• 검색 결과가 없습니다.

목적: ࠉ१ৡҿछ੹ ѿ଒‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ ൝ઘઅ ઑࣛ৩ࣛӘ ࢅҁࣽ‫ز‬௖஬ਕ੹ ઊੋടਉ ௐીഡ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖ ࠃ ൠࠉࡘ ३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ࡻ ݴ‬ӯന ࡂӋઘ ടਔ‫د‬

N/A
N/A
Protected

Academic year: 2021

Share "목적: ࠉ१ৡҿछ੹ ѿ଒‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ ൝ઘઅ ઑࣛ৩ࣛӘ ࢅҁࣽ‫ز‬௖஬ਕ੹ ઊੋടਉ ௐીഡ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖ ࠃ ൠࠉࡘ ३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ࡻ ݴ‬ӯന ࡂӋઘ ടਔ‫د‬"

Copied!
8
0
0

로드 중.... (전체 텍스트 보기)

전체 글

(1)Journal of the Korean Glaucoma Society 2016;5(2):46-53. Original Article. ࠉ१ৡҿछ੹ࡂઊ‫ޔٳࡻؘ‬ਐऀৗളേ१३ӄ࠾଑Әીࣛ৊৒‫ֳפ‬ણઅ ࡻӯ Comparison between Nonarteritic Anterior Ischemic Optic Neuropathy and Normal Tension Glaucoma with Altitudinal Visual Field Defect 강연수, 성미선, 박상우 Yeon Soo Kang, MD, Mi Sun Sung MD, Sang Woo Park, MD ᱥԉ‫⦺ݡ‬Ʊ᮹ŝ‫ᦩ⦺ݡ‬ŝ⦺Ʊᝅ Department of Ophthalmology, Chonnan National University Medical School, Gwangju, Korea. 목적: ࠉ१ৡҿछ੹ ѿ଒‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ ൝ઘઅ ઑࣛ৩ࣛӘ ࢅҁࣽ‫ز‬௖஬ਕ੹ ઊੋടਉ ௐીഡ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖ ࠃ ൠࠉࡘ ३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ࡻ ݴ‬ӯന ࡂӋઘ ടਔ‫د‬. 대상과 방법: ࣛௐ ۙ‫ ؘ‬ടௐ ࠉ१ৡҿछ੹ ѿ଒޷ࣳ ࠋ࠾ 6ґਖ਼ ઊ൲ १३ӄ੭‫ࡘڂ‬૚ઊ ৺‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑ 24޻ 24৊Ә १ৡҿछઅ ી٩ ࠃ ֢ઊѿ ࡻ॥ഡ ીࣛ৊৒‫ֳפ‬ણ ൝ઘ 26޻ 26৊੹ ‫ ܾ੶ࣛف‬Ԟࡅહઌ ಡऀ ࠃ ࢅҁࣽ‫ز‬௖஬ਕઅ ௐી҈੹ ࡻӯടਔ‫د‬. ۙഡ १ৡҿछઅ ੥ௗѿ Ҏ੸ ൝ઘ‫ݩ࡚ ੹ڝ‬ടਉ ҀҀ ࢅҁࣽ‫ز‬௖஬ਕ ௐી҈੹ ࡻӯടਔ‫د‬. 결과: ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑ ൝ઘ‫ࡻ ਁڝ‬ന ીࣛ৊৒‫ֳפ‬ણ ൝ઘઅ १ܲઊ ੭અടҲ ૝৔Ӌ(p =0.035), ࣛௐ १ৡҿछ੹ ѿ଒‫ؘ‬ ൝ઘ‫ڝ‬અ ࡻੰઊ ੭અടҲ ‫׬‬৔‫(د‬p =0.001). ࢅҁࣽ‫ز‬௖஬ਕҿӘ ીࣛ৊৒‫ֳפ‬ણ ൝ઘ‫ڝ‬અ १३ӄࣼ੭౫અ ޷હઊ ੭અടҲ હৼ੶޵ (p <0.001), ೤ԑ १३ӄ੭‫ڂ‬ത߂ࡻ‫ ؘ‬੭અടҲ ௽‫(د‬p <0.001). ೤ԑ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖ ࠃ ೤ԑ ൠࠉࡘ ३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ ڂ ؘ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ৺ৼ੶֢, ઊௐ ‫ޅޏ‬३ӄࣼ੭௖ ‫ڂ‬Ռਁ ੭અഡ ୱઊѿ ઔৼӋ(p =0.017), १ৡҿछઅ ੥ௗѿ Ҏ੸ ‫ݼ֚؁‬ ࡻӯടਔ੹ ӄੌ ࣛௐ ࠃ ടௐ १ৡҿछ ޾‫ࡻ ڂ‬ௐ ൠࠉࡘ ३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռਁ ੭અഡ ୱઊѿ ઔৼ‫ࣛ(د‬ௐ १ৡҿछ, p =0.049; ടௐ १ৡҿछ, p =0.034) 결론: ࠉ१ৡҿछ੹ ѿ଒‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ ൝ઘਁࣳ ઊௐ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռਁ ੭અഡ ୱઊѿ ઔৼ‫د‬. ۙഡ १ৡҿछઊ Ҏ੸ ੥ௗਁ ઔ‫ ؘ‬൝ઘ‫ࡻ ݼ֚ڝ‬ӯയ੹ ‫ࣛ ڹ‬ௐ, ടௐ १ৡҿछ ޾‫ࡻ ڂ‬ௐ ൠࠉࡘ ३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռਁ ੭અഡ ୱઊѿ ઔ੻੹ ্ ़ ઔৼ‫د‬. Key words: Altitudinal visual field defect, Non-arteritic anterior ischemic optic neuropathy, Normal tension glaucoma, Optical coherence tomography. 서 론. સട‫ ؘ֢ౌ֢ ݴ‬ҫઊ ಡଛહઊӋ, ‫ऀކ‬Ԟܾ ଔരട޷ १३ӄࣼ ੭౫‫فࣛ ؘ‬હ੶ܾ ੭଒‫ ֢ٻ‬१३ӄ੭‫ࠕ୺ ڂ‬ઊ ֢ౌ֥‫د‬.2,3 ࠉ. ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ੸ १३ӄਁ 1. ޷ ીࣛ৊৒‫ֳפ‬ણ੸ ஢Ԟਁ १३ӄઅ ࣛௐ ࠃ ടௐઅ ஸ࣐ઊ. ࡻѿਊહઌ छࣛ੹ ૵ ़ ઔ‫ ؘ‬ଖ൝‫ڝ‬ઊ‫د‬. ࡻ‫ޔٳ‬ਐऀ ৗളേ१. छࣛ੹ ࠊৈ ‫ޅޏ‬३ӄं೩અ छ५ઊ ࠋࣥടӋ, १३ӄ੭‫ڂ‬ത߂. ३ӄ࠾଑੸ १३ӄઅ ࡘ૚Ә തՌ ౿଑ઊ ৺‫҇ ؘ‬ઙफ़‫ܟ‬੎ १ܲ. ࡻѿ ଑ѿടਉ १३ӄࣼ੭౫ѿ ৥ৈ଒Ҳ ‫دټ‬.3,4 ઊ‫ܨ‬Ҳ ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણઅ १. Received: 2016. 9. 5. Accepted: 2016. 11. 15.. Revised: 2016. 11. 4.. Corresponding Author: Sang Woo Park, MD, PhD Department of Ophthalmology, Chonnam National University Hospital, #42 Jebong-ro, Dong-gu, Gwangju 61469, Korea Tel: 82-62-220-6742, Fax: 82-62-227-1642 E-mail: [email protected]. ३ӄ੭‫ڂ‬અ ޾৩ઊ ‫܅ًݱد‬٩ ‫ ڂ‬ଖ൝ਁ અഡ १ৡҿछ੸ ࡻ॥ ഡ ৩ࣛ੶ܾ ֢ౌ֧ ़ ઔ‫ؘ‬ٙ, ‫ૻޅޏ‬७ࡘਁࣳઅ ‫ޅޏ‬१३ӄࣼ ੭ ஸ࣐અ ࡚೩ ୱઊ ‫ࣛ ਁߚڹ‬ௐӘ ടௐ ࠉ१ৡ ࣏ઊਁ ࡻ‫ف‬௠ હ੶ܾ ֢ౌ֧ ़ ઔ‫د‬.5 ઊ‫ࠉ ܡ‬१ৡҿछઊ ઔ‫ ؘ‬൝ઘ‫ ࣳਁڝ‬ಡ ଛહઌ ଑ࣛઊ֢ ಡ࠺ഡ Әңܲઊ ৺‫ޔٳࡻ ޷د‬ਐऀ ৗളേ१३ ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ੹ ҆࠺ടԞ ৰܱ੏ ़ ઔ‫د‬.6. Journal of the Korean Glaucoma Society.

