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124/124bp 108/122bp 110/122bp 110/110bp

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(1)

(2)

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(4)

124/124bp

108/122bp

110/122bp

110/110bp

(5)

(6)

0 0.5 1 1.5 2

0 1 2

0 5 10 15

0 1 2

0 2 4 6 8

0 1 2

0 2 4 6 8

0 1 2

No. of copy No. of copy

No. of copy No. of copy

n=109 n=63 n=9

% change in L

2

-L

4

% change in femoral neck

% change in Ward ?s triangle % change in trochanter

a,b

n=109 b n=63 n=9

n=109 n=63 n=9

n=109 n=63 n=9

a p=0.04 (ANCOVA)

0 0.5 1 1.5 2

0 1 2

0 5 10 15

0 1 2

0 2 4 6 8

0 1 2

0 2 4 6 8

0 1 2

No. of copy No. of copy

No. of copy No. of copy

n=109 n=63 n=9

% change in L

2

-L

4

% change in femoral neck

% change in Ward ?s triangle % change in trochanter

a,b

n=109 b n=63 n=9

n=109 n=63 n=9

n=109 n=63 n=9

a

p=0.04

(ANCOVA)

(7)

-40 -20 0 20 40

-80 -60 -40 -20 0

-40 -20 0 20

-80 -60 -40 -20 0 20 40

No. of copy No. of copy

0 1 2 0 1 2

No. of copy No. of copy

n=62 n=33 p=0.550

(ANOVA)

p=0.326 (ANOVA)

p=0.491 (ANOVA)

p=0.04 (ANOVA)

n=62

n=33 n=5

n=5

n=62 n=33 n=5

n=62 n=33 n=5

% change of Osteocalcin % change of Crosslaps

% change of bone alkaline phosphate % change of calcitonin

0 1 2 0 1 2

a

a -40

-20 0 20 40

-80 -60 -40 -20 0

-40 -20 0 20

-80 -60 -40 -20 0 20 40

No. of copy No. of copy

0 1 2 0 1 2

No. of copy No. of copy

n=62 n=33 p=0.550

(ANOVA)

p=0.326 (ANOVA)

p=0.491 (ANOVA)

p=0.04 (ANOVA)

n=62

n=33 n=5

n=5

n=62 n=33 n=5

n=62 n=33 n=5

% change of Osteocalcin % change of Crosslaps

% change of bone alkaline phosphate % change of calcitonin

0 1 2 0 1 2

a

a

(8)

(9)

(10)

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