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Controlling of the Arterial Blood Pressure Reduces Sig- nifi cantly the Target Organs Damage

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WCIM 2014 SEOUL KOREA 67

Poster Session

The Korean Journal of Internal Medicine Vol. 29, No. 5 (Suppl. 1)

PS 0081 Cardiology

Controlling of the Arterial Blood Pressure Reduces Sig- nifi cantly the Target Organs Damage

Yasser HESSEIN ABDOU1 Valdepenas Hospital, Spain1

Arterial hypertension can be associated with asymptomatic clinical conditions or end organ damage manifestation mainly with cardiac, renal, cerebral and peripheral vascu- lar diseases. Refractory hypertension is characterized by a maintained blood pressure of 140/90 mmHg or more with three antihypertensive drugs including diuretics.

Aim Of The Study: To determine whether the target organ damage is different from patient with refractory hypertension in comparison with well-controlled hypertensive patients in a hospital hypertension unite. MATERIAL Y METHODOS: Hypertensive patients treated with three or more antihypertensive drugs including a diuretic, were classifi ed into two groups: RHBP: patients with blood pressure (BP)>140 and /or90 mmHg in the last two visits; and HTAC group: patients with BP<140 and 90 mmHg in the last two visits. It was determined: fasting glucose, lipid profi le, uric acid, serum creatinine, creatinine clearance and microalbuminuria. Fundus, echocardiography,elec- trocardiogram and ambulatory blood pressure monitoring. Results: :62 patients were included in the study, 38 in the refractory group.The media of the ambulatory blood pressure monitoring was 146±8/87±11 mmHg in the refractory group versus 121±4/74±5 mmHg). in the controlled group(p=0.001).Target organ damage,the prev- alence of LVH was 76% in the refractory group versus 29% in the controlled group (p=0.001).The prevalence of albumin in24hours=30 mg/24 hours was 26.3 in the re- fractory group and4.2% in the controlled group (p=0.026)Eye fundus examinations, in the refractory group89.5% had grade II and 10% had grade III. In the controlled group 12.5% had normal fundus examinations and 87.5 had grade II (p=0.001).

Conclusions: Upon entry into the Unit, HTAr patients had similar levels of PA patients with HTAc, but have a signifi cantly increased cardiovascular risk. The prevalence of cardiovascular disease and organ damage cardiac renal and cerebral was signifi cantly higher in the refractory group than that of the controlled group.

PS 0083 Cardiology

Giant Saphenous Vein Graft Aneurysm: A Rare Cause of Hilar Mass

Zhen-Yu LIAO1, Ming-Jen LU1,2, Kou-Gi SHYU1,4, Huey-Ming LO1,3, Jun-Jack CHENG1, Chiung-Zuan CHIU1,3

Division of Cardiology, Shin Kong Wu Ho-Su Memorial Hospital, Taiwan R.O.C1, Division of Cardiovas- cular Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Taiwan R.O.C2, School of Medicine, College of Medicine, Fu-Jen Catholic University, Taiwan R.O.C3, Graduate Institute of Clinical Medicine, Taipei Medical University, Taiwan R.O.C4

Aneurysm of a saphenous vein graft (SVG) is a rare but fatal complication of coronary artery bypass graft (CABG) surgery. This anomaly may mimic atypical mediastinal mass by chest plain fi lm from the fi rst look. The development of saphenous vein graft (SVG) aneurysms appears usually about 10-20 years after the operation at an estimated rate of <1%. Determining the optimal management of asymptomatic patients with SVG aneurysm still remains a challenging problem, and has been traditionally considered as an indication for cardiac surgery. A 64-year-old male patient, who underwent coronary artery bypass graft (CABG) surgery 18 years earlier, complicated with a giant saphenous vein graft aneurysm presenting with typical angina pectoris and exertional dyspnea after years of asymptomatic period. This condition was successfully treated with repeat operation, aneurysm resection, and placement of new bypass grafts.

PS 0084 Cardiology

Pheochromocytoma Presenting with Takotsubo Cardio- myopathy

Zhen-Yu LIAO1, Su-Kiat CHUA1, Kou-Gi SHYU1,3, Huey-Ming LO1,2, Jun-Jack CHENG1, Chiung-Zuan CHIU1,2

Division of Cardiology, Shin Kong Wu Ho-Su Memorial Hospital, Taiwan R.O.C1, School of Medicine, College of Medicine, Fu-Jen Catholic University, Taiwan R.O.C2, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan R.O.C3

Chest pain is one of the most frequently seen chief complaints in patients presenting to emergency departments, and is considered to be a high-risk one. The differential diagnosis for chest pain is broad, and potential causes range from the benign to the immediately life-threatening. Stress-induced Tako-tsubo cardiomyopathy is an acute cardiac syndrome, mimics ST elevation myocardial infarction, largely confi ned to post- menopausal women, frequently precipitated by a stressful event. The pathogenesis of Tako-tsubo cardiomyopathy is still unknown. Coincidence of stress cardiomyopathy, also referred to as Takotsubo cardiomyopathy, and pheochromocytoma is rare. We present a case of Takotsubo syndrome, which mimicked acute coronary syndrome and was found to be caused by pheochromocytoma.

PS 0085 Cardiology

A Case of Primary Pericardial Mesothelioma Presented with Well-Defi ned Mass Along with Massive Pericardial Effusion

Yoon Pyo LEE1, Gil Ja SHIN1, Kwan Chang KIM2, Yoo Kyung KIM3, Sanghui PARK4 Ewha Womans University Mokdong Hospital, Korea1, Ewha Womans University Mokdong Hospital, Ko- rea2, Ewha Womans University Mokdong Hospital, Korea3, Ewha Womans University Mokdong Hospital, Korea4

Background: Primary malignant pericardial mesothelioma is an extremely rare disease which originates primarily from pericardium. The disease’s symptoms are usually non- specifi c, and few misdiagnosed cases as acute constrictive pericarditis or tuberculous pericarditis were reported.

Case report: We present a case of 61-years-old male who visited our center with pro- gressive dyspnea, and found to have massive pericardial effusion. Contrast-enhanced chest CT scan showed a well-defi ned heterogeneously enhancing mass posterior to the left atrium. As defi nite diagnosis couldn’t be made even with fl uid cytology of the patient’s pericardial effusion, patient underwent for surgical biopsy, and the diagnosis of primary pericardial mesothelioma was made with the specimen from video-assisted thoracoscopic mass excision surgery. Full excision was unavailable due to poor demar- cation & high vascularity. Patient’s symptoms were relieved after the surgery, and he is under outpatient follow up. The CT fi ndings were rather distinctive, showing only well-defi ned mass without diffuse pericardial infi ltration. Considering these points, it can be deduced that primary pericardial mesothelioma may present in variable extent, infl uencing pathophysiology of the disease.

Conclusion: Primary pericardial mesothelioma is rare cardiac tumor often presents with pericardial effusion. For defi nite diagnosis, patient often require surgical biopsy.

The prognosis is poor, as still no treatment strategies were proven effective enough.

When the etiology of pericardial effusion is uncertain, it is recommended to consider the possibility of this rare malignancy.

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