(2) ҋ਌़਼ളേ१३ӄ࠾଑Ә‫ֳפ‬ણઅࢅҁࣽ‫ز‬௖஬ਕघҽࡻӯ. A. B. 47. ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռѿ ҆घട޷ࣳ ൠࠉࡘ ३ӄ઻ं ೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬ՌԪ଒ ҆घഡ‫ ؘد‬ҫ੸ ‫ ੸އ‬਌Ӵਁࣳ ࠌൄଔ ࠅ ઔ‫د‬.7–20 ԓ‫ݼ‬Ӌ மԕਁ‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ‫פ‬ ֳણ ൝ઘਁࣳ ࢅҁࣽ‫ز‬௖஬ਕ੹ ઊੋന १३ӄ੭‫ڂ‬અ Ӵ૒હ ࠹൛‫ࡻ ݴ‬ӯഡ ਉ‫ ܟ‬਌Ӵѿ ࠋ೵‫دৼٻ‬.1,4,6,21,22 ട଒‫ ކ‬Fard et al4 અ ਌Ӵ‫਼ૂ ݴ‬ടӋ‫ ؘ‬੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖Ә ൠࠉࡘ ३ӄ ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ ݴ‬Ҏઊ ࡻӯട଒ ৌ৔Ӌ, १ৡҿछઅ ৩ ࣛઊ֢ ੥ௗ‫ ݴ‬Ӌܱട଒ ৌ৔‫ૂ ؘد‬ഡઽઊ ઔ‫د‬.. C. D. ‫ ࡅ ࣳ܅گ‬਌Ӵਁࣳ‫ࠉ ؘ‬१ৡҿछ੹ ѿ଒‫ޔٳࡻ ؘ‬ਐऀ ৗളേ १३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ ൝ઘઅ ઑࣛ৩ࣛӘ ࢅҁࣽ‫ز‬௖஬ ਕ੹ ઊੋടਉ ௐીഡ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖ ࠃ ൠࠉࡘ ३ӄ ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ࡻ ݴ‬ӯന ࡂӋઘ ടਔ‫(د‬Fig. 1).. 대상과 방법 2012‫ ך‬1ਖ਼ࡘౡ 2015‫ ך‬12ਖ਼Ԫ଒ ࡅ੘ਁ ֳ੘ഡ ࠉ१ৡҿछ੹ ѿ଒‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑ ൝ઘ 24޻ 24৊, ીࣛ৊৒. E. F. ‫ֳפ‬ણ ൝ઘ 26޻ 26৊੹ ‫ ܾ੶ࣛف‬અߗԞܿ੹ ൲ലહ੶ܾ ࡚ࣴ ടਔ‫د‬. ޾‫ ڛ‬൝ઘ‫ܲ࠾ ܾ੶ࣛف ੹ڝ‬૒࣏, ம‫ف‬ӯી१ܲௐી, ӏ ‫ކڙ‬৒೤৊৒ӆ‫ ݴ‬ઊੋഡ ৊৒ௐી, ৊સҩ࣏, ‫ޅޏ‬३ӄࣼ੭௖ ࠃ १३ӄ੭‫࣏ڂ‬ଔ஬ਕ, ࢅҁࣽ‫ز‬௖஬ਕ, १ৡҩ࣏‫ ݴ‬१രടਔ ‫د‬. ࠕֳણ़ी ઊ਼અ ৊Ә ़ीઅ Әңܲઊ ઔң֢ १ৡҩ࣏ਁ ਕല੹ ߸௛ ़ ઔ‫ ݳد ؘ‬৊Әહ ଖ൝ઊ ઔ‫ ؘ‬ӄੌ, Ӵ޷‫੾ف‬ௗ ѿ -6D ઊടઅ Ӌ٩ԕ१‫਼ૂ ࣳਁࣛف ؘ‬ടਔ‫د‬. ۙഡ ࡅ ਌Ӵ‫ؘ‬. G. H. ࡅ੘અ ࣥ޻અഠ਌Ӵ੯‫ݼ‬७અ੥੘൦અ ०ઌ੹ ౿Әടਉ ଔര‫ٻ‬ ৼ‫د‬. ࠉ१ৡҿछ੸ സ഑‫ݼ‬ઘ‫ٳ‬१ৡӆ(% „Š

(3) 

(4) „–અ    

(5)  ‡  

(6)  અ central 30-2 ҩ࣏ਁ ࣳ ࣛௐ ൒੸ ടௐ ࠉ१ৡਁࣳ ‫ ं ੻د‬ѿ଒ Ԟ૴ ૻ ‫ ڂ‬ѿ଒ ઊ ࣛ੹ ‫ކ‬૓ട‫ ؘ‬ӄੌ([1] Pattern deviation plotઅ ѿણઘ‫ૂ ݴݼ‬ ਼ഡ ࡘ੥ਁࣳ ઌાഡ 3ґ ઊࣛ ઽઅ ਊௗѿ ીࣛઅ 5% ߸‫ܾ੶ކ‬. Figure 1. Fundus photography (A, B), the result of visual field. ֢ౌ֢Ӌ ԓૻ ഡ ґ ઊࣛ੸ 1% ߸‫ކ‬ઊң֢, [2] Pattern standard. test (C, D), peripapillary retinal nerve fiber layer thickness (E, F), and macular ganglion cell-inner plexiform layer thickness (G, H). Non-arteritic anterior ischemic optic neuropathy (A, C, E, G) and normal tension glaucoma (B, D, F, H). S = superior; N = nasal; I = inferior; T = temporal.. deviation (PSD)ઊ 5% ߸‫ކ‬ઊң֢¯™±Z

(7) 

(8)  Š   (GHT)ਁࣳ outside normal limits), ԓ‫ݼ‬Ӌ ࠉ‫ف‬ௐ ࠉ१ৡਁࣳ pattern deviation plotਁࣳ ं ґ ઊࣛઅ ਌ङ‫ ټ‬଒ઽਁࣳ ਊௗѿ 5% ߸‫ކ‬ઌ ઽઊ ૔થട଒ ৌ੶޷ࣳ ‫ ڂ‬ґ ઊࣛઅ ਌ङ‫ ټ‬଒ઽਁࣳ ਊௗѿ 1% ߸‫ކ‬ઌ ઽઊ ૔થട଒ ৌ‫ ؘ‬ӄੌܾ ીઅടਔ‫د‬. ૲१ࣛ. ࢅҁࣽ‫ز‬௖஬ਕઊ ٩઒‫ޔٳࡻ ࣳ޷ٻ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણਁࣳ १३ӄ੭‫ڂ‬અ ࠹൛‫ ݴ‬Ӵਊ࠺ܾ ֢‫׿‬ৰ Ӵ. ५ 20% ઊࣛ ۙ‫ ؘ‬੥৩ऀ‫ݬ‬Ә ੥੻ऀ‫ ݬ‬15% ઊࣛઅ ३݊٩ѿ ‫ۅ‬ ৰ଒‫ ؘ‬ӄੌ‫਼ૂ ࣳਁࣛف ؘ‬ടਔ‫د‬.23. ૒હઌ ࡚ࣴઊ ѿ‫؟‬ടҲ ‫دৼٻ‬. ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ә. ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑੸ ౿଑ઊ ৺‫҇ ؘ‬ઙफ़‫ܟ‬੎ १ܲ. ીࣛ৊৒‫ֳפ‬ણ ‫ ڂ‬ଖ൝ ޾‫ࢅ ࣳਁڂ‬ҁࣽ‫ز‬௖஬ਕ੶ܾ ௐીഡ. સടਭ തՌ १३ӄ੭‫ڂ‬અ ࡘ૚ ۙ‫ ؘ‬஺േ੹ ࡂઊӋ १३ӄ੭‫ڂ‬. www.koreanglaucoma.org.

