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Author's Reply to Case report on combining PRF with alloplastic bone substitute in Endo-Perio lesion

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I thank the readers for finding this case report interesting and raising the issue regarding the terminology used. Platelet rich plasma (PRP) was activated with calcium chloride and hence coagulated PRP term has been used here. Fibrin matrix which is achieved with the use of PRP and exogenous activators has been given different terminology in the literature like platelet rich fibrin (PRF) matrix, PRF, platelet gel, PRF clot, PRP gel [1-3]. I agree with the readers that PRF is a widely accepted term for preparation with a natural coagulation pathway earlier known as Choukron's PRF. Hence PRP/PRF gel may be a better alternative term for the preparation as in the present case report. In the past two decades, this area has gone a lot of innovations and modifications [4]. PRF is a broad term that is used for various preparations, protocols and various variables affecting its composition. As there is a lot of heterogeneity regarding the terminology used, to better compare the results and drawing an inference, these terms may be correlated with the methodology used. I am thankful for giving me the opportunity to clarify my intent in this case report.

REFERENCES

1. Yang LC, Hu SW, Yan M, Yang JJ, Tsou SH, Lin YY. Antimicrobial activity of platelet-rich plasma and other plasma preparations against periodontal pathogens. J Periodontol 2015;86:310-318.

PUBMED | CROSSREF

2. Peck MT, Hiss D, Stephen L, Satti A, Majeed A. Platelet- rich fibrin (PRF) - the effect of storage time on platelet concentration. S Afr Dent J 2015;70:448-451.

3. Isobe K, Suzuki M, Watanabe T, Kitamura Y, Suzuki T, Kawabata H, Nakamura M, Okudera T, Okudera H, Uematsu K, Nakata K, Tanaka T, Kawase T. Platelet-rich fibrin prepared from stored whole-blood samples. Int J Implant Dent 2017;3:6.

PUBMED | CROSSREF

4. Nishimoto S, Fujita K, Fujiwara T, Sotsuka Y, Tonooka M, Ishise H, Kawai K, Kakibuchi M. An attempt to make platelet rich fibrin from bone marrow aspirate. J Clin Diagn Res 2017;11:PC04-PC07.

PUBMED | CROSSREF Restor Dent Endod. 2021 Aug;46(3):e45

https://doi.org/10.5395/rde.2021.46.e45 pISSN 2234-7658·eISSN 2234-7666

Letter to the Editor

Received: Mar 20, 2021 Accepted: May 10, 2021

Goyal L

Correspondence to Lata Goyal, MDS

Ex Resident, Department of Periodontics and Community Dentistry, Dr. Ziauddin Ahmad Dental College, Aligarh Muslim University, University Road, Zakaullah Rd, Medical Colony, Aligarh, Uttar Pradesh 202002, India.

E-mail: latagoyal83@gmail.com Copyright © 2021. The Korean Academy of Conservative Dentistry

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://

creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Conflict of Interest

No potential conflict of interest relevant to this article was reported.

ORCID iDs Lata Goyal

https://orcid.org/0000-0002-0385-1316

Lata Goyal

*

Department of Periodontics and Community Dentistry, Dr. Ziauddin Ahmad Dental College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

Author's Reply to Case report on

combining PRF with alloplastic bone substitute in Endo-Perio lesion

► See the letter “Case report on combining PRF with alloplastic bone substitute in Endo-Perio lesion”

in volume 46, e44.

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