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Synthesis and Properties of 5-Aminosalicyl-L-Aspartic Acid and 5-Aminosalicyl-L-glutamic Acid as Colon-specific Prodrugs of 5-Aminosalicylic Acid

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Table  I — —  Physical  data  of  amino  acid  methyl  ester  of  5-nitrosalicylic  acid  (5-NSA)  and  amino  acid  of  5-A m ­ inosalicylic acid  (5-ASA)
Table II — Partition  coefficients  (PC)  and  retention  time  (HPLC)  of 5-ASA-amino acid conjugates

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