(9) 48. JOURNAL OF THE KOREAN GLAUCOMA SOCIETY. 9ROXPH_1XPEHU. અ ઊࣛघҽӘ ਌Ӛ‫ࠉ ټ‬१ৡҿछઊ ઔ੶޵ ҇ઙफ़‫ܟ‬੎ १ܲસട. ֳણ ‫ ڂ‬Ӷ ҁઅ ࢅҁࣽ‫ز‬௖஬ਕ ௐીௗ‫ࡻ ݴ‬ӯടਔӋ, ࠉ१ৡҿ. ֢ १ৡҿछઅ ੘ઌઊ ‫ކ ٽ‬ഡ ‫ ݳد‬৊Әહઌ ଖ൝ઊ ৺‫ ؘ‬ӄੌܾ. छઅ ੥ௗѿ ࣛௐઌ ൝ઘ‫ڝ‬Ә ടௐઌ ൝ઘ‫ ੹ڝ‬ҀҀ ֢‫׿‬ৰ ‫ڂ‬. 24. ીઅടਔ‫د‬. ࠋ࠾ 6ґਖ਼ઊ ଒֢଒ ৌң֢ १३ӄ੭‫ࡘڂ‬૚ઊ ֪. Ӷ ҁઅ ࢅҁࣽ‫ز‬௖஬ਕ ௐીௗ‫ࡻ ݴ‬ӯടਔ‫د‬. ३൑ҋ٩ѿ 5 ઊ. ৈઔ‫ ؘ‬ӄੌ, ৊Ӵ੎‫ ٳ‬१ ౿଑੹ ‫ࠉٳ‬ഡ ӄੌ, ‫ޔٳ‬ਐऀ ৗളേ. ടઌ ӄੌਁ‫਼ૂ ࣳਁࣛف ؘ‬ടਔ‫د‬.. १३ӄ࠾଑੹ १࣏ഢ ़ ઔ‫ ؘ‬२੅સട, मৢ҆, ౢ ಶര ‫ڢ‬ઊ ઔ. ౿ӆഠહ ࡚ࣴ੸—'^  !ˆ'• 

(10) . ‫ ؘ‬ӄੌ, १३ӄ੹ ৒ࠆടӋ ઔ‫࠹࠾ ؘ‬ઊ ઔ‫ ؘ‬ӄੌ‫਼ૂ ؘ‬ടਔ. IL, USA)‫ ݴ‬ઊੋടਔ‫د‬. Ҁ Ӷ ҁઅ ֢ઊ, १ܲ, ৊৒, १ৡҩ࣏. 22. ‫د‬. ીࣛ৊৒‫ֳפ‬ણ੸ ‫ֳפ‬ણऀ १३ӄछࣛઊ ઔӋ ઊਁ ഥ‫ؽ‬. ࠃ ࢅҁࣽ‫ز‬௖஬ਕઅ ௐીௗ‫ࡻ ݴ‬ӯടԞ ੥ന Mann-Whitney. ഡ ࠉ१ৡҿछઊ ઔ੶޷ࣳ ৊৒ઊ 21 mmHg ઊടઊӋ ઺ࠒҀ੸. U -test‫ ݴ‬१രടਔӋ, Ҁ Ӷ ҁઅ ऀ࠺, ೟ௐऀ, १ৡҿछઅ ੥ௗ. ਍‫ ౖܾࣛ ݾ‬ીઅടਔ‫د‬. ৊৒ઊ 22 mmHg ઊࣛઊң֢ ૲࠹൙୼. ‫ࡻ ݴ‬ӯടԞ ੥ന Chi-square test‫ ݴ‬१രടਔ‫د‬. p҈ઊ 0.05 ߸‫ކ‬. ৗ੭୲ઊ ઔ‫ ؘ‬ӄੌ, ‫ֳפ‬ણ ‫ܩ‬ઊસௗ‫ ੸ࠊ ݴݑ‬ӄੌ‫ࣳਁࣛف ؘ‬. ઍ ӄੌ‫ ݴ‬౿ӆહ੶ܾ ੭અഡ ҫ੶ܾ ીઅടਔ‫د‬.. ૂ਼ടਔ‫د‬. ࢅҁࣽ‫ز‬௖஬ਕ੸ Cirrus HD-OCT (Carl Zeiss Meditec,. 결과. Dublin, CA, USA)અ Optic disc cube 200 ⅹ 200 scan mode‫ݴ‬ ઊੋടਉ १३ӄ੭‫ૻ ݴڂ‬७੶ܾ ѿܾ ंܾ 6 mm ࣏Ҁൌ ࡘ੥. ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑ӶӘ ીࣛ৊৒‫ֳפ‬ણӶઅ ೤. ‫ ݴ‬200ґܾ ԑ‫ڢ‬ඥ ࡚ഢ ൲ ‫ ؽ޷ز‬200ґઅ A-scan੹ ౿ന ৴ৰ. ԑ ֢ઊ‫ ؘ‬62.79 š 9.72ं, 60.50 š 11.95ंਔӋ, ࡻ‫ޔٳ‬ਐऀ ৗ. ଔ ઘ‫ ࣳਁݑ‬१३ӄ੭‫ૻ ڂ‬७੶ܾࡘౡ 3.46 mm ଒‫ݵ‬અ ੘ਁࣳ. ളേ१३ӄ࠾଑Ӷઅ ֪ઘ‫ ؘ‬18޻, ਉઘ‫ ؘ‬6޻, ીࣛ৊৒‫ֳפ‬ણ. ௐીௗ‫ ݴ‬ஷ஺ടਉ १३ӄ੭‫ڂ‬અ ޷હӘ १३ӄ੭‫ڂ‬ത߂ࡻ, १. Ӷઅ ֪ઘ‫ ؘ‬11޻, ਉઘ‫ ؘ‬15޻੶ܾ ‫ ڂ‬Ӷਁࣳ ೤ԑ਌ܹӘ ऀ࠺. ३ӄ੭‫ڂ‬౫અ ޷હ੹ ӴടਔӋ, ೤ԑ ࠃ ࣛௐ, ടௐ, ઊௐ, ࡻௐ,. અ ੭અഡ ୱઊ‫ ؘ‬৺ৼ‫د‬. ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑ӶӘ ી. ԓ‫ݼ‬Ӌ १ӆ࡚઻ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռ‫ ݴ‬ௐીടਔ. ࣛ৊৒‫ֳפ‬ણӶઅ ம‫ف‬ӯી१ܲ(LogMAR)੸ ҀҀ 0.27 š 0.37,. 25. ‫د‬. ൠࠉࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖੸ Macular cube 512 ⅹ. 0.08 š 0.13੶ܾ ࡻ‫ޔٳ‬ਐऀ ৗളശ१३ӄӶਁࣳ ம‫ف‬ӯી१ܲ. 128 scan੹ ઊੋടਉ ൠࠉࡘ੥અ 6 ⅹ 6 ⅹ 2 mm ੮޷ஔਁࣳ ഡ. ઊ ੭અടҲ ֢ࢎӋ(p =0.035), ೤ԑ ৊৒੸ ҀҀ 14.63 š 1.84. ޷‫ ؽ‬128ґઅ A-scanӘ 512ґઅ B-scan੹ ౿ന ൠࠉࡘ‫ૻ ݴ‬७. mmHg, 13.96 š 2.22 mmHgܾ ౿ӆહ੶ܾ ੭અഡ ୱઊ‫ ؘ‬৺ৼ. ੶ܾ ѿܾ 1.2 mm, ंܾ 1.0 mmઅ ౌ੘ൌ Ӌ‫਼ૂ ݴݼ‬ഡ ѿܾ. ‫د‬. ࡻ‫ޔٳ‬ਐऀ ৗളശ१३ӄӶਁࣳ ੌ৊੸ 16৊, ૞৊੸ 8৊ઊ. 4.8 mm, ंܾ 4.0 mmઅ ౌ੘ൌ Ӌ‫ ࣳਁݼ‬ௐીௗ‫ ݴ‬ஷ஺ന ೤ԑ. ৼӋ ીࣛ৊৒‫ֳפ‬ણӶਁࣳ ੌ৊੸ 13৊, ૞৊੸ 13৊੶ܾ ೟ௐ. ࠃ ࡘ୼՝ Ӵਊ࠺(ࣛࡻௐ, ࣛௐ, ࣛઊௐ, ടઊௐ, ടௐ, ടࡻௐ) ‫ڂ‬. ऀਁ ੭અഡ ୱઊ‫ ؘ‬৺ৼӋ, ࡻ‫ޔٳ‬ਐऀ ৗളശ१३ӄӶਁࣳ ࣛ. 26. Ռ‫ ݴ‬ௐીടਔ‫د‬. ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫פ‬. ௐ ࠉ१ৡҿछ੸ 6৊, ടௐ ࠉ१ৡҿछ੸ 18৊ઊৼӋ ીࣛ৊৒. Table 1. Baseline characteristics of patients. NAION (n = 24). NTG (n = 26). p -value. Age (years). 62.79 ± 9.72. 60.50 ± 11.95. 0.515*. Sex (M/F). 17/7. 11/15. 0.040†. 0.27 ± 0.37. 0.08 ± 0.13. 0.035*. 14.63 ± 1.84. 13.96 ± 2.22. 0.202*. OD/OS. 16/8. 13/13. 0.183†. Upper/Lower. 6/18. 19/7. 0.001†. VFI. 67.83 ± 10.71. 68.23 ± 13.23. 0.763*. MD. -11.64 ± 2.62. -10.69 ± 3.54. 0.252*. PSD. 10.74 ± 5.85. 12.86 ± 2.61. 0.087*. V/A (logMAR) IOP (mmHg). Data are expressed as the mean ± standard deviation unless otherwise indicated. NAION = non-arteritic anterior ischemic optic neuropathy; NTG = normal tension glaucoma; V/A = visual acuity; logMAR = 

