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Letter: Factors Predicting Weight Loss after “Sleeve Gastrectomy with Loop Duodenojejunal Bypass” Surgery for Obesity (J Obes Metab Syndr 2020;29:208-14)

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https://www.jomes.org | 325 J Obes Metab Syndr 2020;29:325-326

Sleeve gastrectomy is rapidly increasing in popularity among various bariatric surgical options according to recent worldwide statistics.1 Sleeve gastrectomy has been proven effective for achiev- ing weight loss and managing obesity-related comorbidities simul- taneously.2 However, some unmet needs have been noted with this gastric-only procedure, including weight regain and the re- emergence of diabetes in the long-term.3 An increasing number of patients are expected to require intestinal bypass in addition to gastric sleeve to overcome these shortcomings, which is why in- terest in the sleeve gastrectomy with duodenojejunal bypass has been increasing recently.4,5 The article “Factors predicting weight loss after ‘sleeve gastrectomy with loop duodenojejunal bypass’

surgery for obesity” by Vennapusa et al.6 was quite informative on this topic.

However, there are critical limitations to their results and con- clusion. Although the percentage of excess weight loss (%EWL) or percentage of excess body mass index loss (%EBMIL) had been commonly used in bariatric patients, this outdated %EWL/

%EBMIL metric is largely influenced by preoperative body mass index (BMI), distorting true weight loss efficacy after bariatric surgery.7-10 The percentage of total weight loss (%TWL) metric

also generates deviation, but to a much lesser extent than %EWL/

%EBMIL, and thus is the recommended tool for reporting weight loss outcomes as the absolute change in BMI or %TWL which is less dependent on the baseline BMI.11 Again, the weight loss re- porting metric should be selected carefully when comparing the efficacy of bariatric/metabolic surgery in patients with different baseline BMI to avoid potential bias.

The authors compared several factors including age, sex, pre- operative BMI, and the presence of diabetes to identify which predict better postoperative weight loss after sleeve gastrectomy with loop duodenojejunal bypass. As expected, they demonstrat- ed that higher preoperative BMI negatively predicted %EWL, while contradictory results were shown for %TWL. This conflict- ing result led to confusion when interpreting their conclusion.

%EWL/%EBMIL should be replaced with the use of %TWL, which is the currently accepted standard weight loss reporting method to avoid confusion and controversy.

Then, the only independent factor that predicted both 1- and 3-year %TWL was the presence of diabetes. This is quite an in- teresting finding in that patients with diabetes lost significantly less weight and were more likely to regain their weight. This is in-

Copyright © 2020 Korean Society for the Study of Obesity

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Letter

Journal of Obesity & Metabolic Syndrome 2020;29:325-326 https://doi.org/10.7570/jomes20123

Letter: Factors Predicting Weight Loss after “Sleeve Gastrectomy with Loop Duodenojejunal Bypass” Surgery for Obesity (J Obes Metab Syndr

2020;29:208-14)

Ji Yeon Park*

Department of Surgery, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea

Received November 15, 2020 Reviewed December 10, 2020 Accepted December 14, 2020

* Corresponding author Ji Yeon Park

https://orcid.org/0000-0002-6178-7906 Department of Surgery, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, 807 Hoguk-ro, Buk-gu, Daegu 41404, Korea

Tel: +82-53-200-2714 Fax: +82-53-200-2027 E-mail: [email protected]

pISSN 2508-6235 eISSN 2508-7576

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Park JY Weight Loss after Sleeve Gastrectomy with Loop Duodenojejunal Bypass

J Obes Metab Syndr 2020;29:325-326

326 | https://www.jomes.org

consistent with recent study results demonstrating that the asso- ciation between the presence of diabetes and poor weight loss was most likely related to older age in patients with diabetes rath- er than diabetes itself.12 It would be informative if the authors could explore the reasons for this discrepancy by comparing the results between patients with and without diabetes. Also, if the presence of diabetes predicts poor weight loss, further analysis on weight loss difference according to the severity of diabetes could provide valuable information.

CONFLICTS OF INTEREST

The author declares no conflict of interest.

REFERENCES

1. Angrisani L, Santonicola A, Iovino P, Vitiello A, Higa K, Him- pens J, et al. IFSO worldwide survey 2016: primary, endolu- minal, and revisional procedures. Obes Surg 2018;28:3783-94.

2. Salminen P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Pero- maa-Haavisto P, et al. Effect of laparoscopic sleeve gastrecto- my vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity: the sleevepass randomized clinical trial. JAMA 2018;319:241-54.

3. Lauti M, Kularatna M, Hill AG, MacCormick AD. Weight re- gain following sleeve gastrectomy-a systematic review. Obes Surg 2016;26:1326-34.

4. Roslin M, Tugertimur B, Zarabi S, Cottam D. Is there a better design for a bariatric procedure? The case for a single anasto-

mosis duodenal switch. Obes Surg 2018;28:4077-86.

5. Huang CK, Katakwar A. Sleeve plus procedures: need of time. Surg Today 2020;50:419-22.

6. Vennapusa A, Panchangam RB, Kesara C, Chivukula T. Fac- tors predicting weight loss after “sleeve gastrectomy with loop duodenojejunal bypass” surgery for obesity. J Obes Metab Syn- dr 2020;29:208-14.

7. van de Laar A, de Caluwé L, Dillemans B. Relative outcome measures for bariatric surgery: evidence against excess weight loss and excess body mass index loss from a series of laparo- scopic Roux-en-Y gastric bypass patients. Obes Surg 2011;21:

763-7.

8. van de Laar A. Bariatric outcomes longitudinal database (BOLD) suggests excess weight loss and excess BMI loss to be inap- propriate outcome measures, demonstrating better alterna- tives. Obes Surg 2012;22:1843-7.

9. Corcelles R, Boules M, Froylich D, Hag A, Daigle CR, Amin- ian A, et al. Total weight loss as the outcome measure of choice after Roux-en-Y gastric bypass. Obes Surg 2016;26:1794-8.

10. Park JY, Kim YJ. Validation of the alterable weight loss metric in morbidly obese patients undergoing gastric bypass in Ko- rea. Obes Surg 2018;28:1704-10.

11. Brethauer SA, Kim J, el Chaar M, Papasavas P, Eisenberg D, Rogers A, et al. Standardized outcomes reporting in metabolic and bariatric surgery. Surg Obes Relat Dis 2015;11:489-506.

12. Chang WW, Hawkins DN, Brockmeyer JR, Faler BJ, Hoppe SW, Prasad BM. Factors influencing long-term weight loss af- ter bariatric surgery. Surg Obes Relat Dis 2019;15:456-61.

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