The Clinical Effects of Carthami-Flos Pharmacopuncture on Posterior Neck pain of Menopausal Women

The Clinical Effects of Carthami-Flos Pharmacopuncture on Posterior Neck pain of Menopausal Women

Jae-Yeon Park*, Kyung-Jin Yun*, You-Jin Choi**, Min-Seok Kim**, Sung-Jin Yu***, Cham-Kyul Lee*, Jeong-Du Roh** and Eun-Yong Lee*

Department of Acupuncture & Moxibustion, Semyung University oriental medicine hospital, Chungju, Korea*

Department of Acupuncture & Moxibustion, Semyung University oriental medicine hospital, Jecheon, Korea**

Department of Oriental Gynecology, Semyung University oriental medicine hospital, Chungju, Korea***

KEY WORDS:

Carthami-Flos; Neck pain,

Pharmacopuncture;

menopause; VAS; NDI;

MENQOL.

Received : Nov 10, 2011 Revised : Nov 25, 2011 Accepted : Nov 30, 2011

I

48-49

Abstract

Objectives: The purpose of this research was to examine the effect of Carthami-Flos Pharmacopuncture on posterior neck pain of menopausal women.

Methods: We treated 20 female patients with neck pain patient(45-60 yr) into two groups and treated Group A with Carthami-Flos Pharmacopuncture and common acupuncture and Group B with common acupuncture. The efficacy of treatment was measured by VAS, NDI and MENQOL scores of before and after 30 days to start treatment.

Results: Both group A and B represented effective improvement in VAS and NDI of neck pain and MENQOL scores. And group A was more effective than B group statistically.

Conclusions: It was suggested that Carthami-Flos Pharmacopuncture treatment might have effect on posterior neck pain treatment of menopausal women.

Case Report

갱년기 여성의 경항통에 대한 홍화 약침 치료의 임상적 고찰

2011 Korean Pharmacopuncture institute http://pharmacopuncture.co.kr

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://cre- ativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non- commercial use, distribution, and reproduction in any medium, provid- ed the original work is properly cited.

Corresponding Author

Eun-Yong Lee, Department of Acupuncture & Moxibustion, Semyung University oriental medicine hospital, Bongbang-Dong 836, Chungju 380-080, Korea

Tel: +82-43-841-1735 E-mail: [email protected].

cc

(Carthami-Flos CF)

CF

2010 12 1 2011 5 30

40-60

CF

II

1

2010 12 1 2011 5 30

45 60

20

2

1 20

10 (Group A) 10 (Group B)

3

45 60

5

6

4

Korea

3

3 (8 ,

0.45 , 0.2

5

5.1

1

5.2

Syringe 1 Syringe(1.0 ,

26gauge Korea)

0.30mm 40mm

10-30mm

5.3

5.3.1 (Group A

A )

2 1 1

(GB

) (GB

)

CF 0.05

0.2 1 1 1

(GV

) (GV

) (BL

) (BL

) (GB

) (GB

) (SI

)

5.3.2 Group B B

1 1 1

(GV

) (GV

) (BL

) (BL

) (GB

) (GB

) (SI

)

5.4

Hot pack, TENS, ICT 6 10

5.5

2 3

6

6.1

1

6.2

6.2.1 (Visual analog scale, VAS)

0 10

6.2.2 Neck Disability index (NDI)

10 6

0-5 NDI

1

6.2.3 Menopause-specific quality of life ques- tionnaire (MENQOL)

The menopause-specific quality of life question- naire(MENQOL) Hildich 1992 Kupper- man's index

4

Vasomotor - 1~3 3 Psychosocial 4~10 7 Physical - 11~26(16 Sexual - 27~29 3

MENQOL

(Subscale) 1-8

1 0 2 6 8 4

subscale overall subscale score overall subscale score

2

6.3

A B 30 VAS, NDI MENQOL

VAS, NDI MEN- QOL

7

SPSS(Statistical program for Social Science) Ver 12.0 for window Mann- Whitney U-test

(Pearson`s chisquare test) Wilcoxon signed rank test

0.05

III

1.

1.1

A B 10

51.7 5.86 52.4 3.83 A

3 (30.0%) 1-2 3

(30.0%) 3-5 4 (40.0%)

B 3 (20.0%)

1-2 4 (40.0%) 3-5

3 (30.0%) (Table 1)

1.2

36.4 10.13 33.3

5.92 (Table 1)

2.