(11) @  

(12) J  @

(13) J 

(14)  

(15) 

(16)     !  

(17)  pattern standard deviation. * Mann-Whitney U test; †Chi-square test.. Journal of the Korean Glaucoma Society.

(18) ҋ਌़਼ളേ१३ӄ࠾଑Ә‫ֳפ‬ણઅࢅҁࣽ‫ز‬௖஬ਕघҽࡻӯ. 49. ‫ֳפ‬ણӶਁࣳ ࣛௐ ࠉ१ৡҿछ੸ 19৊, ടௐ ࠉ१ৡҿछ੸ 7৊. અഡ ୱઊ‫ ؘ‬৺ৼ੶֢, ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄӶӘ ીࣛ৊৒. ੶ܾ ࣛௐ/ടௐ ࠉ१ৡҿछઅ ࡻੰਁ‫ ڂ ؘ‬Ӷ ҁઅ ੭અഡ ୱઊ. ‫ֳפ‬ણӶઅ ೤ԑ १३ӄ੭‫ڂ‬ത߂ࡻ‫ ؘ‬ҀҀ 0.48 š 0.19, 0.81 š. ѿ ઔৼ‫(د‬p =0.001). ࡻ‫ޔٳ‬ਐऀ ৗളശ१३ӄ࠾଑ӶӘ ીࣛ৊. 0.06 (p <0.001), ೤ԑ १३ӄ੭‫ڂ‬౫޷હ੸ 1.40 š 0.32, 0.70 š. ৒‫ֳפ‬ણӶਁࣳ ೤ԑ‡

(19) ŠŒ!¨‹ˆ҈੸ ҀҀ 67.83 š. 0.14 (p <0.001)ܾ ‫ ڂ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ઔৼ‫د‬. ࡻ‫ޔٳ‬ਐ. 10.71, 68.12 š 13.23ઊৼӋ, ೤ԑ mean deviation (MD) ҈੸ Ҁ. ऀ ৗളേ१३ӄ࠾଑ӶӘ ીࣛ৊৒‫ֳפ‬ણӶਁࣳ ೤ԑ ੭‫૲ڂ‬. Ҁ -11.64 š 2.62, -10.69 š 3.54, ೤ԑ pattern standard deviation. ੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռ‫ ؘ‬ҀҀ 68.54 š 10.70, 66.62 š 9.30. (PSD) ҈੸ ҀҀ 10.74 š 5.85, 12.86 š 2.61ܾ ‫ ڂ‬Ӷ ҁઅ १ৡҩ. ੶ܾ ੭અഡ ୱઊ‫ ؘ‬৺ৼӋ, ࣛௐ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ. ࣏અ ଒೵‫ ؘ‬౿ӆહ੶ܾ ੭અഡ ୱઊѿ ৺ৼ‫(د‬Table 1).. ‫ڂ‬Ռ‫ ؘ‬ҀҀ 66.83 š 19.92, 79.35 š 19.11 (p =0.019), ടௐ੸ Ҁ. ࢅҁࣽ‫ز‬௖஬ਕ੹ ઊੋഡ १३ӄ੭‫ڂ‬અ Ӵ૒હઌ ࡚ࣴਁࣳ. Ҁ 96.38 š 27.46, 68.54 š 16.13 (p <0.001), ઊௐ੸ ҀҀ 49.63 š. ೤ԑ १३ӄ੭‫ڂ‬અ ޷હ੸ ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ӷઊ. 8.36, 58.35 š 13.62 (p =0.017)ܾ ‫ ڂ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ઔৼ. 1.97 š 0.33, ીࣛ৊৒‫ֳפ‬ણӶઊ 2.11 š 0.43੶ܾ ‫ ڂ‬Ӷ ҁઅ ੭. Ӌ, ࡻௐ੸ ҀҀ 57.88 š 8.60, 59.73 š 8.21ܾ ੭અഡ ୱઊ‫ࡂ ݴ‬. Table 2. Comparison of optic nerve head analysis and pRNFL parameters. NAION (n = 24). NTG (n = 26). p -value*. Disc area. 1.97 ± 0.33. 2.11 ± 0.43. 0.193. Average CDR. 0.48 ± 0.19. 0.81 ± 0.06. <0.001. 1.40 ± 0.32. 0.70 ± 0.14. <0.001. 68.54 ± 10.70. 66.62 ± 9.30. 0.953. Rim area Average pRNFL Superior. 66.83 ± 19.92. 79.35 ± 19.11. 0.019. Temporal. 49.63 ± 8.36. 58.35 ± 13.62. 0.017. Inferior. 96.38 ± 27.46. 68.54 ± 16.13. <0.001. Nasal. 57.88 ± 8.60. 59.73 ± 8.21. 0.599. Data are expressed as the mean ± standard deviation. "#$   '    &  ' #>#

(20) K       

(21)   

(22)   

(23)  '#?Q

(24)   

(25)  glaucoma; CDR = cup/disc ratio. * Mann-Whitney U-test. Table 3. Comparison of clockwise pRNFL parameters. NAION (n = 24). NTG (n = 26). p -value*. 12/12. 68.25 ± 19.62. 76.69 ± 24.34. 0.214. 1/11. 63.13 ± 13.38. 76.62 ± 18.92. 0.004. 2/10. 61.71 ± 13.56. 67.62 ± 11.01. 0.032. 3/9. 53.54 ± 8.62. 54.92 ± 9.26. 0.899. 4/8. 55.54 ± 8.06. 56.65 ± 10.87. 0.838. 5/7. 76.46 ± 20.82. 70.96 ± 13.12. 0.420. 6/6. 102.13 ± 35.60. 69.19 ± 20.27. <0.001. 7/5. 102.38 ± 39.51. 65.35 ± 24.41. <0.001. 8/4. 55.79 ± 13.88. 53.31 ± 16.29. 0.321. 9/3. 42.96 ± 8.38. 55.38 ± 14.83. 0.001. 10/2. 48.04 ± 12.22. 67.19 ± 20.60. 0.001. 11/1. 64.17 ± 17.48. 83.38 ± 30.24. 0.024. Data are expressed as the mean ± standard deviation. "#$   '    &  ' #>#

(26) K       

(27)   

(28)   

(29)  '#?Q

(30)   

(31)  glaucoma. * Mann-Whitney U-test.. www.koreanglaucoma.org.

