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Drainage procedures for postoperative fluid collection after pancreaticoduodenectomy: A comparison of endoscopic ultrasound guided and percutaneous drainage

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AHBPSAnnals of Hepato-Biliary-Pancreatic Surgery

www.ahbps.org S96

Drainage procedures for postoperative fluid collection after pancreaticoduodenectomy:

A comparison of endoscopic ultrasound guided and percutaneous drainage

Da Hee WOO*, Jae Hoon LEE, Song Cheol KIM, Dae Wook HWANG, Ki Byung SONG, Jae Woo KWON, Ye Jong PARK

Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

BP-OP-4-2

Introduction: Postoperative fluid collection (POFC) is a common complication of pancreas resection with no clear management guidelines and high morbidity rates. This study aims to analyze clinical features of patients with POFC and compare outcomes of en- doscopic ultrasound (EUS) guided and percutaneous drainage in patients with POFC after pancreaticoduodenectomy (PD).

Methods: We analyzed demographic data, clinical data and intervention outcomes of 53 (EUS guided = 32, percutaneous = 21) pa- tients who underwent PD between January 1, 2015 and June 30, 2019 at our center.

Results: Prior to drainage, 83.0% had leukocytosis and 92.5% presented with one or more of the following signs or symptoms: fever (69.8%), abdominal pain (79.2%), and nausea/vomiting (17.0%). Fluid collection diameters showed a mean of 95 mm (range, 33 to 191 mm), of which 77.4% showed a diameter decrease of more than 50% within 8 weeks of drainage (EUS = 87.5% vs. PCD = 61.9%, p = 0.085). Eighty-two percent of sampled fluid collections showed positive culture results and post procedural IV antibiotics were used for an average of 8.1 ± 4.3 and 12.4 ± 7.4 days for EUS group (EG) and PCD group (PG) respectively (p = 0.012). EG had a shorter post-pro- cedural hospital stay than PG (9.8 ± 1.1 vs. 15.8 ± 2.2 days, p = 0.004) with no statistically significant differences in technical and clini- cal success rates, reintervention rates and adverse event rates.

Conclusions: EUS guided drainage (EUSD) and percutaneous catheter drainage (PCD) are both equally safe and effective in manag- ing POFC after PD. However, EUSD was associated with shorter IV antibiotic treatment and shorter hospital stay.

pISSN: 2508-5778ㆍeISSN: 2508-5859

Ann Hepatobiliary Pancreat Surg 2021;25 Suppl 1:S96 https://doi.org/10.14701/ahbps.BP-OP-4-2

Corresponding Author: Da Hee WOO ([email protected]) Presenter: Da Hee WOO ([email protected])

Copyright Ⓒ The Korean Association of Hepato-Biliary-Pancreatic Surgery

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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