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Transient Gaze-evoked Nystagmus in Peripheral VestibulopathySun-Uk Lee

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http://neuro-ophthalmology.co.kr S107 ISSN: 2234-0971

Transient Gaze-evoked Nystagmus in Peripheral Vestibulopathy

Sun-Uk Lee

1

, Hyo-Jung Kim

2

, Jeong-Yoon Choi

1

, Ji-Soo Kim

1

1

Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam;

2

Research Administration Team, Seoul National University Bundang Hospital, Seongnam, Korea

Background and Significance: To report transient gaze-evoked nystagmus (GEN) in two patients during the recovery phase of peripheral vestibular disorders, one with acute vestibular neuritis and the other with Meniere’s disease (MD).

Case: A 52-year-old man presented spontaneous vertigo for two days. The patient showed right-beating spontaneous nystagmus, which reversed its direction into left-beating during leftward gaze and rebound nystagmus on resuming straight ahead gaze dur- ing the second day of hospitalization. Follow-up video-oculography one-month later showed no spontaneous nystagmus or GEN, but small rebound nystagmus was observed. A 61-year-old woman presented recurrent spontaneous vertigo. She had been previ- ously diagnosed MD in the left ear. Evaluation about an hour after the onset documented spontaneous nystagmus beating left- ward, downward, and counter-clockwise, and it changed its direction into right beating during rightward gaze. Follow-up video- oculography one week later showed subtle left-beating spontaneous nystagmus without direction-changing during rightward gaze.

Conclusions or Comments: GEN may occur in peripheral vestibulopathy during the recovery phase, probably due to central ad- aptation. Thus, small GEN observed during the recovery phase of unilateral peripheral vestibulopathy does not necessarily indicate a combined central lesion.

대한안신경의학회지: 제7권 Supplement 2 Clin Neuroophthalmol 7(Suppl 2):S107, Ocotober 2017

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