The etiology of precocious puberty in boys

(1)

=

Abstract =

Clinical Experiences of Precocious Puberty due to Neoplasms in Male Infants

Young Tack Song, M.D.

Department of Surgery, Catholic University Medical College, Seoul, Korea

Precocious puberty is difficult to define because of the marked variation in the age

at which puberty begins normally, onset of puberty before 8 years

of age in girls and

9 years in boys may be considered precocious.

The etiology of precocious puberty in boys

is

usually idiopathic, but can result from adrenal and testicular tumors.

The hepatoblastoma that produces hCG is a

very rare functioning tumor known to

cause precocious puberty in boys.

Recently, author experienced one case of virilizing adrenal cortical adenoma in 22 month-old boy, one case of adrenal cortical carcinoma in 28 month-old boy, and one case of virilizing hCG-producing hepatoblastoma

in 7 year-

old boy and reviewed lit- eratures.

Index Words: Precocious puberty, Neoplasm, Male infant

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(4)

Fig. 1. This photo shows enlarged penis (7 cm in length), testicles( 4ml in volume) and scanty pubic hairs were also noted.

Fig. 3. The normal parenchyma of adrenal gland was compressed by the tumor mass. The mass had moist cut surface without encapsulation and no area of necrosis.

Fig. 2. Abdominal CT shows well-defined, low density mass in Rt. adrenal area, which was completely separat·

ed .from liver and adjacent kidney.

-88-

(5)

Fig.~. Abdominal CT shows a large. ovoid mass of heterogenous density affecting Rt. hepatic lobe.

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1. Pescovitz OH, Comite F, Hench K, et al : The NIH experience with precocious puberty

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