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HR-1 Mice: A New Inflammatory Acne Mouse Model

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Table 1. Histochemical analysis and immunohistochemical profiling of the four mouse strains
Fig. 1. Two weeks after injection with 10 8  colony forming unit/μl  Propionibacterium acnes suspension, clinical inflammation was  significantly more prominent of HR-1 mice than the three other strains
Fig. 2. Injected HR-1 mice exhibited significantly greater epidermal thickening than BALB/c mice
Fig. 4. Integrin  α6 expression was significantly higher in the lower epidermis of injected HR-1 mice (particularly at 10 9  CFU/μl)  than the other three mouse strains (staining method: H&E)
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