(32) 50. JOURNAL OF THE KOREAN GLAUCOMA SOCIETY. 9ROXPH_1XPEHU. Table 4. Comparison of mGCIPL parameters. NAION (n = 24) Average mGCIPL. 65.79 ± 8.65. NTG (n = 26) 66.62 ± 9.78. p -value* 0.669. Superonasal. 63.92 ± 13.50. 74.96 ± 10.66. 0.003. Superior. 62.58 ± 11.66. 71.50 ± 11.01. 0.008. Superotemporal. 60.79 ± 8.65. 67.73 ± 11.58. 0.024. Inferotemporal. 70.00 ± 13.97. 58.69 ± 13.27. 0.008. Inferior. 69.71 ± 10.63. 58.38 ± 11.18. 0.002. Inferonasal. 66.67 ± 11.83. 68.04 ± 14.21. 0.899. Data are expressed as the mean ± standard deviation. mGCIPL = macular ganglion cell-inner plexiform layer; NAION = non-arteritic anterior ischemic optic neuropathy; NTG = normal tension glaucoma. * Mann-Whitney U-test. Table 5. Comparison of OCT parameters in patients with superior altitudinal visual field defect. Average pRNFL. NAION (n = 6). NTG (n = 19). p -value*. 70.83 ± 10.26. 66.84 ± 9.34. 0.926. 84.00 ± 10.81. 86.05 ± 16.89. 0.687. Temporal. 48.17 ± 9.50. 59.21 ± 13.48. 0.069. Inferior. 71.67 ± 3.78. 65.74 ± 9.93. 0.056. Nasal. 66.50 ± 7.61. 59.79 ± 7.79. 0.059. Average mGCIPL. 60.67 ± 7.45. 65.53 ± 9.15. 0.176. Superonasal. 64.17 ± 14.01. 74.79 ± 11.64. 0.092. Superior. 66.50 ± 12.52. 72.37 ± 11.84. 0.246. Superotemporal. 63.50 ± 10.89. 70.26 ± 11.58. 0.176. Inferotemporal. 52.83 ± 6.15. 54.68 ± 8.88. 0.598. Inferior. 56.67 ± 3.67. 55.47 ± 9.26. 0.828. Inferonasal. 55.33 ± 7.69. 65.37 ± 10.48. 0.049. Superior. Data are expressed as the mean ± standard deviation. OCT = optical coherence tomography; NAION = non-arteritic anterior ischemic optic neuropathy; NTG = normal tension glaucoma; "#$   '    &  ' QX$  @ @

(33)  K !J

(34)  ' + * Mann-Whitney U-test.. ઊ଒ ৌ৔‫(د‬Table 2). ‫ ڂ‬Ӷਁࣳ ௐીഡ १ӆ࡚઻ ੭‫૲ڂ‬੥ ‫ޏ‬. 69.71 š 10.63, 58.38 š 11.18 (p =0.002)ܾ ‫ ڂ‬Ӷ ҁઅ ੭અഡ ୱઊ. ‫ޅ‬३ӄࣼ੭௖અ ‫ڂ‬Ռ‫ ؘ‬1/11१(p =0.004), 2/10१(p =0.032), 6/6. ѿ ઔৼӋ, ടࡻௐ੸ ҀҀ 66.67 š 11.83, 68.04 š 14.21ܾ ੭અഡ. १(p <0.001), 7/5१(p <0.001), 9/3१(p =0.001), 10/2१(p =0.001),. ୱઊ‫ࡂ ݴ‬ઊ଒ ৌ৔‫(د‬Table 4).. 11/1१(p =0.024)ਁࣳ ੭અഡ ୱઊѿ ઔৼ‫(د‬Table 3).. ࣛௐ ࠉ१ৡҿछઊ ઔ‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑ 6৊Ә. ೤ԑ ൠࠉࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ޔٳࡻ ؘ‬ਐऀ. ીࣛ৊৒‫ֳפ‬ણ 19৊੹ ࡻӯയ੹ ‫ ڹ‬೤ԑ, ࣛௐ, ടௐ, ࡻௐ, ઊ. ৗളേ१३ӄ࠾଑Ӷਁࣳ 65.79 š 8.65, ીࣛ৊৒‫ֳפ‬ણӶਁ. ௐ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռਭ ೤ԑ ൠࠉࡘ ‫ޅޏ‬३ӄ઻. ࣳ 66.62 š 9.78ܾ ‫ ڂ‬Ӷ ҁઅ ੭અഡ ୱઊ‫ ؘ‬৺ৼ੶֢, ࡻ‫ޔٳ‬ਐ. ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ ڂ ؘ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ৺ৼ੶֢, ട. ऀ ৗളേ१३ӄ࠾଑ӶӘ ીࣛ৊৒‫ֳפ‬ણӶਁࣳ ࣛࡻௐ ൠࠉ. ࡻௐ ൠࠉࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռѿ ҀҀ 55.33 š. ࡘ ‫ޅޏ‬३ӄࣹं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ ؘ‬ҀҀ 63.92 š 13.50, 74.96. 7.69, 65.37 š 10.48ܾ ‫ ڂ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ઔৼ‫(د‬p =0.049). š 10.66 (p =0.003), ࣛௐ੸ ҀҀ 62.58 š 11.66, 71.50 š 11.01. (Table 5).. (p =0.008), ࣛઊௐ੸ ҀҀ 60.79 š 8.65, 67.73 š 11.58 (p =0.024),. ടௐ ࠉ१ৡҿछઊ ઔ‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑ 18৊. ടࡻௐ੸ ҀҀ 70.00 š 13.97, 58.69 š 13.27 (p =0.008, ടௐ੸. Ә ીࣛ৊৒‫ֳפ‬ણ 7৊੹ ࡻӯയ੹ ‫ ڹ‬೤ԑ, ࣛௐ, ടௐ, ࡻௐ, ઊ. Journal of the Korean Glaucoma Society.

