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Oriental Medical Therapy for Sudden Sensorineural Hearing Loss

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(1)

서 론

(Sudden sensorineural hearing loss, SSHL)

.

, ,

30-60%

1-2)

.

남혜정

경희대학교 한의과 대학

Case Report

Oriental Medical Therapy for Sudden Sensorineural Hearing Loss

Hae-Jeong Nam

Department of Oriental Medicine, College of Oriental Medicine, Kyung Hee University

Objectives: Sudden sensorineural hearing loss (SSHL) is considered an ENT emergency. Despite being a well-recognized condition, SSHL remains one of the most controversial issues in otology. Nowadays, more and more patients have an interest in Oriental medicine for treatment of SSHL. So, to ascertain the therapeutic effect of Oriental Medicine on SSHL, nineteen cases of SSHL patients who had taken Oriental medical therapy in Kyung Hee Oriental Medical Hospital were examined and analyzed.

Methods: Nineteen patients who received over 10 times acupuncture therapy and a minimum 2 weeks of herbal medicine from Sep. 1, 2007 to Aug. 31, 2008 were examined and analyzed. The patients who were in the categories below were excluded:

- within 7 days after onset

- didn’t fulfill 10 times acupuncture therapy - failed to recheck hearing outcome after treatment - less than 30dB at mean dB from 250Hz~4000Hz.

Results: The patients consisted of 12 men and 7 women with a mean age of 45.63 years (19~76). Before treatment, 17 patients had tinnitus, 16 patients had pressure in the ear and 6 patients had dizziness, and mean dB of all patients was 66.89 dB. After treatment, 9 patients still had tinnitus, 4 patients felt pressure in the ear and 2 patents felt dizziness, and mean dB of all patients was 54.57dB. After treatment, 9 patients showed effectiveness in improving both hearing level and speech discrimination, 6 patients showed effectiveness only on speech discrimination and 4 patients showed no therapeutic effect.

Conclusion: Oriental medical therapy had some therapeutic effects on SSHL even it was started 7 days after onset of the disease.

Key Words : Sudden sensorineural hearing loss, SSHL, acupuncture, herbal medicine.

Received:11 February 2009 Revised:13 May 2009 Accepted:19 May 2009

Correspondence to:남혜정(Hae-Jeong Nam) 서울시 동대문구 회기동 1번지 경희대학교 한의과 대학

Tel:+82-2-958-9244, Fax:+82-2-958-9180, E-mail:handr90@korea.com

(2)

, , ,

3-9)

. corticosteroids

corticosteroids

10-13)

.

14)

3

15-17)

. MRI

corticosteroids

10 2

19 7

.

대상 및 방법

1. 연구 대상

2007 9 1 2008 8 31

10 2

19 .

.

7 10

250Hz~4000Hz 30dB

2. 치료방법

1)

1 2

.

2

.

, , , , ,

10

, , , , ,

10 .

. 2)

. .

6g 4g , ( ), ( ),

( ), , , , , , ,

, , , 2g, 6g, ,

4g, 2g

1 3-4

, .

.

6g, , , 4g, , ,

, , , , , , 2g,

, 6g.

.

: 2-12g, 2-6g

: ( ) 8-16g

: 8-12g, 2-4g

(3)

3. 청력 검사 및 평가 방법

.

(noise room, SA-1000, ( ) , ) (GSI 61, Grason-Stadler, Inc. USA)

1 .

10 ,

.

125, 250, 500, 1000, 2000, 4000,

8000 Hz 250, 500,

1000, 2000, 4000 Hz 10dB

.

결 과

19 12 , 7

45.63 (19~76 ) .