2.1 VAS, NDI, MENQOL 30 VAS, NDI, MENQOL

A Z-score VAS -2.829 NDI

-2.810, MENQOL -2.805 B Z-

score VAS -2.831, NDI -2.840, MEN-

QOL -2.807 VAS, NDI, MENQOL

(Table 2, Fig. 1-3)

Group A Group B p-value 51.7 5.86

36.4 10.13

52.4 3.83

33.3 5.92

0.440

0.647

Duration of

menopause (yr)

0 1-2 3-5

3(30.0) 3(30.0) 4(40.0)

3(30.0) 4(40.0) 3(30.0)

0.867

Table 1. Distribution of Patients

Mean Age Mean Days after on set

Group A: Carthami-Flos Pharmacopuncture and Common acupuncture group

Group B: Common acupuncture group 1): Mean standard deviation

2): Pearson`s chi-squared test

Group A

Group B

VAS

NDI MENQOL

-2.829**

-2.810**

-2.805**

-2.831**

-2.840**

-2.807**

Table 2. The Change of VAS, NDI and MENQOL in Each Group

Group A: Carthami-Flos Pharmacopuncture and Common acupuncture group

Group B: Common acupuncture group 1): Z-score in Wilcoxon signed rank test

** : Wilcoxon signed rank test p 0.05

2.2 VAS, NDI, MENQOL 30

VAS

P-value 0.029, NDI 0.007, MEN-

QOL 0.000

(Table 3, Fig. 4, 5)

Fig. 1. The Change of VAS on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture Group A: Carthami-Flos Pharmacopuncture and Common

acupuncture group

Group B: Common acupuncture group

** : Wilcoxon signed rank test p 0.05

Fig. 2. The Change of NDI on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture Group A: Carthami-Flos Pharmacopuncture and Common

acupuncture group

Group B: Common acupuncture group

** : Wilcoxon signed rank test p 0.05

Fig. 3. The Change of MENQOL on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture Group A: Carthami-Flos Pharmacopuncture and Common

acupuncture group

Group B: Common acupuncture group

** : Wilcoxon signed rank test p 0.05

Group A

Group B

p-value VAS

NDI MENQOL

7.2 1.13*

14.90 3.34**

1.39 0.16***

5.70 1.49 11.10 1.72

0.93 0.16

0.029 0.007 0.000 Table 3. Comparisoin of VAS, NDI and MENQOL

Improvement

Group A: Carthami-Flos Pharmacopuncture and Common acupuncture group

Group B: Common acupuncture group 1) Mean standard deviation

* : Mann-Whitney U-test p 0.05

** : Mann-Whitney U-test p 0.01

*** : Mann-Whitney U-test p 0.001

Fig. 4. Comparisoin of VAS and NDI Improvement on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture

Group A: Carthami-Flos Pharmacopuncture and Common acupuncture group

Group B: Common acupuncture group

* : Mann-Whitney U-test p 0.05

** : Mann-Whitney U-test p 0.01

IV

3-6

(Cervical spondy- losis)

Fig. 5. Comparisoin of MENQOL Improvement on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture

Group A: Carthami-Flos Pharmacopuncture and Common acupuncture group

Group B: Common acupuncture group

*** : Mann-Whitney U-test p 0.001

Carthami-Flos CF

CF

(GB

)

(GB

) CF

2010 12 1 2011 5

30

CF 10 A

10 B

A B 51.7 5.86 52.4

3.83

36.4 10.13 33.3 5.92

A 4 (40.0%)

3 (30.0%) 3 (30.0%) B

2 (20.0%) 3 (30.0%) 1

(10.0%) 1 (10.0%) 3

(30.0%) (Table 1)

A VAS, NDI, MEN- QOL Z-score -2.829, -2.810, -2.805, B VAS, NDI, MENQOL Z-score -2.831, - 2.840, -2.807

(Table 2, Fig. 1-3)

A B VAS

P-value 0.029, NDI 0.007,

MENQOL 0.000

(Table 3, Fig. 4, 5)

CF

CF

CF

V

2010 12 1 2011 5 30

CF 10

A 10 B

1. (VAS), Neck Disability index (NDI) Menopause-specific quality of life ques- tionnaire (MENQOL) A B

2. A B A B

References

1. Lee JH et al. A Study on Climacteric Symp- toms in Korean Midlife Women. The Journal of Korean menopause. 2000; 6(2):142-56.