(35) ҋ਌़਼ളേ१३ӄ࠾଑Ә‫ֳפ‬ણઅࢅҁࣽ‫ز‬௖஬ਕघҽࡻӯ. 51. Table 6. Comparison of OCT parameters in patients with inferior altitudinal visual field defect. Average pRNFL. NAION (n = 18). NTG (n = 7). p -value*. 67.78 ± 11.02. 66.00 ± 9.88. 0.790. Superior. 61.11 ± 9.89. 61.14 ± 11.67. 0.929. Temporal. 50.11 ± 8.19. 56.00 ± 14.80. 0.495. 104.61 ± 27.55. 87.00 ± 15.61. 0.110. 55.00 ± 6.93. 59.57 ± 9.91. 0.326. Average mGCIPL. 67.50 ± 8.51. 69.57 ± 11.54. 0.836. Superonasal. 63.83 ± 13.74. 75.43 ± 8.20. 0.034. Inferior Nasal. Superior. 61.28 ± 11.43. 69.14 ± 8.73. 0.125. Superotemporal. 59.89 ± 7.93. 60.86 ± 9.03. 0.790. Inferotemporal. 75.72 ± 10.69. 69.57 ± 17.55. 0.458. Inferior. 74.06 ± 8.30. 66.29 ± 12.79. 0.158. Inferonasal. 70.44 ± 10.56. 75.29 ± 20.70. 0.836. Data are expressed as the mean ± standard deviation. OCT = optical coherence tomography; NAION = non-arteritic anterior ischemic optic neuropathy; NTG = normal tension glaucoma; "#$   '    &  ' QX$  @ @

(36)  K !J

(37)  ' + * Mann-Whitney U-test.. ௐ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռਭ ೤ԑ ൠࠉࡘ ‫ޅޏ‬३ӄ. ࣼ੭௖અ ‫ڂ‬Ռ‫ ؘ‬ીࣛ৊৒‫ֳפ‬ણӶઊ ੭અടҲ ً ৥৔‫د‬. ട. ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ ڂ ؘ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ৺ৼ੶֢,. ଒‫ࠉ ކ‬१ৡҿछઅ ੥ௗਭ‫فࣛ ؘ‬હ੶ܾ Ӛӆѿ હ੸ ઊௐ ੭. ࣛࡻௐ ൠࠉࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռѿ ҀҀ 63.83. ‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռѿ ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾. š 13.74, 75.43 š 8.20੶ܾ ‫ ڂ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ઔৼ‫د‬. ଑Ӷਁࣳ ੭અടҲ ً ৥৔Ӌ, ઊ ҿӘ‫ؘ‬%  – 

(38) 1અ ਌. (p =0.034) (Table 6).. Ӵਭ٩ Ҏ৔‫د‬. Hood et al32ઊ ࠋ೵ഡ ਌Ӵਁ ‫ֳפ ޷ݱگ‬ણ ൝. 고찰. ણ ‫ؠ‬Ҳ छࣛ੹ ࠊ‫دؘ‬Ӌ ടਔӋ, Contreras et al11Ә Deleón-. ઘਁࣳ ઊௐ १३ӄ౫ ࠃ ઊௐ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖੸ ѿ Ortega et al12੸ ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑ ൝ઘਁࣳ ઊௐ ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑੸ ҇ઘԞ ࠋࣥട‫ߗ ؘ‬౿ऀઅ. ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռѿ ࠉ‫ف‬೟ਁ ࡻന ੭અടҲ. १ܲસട, १ৡણ৘ѿ ಡଛહઌ ଑ࣛઊ޵ १३ӄ੭‫ࡘڂ‬૚ઊ. ҆घയӋ ઊ‫ ؘ‬૝଒ ৌ੸ १ܲӘ ੭અഡ ࣛӚӚӆѿ ઔ‫د‬Ӌ ട. 27. ‫دټࠉٳ‬. १३ӄ੭‫ࡘڂ‬૚੸ १ҁઊ ଒़֧ܿ ઽୱ ҆घട. ਔ‫د‬. ࡅ ਌Ӵਁࣳ٩ ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ӷઅ ൝ઘ. Ҳ ‫ ޵ٻ‬ઊਁ ‫ ܅گ‬੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖Ә ൠࠉࡘ ३ӄ઻. ‫ڝ‬ઊ ીࣛ৊৒‫ֳפ‬ણӶਁ ࡻന १ܲઊ ૝଒ ৌৈ ઊਭ ‫੹܆ޔ‬. 28. ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ٩ ҆घടҲ ‫دټ‬. ࠉ޷ ીࣛ৊৒‫ֳפ‬. Ҏઊ ഡ‫د‬Ӌ ࡆ ़ ઔ‫د‬.. ણ੸ Ԟ‫؟‬હ छࣛઌ १ৡҿछઊ ֢ౌ֢Ԟਁ ৗࣳ Ӵ૒હ छࣛ. ‫୳ބ‬ѿ଒ܾ ࣛࡻௐ, ࣛௐ, ࣛઊௐ ൠࠉࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ. ઌ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ࠹൛ѿ ࣷര‫دټ‬Ӌ ্ܱ૊ ઔ. ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑Ӷઊ, ടࡻௐ,. 29–31. ઊ‫ܨ‬Ҳ ‫ ڂ‬ଖ൝અ ࠾ౖࣥ‫ݱد ؘݼ‬଒‫ࡻ ކ‬॥ഡ ޾৩અ. ടௐ, ടઊௐ ൠࠉࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ ؘ‬ીࣛ. ࠉ१ৡҿछઊ ֢ౌ֧ ़ ઔৰ ࢅҁࣽ‫ز‬௖஬ਕ੹ ઊੋന ‫ ڂ‬ଖ. ৊৒‫ֳפ‬ણӶઊ ੭અടҲ ً ৥৔‫د‬. ઊ‫ ݴ‬Ҏ੸ ૒ҥਁࣳ ࡻӯ. ൝ਁࣳ ֢ౌ֢‫ ؘ‬१३ӄӘ ൠࠉࡘઅ Ӵ૒હઌ ୱઊ‫্ ݴ‬ৈࡂ. ടԞ ੥ന ࠉ१ৡҿछઅ ੥ௗѿ Ҏ੸ ൝ઘ‫ ݼ֚ڝ‬ൠࠉࡘ ‫ޅޏ‬. ‫د‬.. 1,4,6,21,22. ܱ ഡ ਉ‫ ܟ‬਌Ӵ‫ڝ‬ઊ ࠋ೵‫ٻ‬Ӌ ઔ‫د‬.. ३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ࡻ ݴ‬ӯടਔӋ ࣛௐ ࠉ१ৡҿछ. ࡅ ਌Ӵਁࣳ ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ӷਁࣳ‫ ؘ‬ടௐ ࠉ. ઊ ઔ‫ ؘ‬ӄੌ‫ ؘ‬ടࡻௐਁࣳ, ടௐ ࠉ१ৡҿछઊ ઔ‫ ؘ‬ӄੌ‫ؘ‬. १ৡҿछઊ ‫އ‬৔Ӌ(18৊/24৊), ીࣛ৊৒‫ֳפ‬ણӶਁࣳ‫ࣛ ؘ‬ௐ. ࣛࡻௐਁࣳ ‫ ڂ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ઔৼ‫د‬. ‫ࡻ ࣳ܅گ‬ௐ ൠ. ࠉ१ৡҿछઊ ً ‫އ‬৔‫(د‬19৊/26৊). ઊ‫ ؘ‬ઊ઺ ਌Ӵਭ٩ Ҏ੸. ࠉࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռѿ ીࣛ৊৒‫ֳפ‬ણӶਁ. 1,6. ‫ࣛ ࣳ܅گ‬ௐ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռ‫ؘ‬. ࡻന ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ӷਁࣳ ੭અടҲ ৥৔‫د‬Ӌ. ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ࠾଑Ӷઊ, ടௐ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄ. ഢ ़ ઔৼ‫د‬. Yang et al15ਁ અട޷ ‫މ‬Ԟ ‫ֳפ‬ણ੶ܾ ଔരഢ. ҿӘਔӋ. www.koreanglaucoma.org.