Patient Sex Age Possible cause Past history Job Sleep Feces Diet Exercise Life cycle P1 F 42 overwork hypothyroidism teacher well constipation good none regular

P2 M 51 over

drinking hypertension office worker bad normal good none regular

P3 M 47 stress hyperlipemia public officer bad normal good none regular

P4 M 49 stress hypertension,

hyperlipemia businessman well constipation good none irregular

P5 M 33 stress none office worker well normal good none regular

P6 M 67 food

poisoning hypertension no job well normal lose

appetite none regular

P7 M 37 stress hyperlipemia

Meniere dis. merchant bad constipation good none irregular

P8 F 56 stress chronic rhinitis no job bad normal good walking regular

P9 M 29 stress none office worker well normal good none regular

P10 M 76 overwork prostatism businessman well normal good multi

exercise regular

P11 F 40 stress sterility no job bad diarrhea bad none regular

P12 M 50 stress Rt. ear deafness merchant bad normal good none irregular

P13 M 49 stress HIVD operation taxi driver bad diarrhea good none irregular

P14 F 47 stress

fatigue none business

woman well constipation good none regular

P15 F 39 overwork none business

woman well normal good none regular

P16 F 48 stress none no job well constipation good none regualr

P17 M 53

stress over drinking

hypertension hyperlipemia

HIVD

merchant bad normal good none irregular

P18 M 35 stress none office

worker bad normal good none irregular

P19 F 19 anger

stress none student bad normal bad none irregular

Table 1.

(4)

14 , 4

. 7

10 .

1 .

. .

.

1 .

(Table 1).

32.63 (8~115 ) patient 1, 4, 11, 19 4 15

2 . Patient 3, 18

17

MRI

corticosteroids ,

, . 7

12

. 13 , 6

17

Patient

Duration of illness (days)

Side

Co-related symptoms

Examination (Inc MRI)

ENT admission

history

Corticosteroids therapy

OM* treatment

history

Mean Tinnitus Pressure dB

of ear Dizzy

P1 13 L exist exist none full-exam yes keep oral taking

keep injection no 92

P2 15 R exist exist exist full-exam yes keep oral taking yes 37

P3 17 L exist exist none full-exam no self-stop no 98

P4 11 L exist exist none full-exam yes keep oral taking yes 72

P5 20 R none none none full-exam yes finish no 92

P6 30 L none none exist full-exam yes keep oral taking no 90

P7 75 R exist exist exist full-exam yes finish yes 40

P8 30 R exist exist none full-exam yes finish yes 34

P9 35 R exist exist none full-exam yes finish yes 67

P10 17 L exist none none full-exam yes finish no 69

P11 8 L exist exist none full-exam yes self-stop no 51

P12 30 L exist exist none full-exam yes finish no 58

P13 115 L exist exist exist full-exam yes finish yes 117

P14 55 L exist exist exist full-exam yes selp-stop no 80

P15 48 L exist exist exist full-exam yes finish yes 54

P16 18 L exist exist none full-exam yes finish no 43

P17 50 R exist exist none full-exam yes finish no 51

P18 23 L exist exist none full-exam no finish no 36

P19 10 L exist exist none full-exam yes keep injection no 90

*

OM treatment history means previous oriental medicine therapy history before visit this hospital

Table 2.

(5)

. 16

, 6

. 19

66.89 dB .

2 (Table 2).

12.89 (10~20 ) . Patient 11, 19 17

2

. 8 (

6 , 2 ) 9

. 12

4 . 4

2

. 19

54.57dB 12.32

dB .

3 (Table 3).

19 250-4000Hz

10dB

9 10dB

6 .

