed tomography, respectively.

Index Words: Spleen, Tuberculosis.

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Fig. 1. Sonogram shows multiple hypoechoic lesions all over the spleen with slight irregular margins.

Fig. 2. An abdominal CT scan shows multiple hypodense nodules in an enlarged spleen.

Fig. 3. Cut-surface of the spleen shows various sized nodular masses with irregular margins in the entire crgan.

Fig. 4. Exuberant tuberculoid grannulomas destroy almost entire parenchyma, with central caseation necrosis and Langhans-type giant cells (HE, x 100).

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REFERENCES

1. Kang GH, Chi JG : Congenital tuberculosis.

J Kor Med Sci 5 : 59-64, 1990

2. Chapman AZ, Reeder PS, B&ker LA : Neu- tropenia secondary to tuberculous spleno- megaly : Report of a case. Ann Intern Med

41 : 1225-1231, 1954

3. Rao RCk, Ghose R, Sawhney S, Berry M : Hemangioma of spleen with tuberculosis, extra-peritoneal rupture, with associated splenic tuberculosis-an unsual presentation.

Australas Radiol 37 : 100-101, 1993

4. Weiner JJ, Carter RF : Acute thrombocyto- penic purpura(hemorrhagic) associated with tuberculosis (miliary) of the spleen. Ann Surg 113: 57-61, 1941, cited from Chap- man AZ, Peeder PS, Baker LA : Neutrope- nia secondary to tuberculous splenomega- ly : Report of a case. Ann Intern Med 41 :

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1225-1231, 1954

5. Machiels G, De Baetselier H: An unusual echographic appearance of the spleen in tu- berculosis. Trop Doct 22 : 190-191, 1992 6. Pedro-Botet J, Maristany MT, Miralles R,

Lopez-Colomes JL, Rubies-Prat J : Splenic tuberculosis in patients with AIDS. Rev In-

fect Dis 13 : 1069-71, 1991

7. Denton T, Hossain J : A radiological study of abdominal tuberculosis in a Saudi popu- lation, with special reqerence to ultrasound and computed tomography. Clin Radiol 47 : 409-414, 1993

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수치

Fig.  1.  Sonogram  shows  multiple  hypoechoic  lesions  all  over  the  spleen  with  slight  irregular  margins

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