(39) 52. JOURNAL OF THE KOREAN GLAUCOMA SOCIETY. ‫ڹ‬Ԫ଒٩ ൠࠉࡘઅ ࡻௐ੸ ‫ޅޏ‬३ӄ઻ं೩ѿ ৰ‫ ؖ‬ી٩ ࡂ૔. 9ROXPH_1XPEHU. References. 33. ‫دټ‬Ӌ ടਔӋ, Weber et al અ ਌Ӵਁࣳ‫ ؘ‬ઊௐ ੭‫૲ڂ‬੥ ‫ޏ‬ ‫ޅ‬३ӄࣼ੭௖Ә തՌ ࡻௐ ൠࠉࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖ઊ. —'%  –$‹ –Ÿ=‡ @

(40) ‘© 

(41) '•

(42) -. ‫ֳפ‬ણ੹ ଔ‫ز‬ട‫ ؘ‬ٙ ઔৰࣳ ѿણ ଔ‫ز‬હ ѿௗѿ હ‫د‬Ӌ ടਔ.  ‡ 

(43)  

(44)  „Š„  . ‫د‬. ࡅ ਌Ӵਁࣳ٩ ઊ‫ࠊڒ ݴ‬௝ട‫ ؘ‬ҿӘѿ ֢ਢ ҫ੶ܾ ࣥҀ ‫دټ‬.. non-arteritic anterior ischemic optic neuropathy and „  

(45) 

(46) 'Z

(47) = •‘Œ‰

(48)  2010;248:845-51.. १३ӄ੭‫ڂ‬અ Ӵ૒હઌ ࡚ࣴਁࣳ‫ ؘ‬Han et al6અ ਌Ӵਭ ‫୳ބ‬. 2. Saito H, Tomidokoro A, Sugimoto E, et al. Optic disc to-. ѿ଒ܾ १३ӄ੭‫ڂ‬અ ޷હ੸ ‫ ڂ‬Ӷ ҁઅ ੭અഡ ୱઊѿ ৺ৼ଒. 

(49)  „

(50) 

(51) 

(52) „ 

(53) ‡Š

(54) „ -. ‫ކ‬, १३ӄ੭‫ ڂ‬ത߂ࡻ ࠃ १३ӄ౫અ ޷હ੸ ‫ ڂ‬Ӷ ҁઅ ੭અ. ness in nonarteritic ischemic optic neuropathy and open-. ഡ ୱઊѿ ઔৼ‫د‬. ઊ‫ ؘ‬१३ӄ੭‫ ڂ‬ത߂ࡻѿ ઙ੹़ܿ ളേਁ. angle glaucoma. Ophthalmology 2006;113:1340-4.. ௃ৢട‫ ؘد‬Ԟ૔અ ਌ӴҿӘਭ٩ ઍௗയ‫د‬.34. 3. Danesh-Meyer HV, Boland MV, Savino PJ, et al. Optic  „Ÿ

(55) 

(56) 

(57) 

(58)   . ࡅ ਌Ӵѿ Ԟ૔અ ਌Ӵਭ ‫ ݳد‬ઽ੸ ࢅҁࣽ‫ز‬௖஬ਕઅ ଒೵ ܾ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖Ә ൠࠉࡘ ‫ޅޏ‬३ӄ઻ஔ೩-ֳ‫ޏ‬ 1. ࣛ௖અ ‫ڂ‬Ռ‫ࡻ ݴ‬ӯയ‫ ؘد‬ҫઊ‫'د‬%  – 

(59)  Ә Han et 6. al અ ਌Ӵਁࣳ‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ‫ֳפ‬ણ ൝ઘ ਁࣳ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄࣼ੭௖અ ‫ڂ‬Ռ‫ࡻ ݴ‬ӯയ଒‫ ކ‬ൠࠉࡘ. anterior ischemic optic neuropathies. Invest Ophthalmol Vis Sci 2010;51:2003-10. 4. Fard MA, Afzali M, Abdi P, et al. Comparison of the pattern of macular ganglion cell-inner plexiform layer defect    

(60) „

(61) Ÿ

(62) 

(63) coma. Invest Ophthalmol Vis Sci 2016;57:1011-6.. ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ ؘ‬ௐીട଒ ৌ৔Ӌ, ‫ֳפ‬ણ. 5. Choi JA, Park HY, Jung KI, et al. Difference in the proper-. Ӷ੹ ґࠒҀ‫ֳפ‬ણ੶ܾ ીઅന ࡅ ਌Ӵਭ ୱઊѿ ઔৼ‫د‬. ۙഡ.  

(64) ‡Š

(65) „  

(66) . ࡅ ਌Ӵ‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ൝. ‡

(67) Š

(68) 

(69) 'ˆ‡ ‰

(70) . ઘ‫ࠉ ૻ ڝ‬१ৡҿछ੹ ѿଔ ൝ઘ‫ૂ ੹ࣛف ܾڝ‬ഡയӋ, ൠࠉ. Vis Sci 2013;54:6982-90.. ࡘ ‫ޅޏ‬३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռ‫ࡻ ݴ‬ӯഢ ‫ ؘڹ‬Ԟ૔ ਌Ӵ ਭ‫ ݼش ؘ‬१ৡҿछઅ ੥ௗѿ Ҏ੸ ൝ઘ‫ࡻ ݼ֚ڝ‬ӯടਉ ҿӘ અ ౌ‫׬ ੹ऀؽ‬ਔ‫د‬Ӌ ഢ ़ ઔ‫د‬.. ˜'%

(71) $$$²'‚ Ÿ

(72)    anterior ischemic optic neuropathy and open angle glau

(73)   

(74)   

(75) ‡

(76)  '

(77) $‰ thalmol 2015;29:418-23.. ࡅ ਌Ӵઅ ૂഡઽ੸, ൝ઘ‫ڝ‬ઊ Ԟ૔ਁ ѿ଒Ӌ ઔَ ઺३હઌ. 7. Schuman JS, Hee MR, Arya AV, et al. Optical coherence. ଖ൝੹ Ӌܱട଒ ৌৈ १ৡҩ࣏֢ ࢅҁࣽ‫ز‬௖஬ਕઅ ҿӘਁ. 

(78)  „

(79)      

(80) 

(81)  

(82) ' •. ਠ‫ݩ‬ѿ ࠋࣥടਔ੹ ѿ‫ऀ؟‬ઊ ઔ‫ ؘد‬ઽઊ‫د‬. ۙഡ ‫ࣛف‬ઘઅ ़ ѿ હৰ ࢅҁࣽ‫ز‬௖஬ਕઅ ҿӘ‫ࡻ ݴ‬ӯഢ ‫ ڹ‬౿ӆહ ࡚ࣴਁ ഡ ӆѿ ઔৼӋ, ‫ࣛف‬ઘ‫़ ݴ‬ીஔ৊੶ܾ‫ૂ ކ‬ഡട଒ ৌৈ १ৡҩ. Opin Ophthalmol 1995;6:89-95. 8. Hood DC, Anderson SC, Wall M, Kardon RH. Structure versus function in glaucoma: an application of a linear model. Invest Ophthalmol Vis Sci 2007;48:3662-8.. ࣏ ҿӘਁ ਕല੹ ߸௛ ़ ઔৼ‫د‬. ԓ‫ݼ‬Ӌ ીࣛ৊৒‫ֳפ‬ણ൝ઘ. ›'%‚•

(83) @%'=

(84)  

(85)  -. અ ӄੌ ࣏ੋ ૻઌ ‫ֳפ‬ણ ৊ৢઅ ґ़‫ ݴ‬Ӌܱട଒ ߆യ‫د‬. ஷ. tural and functional measures of glaucomatous damage.. ൲ ઊ‫ܟ‬ഡ ઽ੹ ࡂਯഡ ਌Ӵ‫ ݴ‬౿ന ࡻ‫ޔٳ‬ਐऀ ৗളേ१३ӄ ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણਁࣳ १३ӄઅ Ӵ૒હ ୱઊਁ ‫ف‬ഡ ૗ ً ೪‫࡚ࣴ ੸׈‬ઊ ച੄ഢ ҫઊ‫د‬. ҿ݀હ੶ܾ, ࠉ१ৡҿछ੹ ѿ଒‫ޔٳࡻ ؘ‬ਐऀ ৗളേ१३. Prog Retin Eye Res 2007;26:688-710. 10. Contreras I, Rebolleda G, Noval S, Muñoz-Negrete FJ. Optic disc evaluation by optical coherence tomography in nonarteritic anterior ischemic optic neuropathy. Invest Ophthalmol Vis Sci 2007;48:4087-92.. ӄ࠾଑Ә ીࣛ৊৒‫ֳפ‬ણ ൝ઘਁࣳ ઊௐ ੭‫૲ڂ‬੥ ‫ޅޏ‬३ӄ. 11. Contreras I, Noval S, Rebolleda G, Muñoz-Negrete FJ.. ࣼ੭௖Ә ࡻௐ ൠࠉࡘ ३ӄ઻ं೩-ֳ‫ࣛޏ‬௖અ ‫ڂ‬Ռਁ ੭અഡ. ‹ Ÿ