4 . 9

74.11dB, 49.77dB

. 17.11

41.11 . 6

47.17dB, 42.67dB

Improvement Patient Duration

(days) Acu-Tx time

Remained-symptoms Mean dB

Tinnitus Pressure of ear Dizzy

Before After Before After Before After Before After

Improved both hearing

and speech discrimination

P1 13 16 + ± + ― ― ― 92 75

P3 17 18 + ― + ― ― ― 98 62

P4 11 15 + ± + ― ― ― 72 21

P5 20 12 ― ― ― ― ― ― 92 68

P9 35 17 + ± + ― ― ― 67 47

P10 17 10 + ― ― ― ― ― 69 55

P11 8 14 + ± + ― ― ― 51 27

P18 23 10 + + + ― ― ― 36 13

P19 10 10 + + + ― ― ― 90 80

Improved only speech discrimination

P2 15 15 + ± + ― + ― 37 30

P7 75 14 + + + ― + ― 40 36

P12 30 10 + + + ― ― ― 58 51

P15 48 20 + + + + + ― 54 52

P16 18 10 + ± + ― ― ― 43 37

P17 50 10 + ± + ― ― ― 51 50

Not Improved

P6 30 14 ― ― ― ― + ― 90 82

P8 30 10 + + + + ― ― 34 37

P13 115 10 + + + + + + 117 117

P14 55 10 + ― + + + + 80 97

+ : means exist, ± : means improved, ― : means absolutely removed.

Before & After : means before treatment and after treatment

Table 3.

(6)

. 39.33

46.33 . 4

80.25dB, 83.25

dB 57.50 .

54.75 .

(Table 4, Fig. 1, 2, 3).

고 찰

.

,

, ,

, , .

Fig. 1.

Number

Mean±SD Age

(year)

Duration (day)

Hearing before Tx(dB)

Hearing after Tx(dB) Improved both hearing level &

speech discrimination 9 41.11±16.02 17.11±8.29 74.11±21.00 49.77±24.40

Improved only speech discrimination 6 46.33±6.68 39.33±22.78 47.17±8.37 42.66±9.45

No improvement 4 54.75±9.03 57.50±40.10 80.25±34.56 83.25±34.00

Table 4.

(7)

. 2

2

.

19 2

.

Fig. 3.

Fig. 2.

(8)

.

2 .

7

7

3,4,7,10)

.

30-60%

18,19)

10)

.

1-2

, 156

20)

118 14

82 (69.49%)

65 58 (89.23%) 14

38 (24.35%) .

10 -2

1 -2

3

21,22)

.

France Van

12)

3 10

corticosteroids systemic therapy

corticosteroids 12 2/3

10dB corticosteroids

, 10 10

2 .

.

9 17.11±8.29

. , ,

40-60%

23)

.

.

9

2

. 9

4 1

.

. 19

.

7 . 19

4 8-14

.

250-4000Hz

10dB

12)

(9)

. 40dB

. patient 1, 3, 4, 5, 9, 10, 11, 18, 19 patient 2, 7, 12, 15, 16, 17

patient 6, 8, 13, 14

patient 4, 11, 18

patient 2, 7, 12, 16 .

.

결 론

19 9 10dB

, 6 15

7

.

.

참고문헌

1. Wilson WR, Veltri RW, Laird N, Sprinkle PM.

Viral and Epidermiologic Studies of Idiopathic Sudden Hearing Loss, Otolaryngol Head Neck Surg 1983;91(6):653-658.

2. Schuknecht HF, Donovan ED. The pathology of

idiopathic sudden sensorineural hearing loss, Arch Otorhinolaryngol, 1986;243:1-15.

3. Reisser CH, Weidauer H. Ginkgo Biloba Extract EGb 761 or Pentoxifylline for the Treatment of Sudden Deafness: A Randomized, Reference- controlled, Double-blind Study, Acta Otolaryngol 2001;121:579-584.

4. Racic G, Maslovara S, Roje Z, Dogas Z, Tafra R. Hyperbaric Oxygen in the Treatment of Sudden Hearing Loss, ORL 2003;65:317-320.

5. Suzuki H, Furukawa M, Kumagai M, Takahashi E, Matsuura K, Katori Y, et al. Defibrinogenation Therapy for Idiopathic Sudden Sensorial Hearing Loss in Comparison with High-dose Steroid Therapy, Acta Otolaryngol, 2003;123:46-50.

6. Callejo FJ, Algarra JM, Beneyto MP, Alborch MH, Ventura AM. Autoimmune Identification of Sudden Hearing Loss, Acta Otolaryngol, 2003;

123:168-171.