2. Lee JA et al. Relation of Lifestyle Factors to

Menopausal Symptoms and Management of

Middle-aged Women in Rural Area. The Jour-

nal of Korean Maternal and Child Health.

2001;5(1):83-96.

3. Choi JE et al. The Clinical Analysis of the Symptoms and Characteristics on 50 Cases of Postmenopause syndromes. The Journal of Oriental Obstetrics and Gynaecology.

2002;15(2):144-54.

4. Chinese Medicine Institute. The unabridged dictionary of Chinese medicine. Beijing: Ren- minweishengchuban. 1995:1458.

5. Yoon TS, Moon JH, Shin JS. Comprehensive Rehabilitation Approach to Cervical Radicu- loputhy. The Journal of Oriental Rehabilitation Medicine. 1987;11(2):130-9.

6. Korean Orthopaedic Association. Orthopae- dics. Seoul: Newest Medicine. 2006:583-4.

7. Korean Academy of Oriental Rehabilitation Medicine. Oriental Rehabilitation Medicine.

Seoul: Gunja. 2003:70-1.

8. Korean Acupuncture and Moxibustion Society.

Acupuncture and Moxibustion. Paju: Jipmun- dang. 2008:59, 63-5.

9. Korean Pharmacopuncture Institute.

Phamacopuncturology. Seoul: Elsevier Korea.

2008:1, 6-8, 134-5, 234-6.

10. The Korea Association of Herbology profes- sors. Herbology. Seoul: Younglimsa.

1998:424-5.

11. Kim HE et al. The clinical effect of Carthami- Flos Herbal Acupuncture in neck pain due to Soft tissue damage. The Journal of Korean Acupuncture and Moxibustion Society.

2002;19(4):112-23.

12. Chang SY et al. The clinical study of Herbal Acupuncture for neck pain caused by whiplash injury. The Journal of Korean Acupuncture and Moxibustion Society. 2007;24(4):35-41.

13. Huang YL, Lee CH, Yook TH. Effects of Semen Carthamus Tinctorius L.Aqua-acupunc- ture on the Experimental Osteoporosis. The Journal of Korean Acupuncture and Moxibus- tion Society. 1999;16(1):485-95.

14. Yang SI, Kim KS. A clinical study of two

patient with oligomenorrhea treated Carthmi flos of Aqua-acupuncture. Journal of Pharma- copuncture. 2005;8(3):107-13.

15. Heo SY. Assessment of Pain in Patients with Low Back Pain. The Journal of East-West Medicine. 1999;24(3):17-29.

16. Song KJ et al. Cross-Cultural Adaptation and Validation of the Korean Version of the Neck Disability Index. The Journal of Korean Orthopaedic Association. 2009;44(3):350-9.

17. Hildich JR et al. A menopause-specific quality of life questionnaire: development and psycho- metric properties. Maturitas. 1996;24(3):161-75.

18. Choi YD et al. The New Clinincal Obstetrics and Gynaecology. Seoul: Goryeo Medicine.

2001:305-26.

19. The Society of Oriental Obstetrics and Gynae- cology. Oriental Obstetrics and Gynaecology.

Seoul: Jungdam. 2002:222-48.

20. The Korean Society of Menopause. The Management of Menopause Woman. Seoul:

Calvin books. 1994:1, 3-7, 8-17, 27-36, 47-56, 60-3, 69-79.

21. Lee TG. A Study on treatment about neuromy- opathic symptoms of climacteric syndrome.

The Journal of Oriental Obstetrics and Gynaecology. 2001; 14(2):196-203.

22. Rene Cailliet. Park LJ. Soft Tissue Pain and Disability. Seoul: Jungdam. 1996:63-71.

23. Jeon JG, Lee HI. The Clinical Effects of Posterior Neck pain. The Journal of East-West Medicine. 1998;23(1):31-41.

24. Bogduk N. Regional musculoskeletal pain The neck. Baillieres Best Practice and Research.

Clinical Rheumatology. 1999;13(2):261-85.

25. Korean Society of Oriental Rehabilitation Medicine Professors. Oriental Rehabilitation Medicine. Seoul :Sewondang. 1995:281-306.

26. Yang SW, Jang JB. An investigation of litera- tures about menopausal disorders in oriental medicine. Kyung Hee Medicine.

2001;17(1):49-57.

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