(86)   

(87)    

(88) -. ୱઊѿ ઔ੻੹ ্ ़ ઔৼ‫د‬. ‫ ڂ ࣳ܅گ‬ଖ൝੹ ҆࠺ഢ ‫ ڹ‬ઊ. „    

(89)    

(90)  „' ‰

(91) „. ਭ Ҏ੸ ࢅҁࣽ‫ز‬௖஬ਕ ҿӘѿ ٩੒ઊ ‫ ़ ٽ‬ઔ੹ ҫઊ‫د‬.. 2007;114:2338-44. 12. Deleón-Ortega J, Carroll KE, Arthur SN, Girkin CA. Cor

(92)   

(93) ‡Š

(94) „

(95) ‡

(96) Š „  

(97)   

(98)    

(99) thy. Am J Ophthalmol 2007;143:288-94.. Journal of the Korean Glaucoma Society.

(100) ҋ਌़਼ളേ१३ӄ࠾଑Ә‫ֳפ‬ણઅࢅҁࣽ‫ز‬௖஬ਕघҽࡻӯ. 53. 13. Jeoung JW, Choi YJ, Park KH, Kim DM. Macular gan-. \\'#‘$• &$  %

(101) $'•

(102)  . glion cell imaging study: glaucoma diagnostic accuracy.  ‡ 

(103)    

(104) Ÿ . of spectral-domain optical coherence tomography. Invest. glaucoma and nonarteritic anterior ischemic optic neu-. Ophthalmol Vis Sci 2013;54:4422-9.. ropathy. PLoS One 2016;11:e0150242.. —Q'

(105)

(106)  $• ‚  >– ‚#  

(107) ' Z

(108) 

(109) . 23. Hong EH, Shin YU, Lim HW, et al. RNFL and ganglion. diagnostic accuracy of ganglion cell-inner plexiform layer. cell complex thickness in normal hemifield according.  

(110)    ‡  

(111) „

(112)   . to the severity of glaucoma. J Korean Ophthalmol Soc. nerve head. Ophthalmology 2012;119:1151-8.. 2016;57:614-22.. 15. Yang Z, Tatham AJ, Weinreb RN, et al. Diagnostic. \Q'

(113) $ „‘'•

(114)  ‡

(115) 

(116)  „

(117) . ability of macular ganglion cell inner plexiform layer.  

(118) ‡Š

(119) „  

(120) '$. 

(121)  

(122) 

(123)   

(124) tral domain optical coherence tomography. PLoS One 2015;10:e0125957. 16. Tan O, Chopra V, Lu AT, et al. Detection of macular ganglion cell loss in glaucoma by Fourier-domain optical coherence tomography. Ophthalmology 2009;116:2305-14. e1-2. —ž'=

(125) 

(126)  ‚

(127)  ‰ %

(128)  ‚ 

(129) ==' 

(130)  . Korean Ophthalmol Soc 2016;57:628-33. 25. Choi BS, Jang SG, Shin JH, Lee JW. Retinal Nerve Fiber #

(131) „  

(132)     ‚   

(133)  Domain Optical Coherence Tomography Devices. J Korean Ophthalmol Soc 2016;57:1118-25. 26. Lee J, Park JM. Analysis of ganglion cell-Inner plexiform layer thickness after internal limiting membrane peeling. J Korean Ophthalmol Soc 2016;57:1369-77.. 

(134) Œ

(135) ‡Š

(136) „-. 27. Beri M, Klugman MR, Kohler JA, Hayreh SS. Anterior. arteritic ischemic optic neuropathy by Fourier-domain. ischemic optic neuropathy. VII. Incidence of bilateral-. optical coherence tomography. Invest Ophthalmol Vis Sci. ity and various influencing factors. Ophthalmology. 2012;53:4539-45.. 1987;94:1020-8.. 18. Gonul S, Koktekir BE, Bakbak B, Gedik S. Comparison. 28. Goto K, Miki A, Araki S, et al. Time course of macular.  

(137) Œ

(138)  

(139) ‡Š

(140) „. and peripapillary inner retinal thickness in non-arteritic. measurements using Fourier domain optical coherence. anterior ischaemic optic neuropathy using spectral-domain. tomography to detect ganglion cell loss in non-arteritic. optical coherence tomography. Neuroophthalmology. anterior ischaemic optic neuropathy. Br J Ophthalmol 2013;97:1045-50. 19. Larrea BA, Iztueta MG, Indart LM, Alday NM. Early axonal damage detection by ganglion cell complex analysis. 2016;40:74-85. 29. Sommer A, Katz J, Quigley HA, et al. Clinically detect

(141) ‡Š

(142)  „  

(143) 

(144) Š'= ‰

(145) —››—«—^›žžŸ™'.   

(146)   

(147)  „

(148)   

(149)  . 30. Quigley HA, Katz J, Derick RJ, et al. An evaluation of op-. ischaemic optic neuropathy. Graefes Arch Clin Exp Oph-. 

(150) ‡Š

(151) „Œ

(152) 

(153)  . thalmol 2014;252:1839-46.. progression of early glaucoma damage. Ophthalmology. 20. Rebolleda G, Sánchez-Sánchez C, González-López JJ, et al. Papillomacular bundle and inner retinal thick

(154)   ‡

(155) 

(156)  „

(157)   

(158)   ischemic optic neuropathy. Invest Ophthalmol Vis Sci 2015;56:682-92. 21. Suh MH, Kim SH, Park KH, et al. Comparison of the 

(159)       

(160) 

(161) 

(162)   

(163)  nerve fiber layer thickness in glaucoma and nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol 2011;151:277-86.e1.. www.koreanglaucoma.org. 1992;99:19-28. ™—'©„ Z•

(164) $'

(165) Š

(166) age in early glaucoma. Arch Ophthalmol 1993;111:62-5. 32. Hood DC, Raza AS, de Moraes CG, et al. Glaucomatous damage of the macula. Prog Retin Eye Res 2013;32:1-21. 33. Weber J, Schultze T, Ulrich H. The visual field in advanced glaucoma. Int Ophthalmol 1989;13:47-50. 34. Doro S, Lessell S. Cup-disc ratio and ischemic optic neuropathy. Arch Ophthalmol 1985;103:1143-4..

(167)

참조

관련 문서

Preoperative evaluation of pelvic lateral lymph node of patients with lower rectal cancer: comparison study of MR imaging and CT in 53 patients?.

The total charge density from the metal surface and specifically adsorbed anions in inner layer is equal to the charge from solvated ions in diffuse layer. σ metal + σ inner =

Comparison of clinical risk factors and distribution of age, sex of patients aged ≧80 years and &lt;80 years... Comparison of the stroke subtype and thrombolysis of

In this study, the expression profiles of miRNAs were compared and analyzed for establishment of miRNAs related cancer cell growth inhibition in normal human oral

Objective: The purpose of this study was to analyze recent trend in incidence of basal cell carcinoma and squamous cell carcinoma in patients from the Gwangju City

Actinic keratoses showed a trend towards increased expression in the basal layer compared with normal skin.. In actinic keratoses, Keratoacanthomas and seborrheic

Comparison of mean and standard deviation of capnographic I:E ratio between normal breathing status and respiratory depression status in 21 patients experienced

The double heterostructure of the non-phosphor white LED was composed of Te-doped AlGaN as n-cladding layer, AlGaN as active layer, Mg-doped AlGaN as p-cladding layer,