7. Ullrich H, Kleinjung T, Steffens T, Jacob P, Schmitz G, Strutz J. Improved Treatment of Sudden Hearing Loss by Specific Fibrinogen Aphaeresis, Journal of Clinical Apheresis 2004;

19:71-78.

8. Mentel R, Kaftan H, Wegner U, A Reibmann, L Gurtler. Are Enterovirus Infections a Co- Factor in Sudden Hearing Loss? Journal of Medical Virology 2004;72:625-629.

9. Kim MG. The Study for Combined Therapeutic Effects of Lipoprostaglandin E1 with Carbogen Inhalation on Sudden Sensorineural Hearing Loss. Korean J Otorhinolaryngol-Head Neck Surg.

2008;51:22-27.

10. Alexiou Ch, Arnold W, Fauser Cl, Schratzenstaller B, Gloddek B, Fuhrmann S, et al. Sudden Sensorineural Hearing Loss: Does Application of Glucocorticoids Make Sense? Arch Otolaryngol Head Neck Surg, 2001;127:253-258.

11. Dallan I, Bruschini L, Nacci A, Bruschini P,

Traino C, Rognini F, et al. Transtympanic Steroids

(10)

as a Salvage Therapy in Sudden Hearing Loss:

Preliminary Results, ORL, 2006;68:247-252.

12. Wijck FV, Staecker H, Lefebvre P. Topical steroid therapy using the Silverstein Microwick TM in sudden sensoineural hearing loss after failure of conventional treatment, Acta Oto-Lary- ngologica, 2007;127:1012-1017.

13. Han CS, Ahn JK, Kang MK, Park JH, Park JR, Kim HB, et al. Comparison of the Efficacy of Systemic and Intratympanic Steroid Treatment on Sudden Sensorineural Hearing Loss with Diabets.. Korean J Otorhinolaryngol-Head Neck Surg. 2008;51:227-233.

14. Park HS, Choi KD. ,

The Journal of East-West Medicines 2000;25 (2):49-62.

15. Kwon K, Choi KH, Park JY, Owi JS, Park HS, Park YH. The Clinical Study of Three Patients Hospitalized Due To Sudden Sensorineural Hearing Loss. The Journal of Oriental Medical Surgery, Ophthamology & Otolaryngology 2002;15(2):

156-168.

16. Ha MK, Choi IH. A Clinical Study of Sudden Sensorineural Hearing Loss. The Journal of Oriental Medical Surgery, Ophthamology & Oto- laryngology 2003;16(1):141-153.

17. Yoon HS, Lee SE, Han EJ, Kim YB. Six Cases of Sudden Sensorineural Hearing Loss. The Journal of Oriental Medical Ophthalmology &

Otolaryngology & Dermatology 2003;16(2):221- 243.

18. Fetterman BL, Saunders JE, Luxford WM. Prog- nosis and Treatment of Sudden Sensorineural Hearing Loss. Am J Otol 1996;17:529-536.

19. Mattox DE, Simmons FB. Natural History of Sudden Sensorineural Hearing Loss. Ann Otol Rhinol Laryngol 1977;86:463-480.

20. Lee DH, Jun BCh, Lee JH, Son DH, Yeo SW.

Clinical Analysis of Delayed Improvement in Sudden Sensorineural Hearing Loss. Korean J Otolaryngol 2006;49:695-8.

21. Yeo SW, Lee DH, Jun BC, Park SY, Park YS.

Hearing outcome of sudden sensorineural hearing loss: Long-term follow-up, Otolaryngology-Head abd Neck Surgery 2007;136:221-224.

22. Psifidis AD, Psillas GK, Daniilidis JCh. Sudden sensorineural hearing loss: Long-term follow-up results, Otolaryngology-Head abd Neck Surgery 2006;134:809-815.

23. Park HM, Jung SW, Rhee CK. Vestibular Diagnosis Indicator in Sudden Hearing Loss with Vertigo.

Acta Otolaryngol 2001; Suppl 545:80-83.

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