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A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells

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Academic year: 2021

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Figure 1 Compound K induces cell death in HCT-116 cells. (a) HCT-116 cell
Figure 2 Compound K induces autophagy in HCT-116 cells. (a) HCT-116 cells were imaged with a light microscope after 24 h of compound K treatment (20 mg/ml;
Figure 3 Compound K upregulates the expression of Atg and LC3 proteins. (a) HCT-116 cells were treated with compound K (20 mg/ml) for the indicated times
Figure 4 Compound K induces autophagy-mediated cell death via ROS generation. HCT-116 cells were treated with compound K (20 mg/ml) and/or NAC (1 mM) for 18 h.
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