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Comparisons of treatment strategies for necrotizing pancreatitis

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Comparisons of Treatment Strategies for

Necrotizing Pancreatitis

by

Sun Choon Song

Major in Medicine

Department of Medical Sciences

The Graduate School, Ajou University

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Comparisons of Treatment Strategies for

Necrotizing Pancreatitis

by

Sun Choon Song

A Dissertation Submitted to The Graduate School of Ajou University

in Partial Fulfillment of the Requirements for the Degree of

Master of Medicine

Supervised by

Wook Hwan Kim, M.D., Ph.D.

Major in Medicine

Department of Medical Sciences

The Graduate School, Ajou University

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-p value 3 weeks (N=9) 〈 (N=4) Etiology 1.000 Age 0.141 Ranson's score 0.175 APACHE II 0.161 CTSI 0.593 CRP 0.227 amylase 0.384 lipase 0.521 Developed pseudocys 0.217

Developed pleural effusion 0.203

Organ complication 0.628

Percutaneous drainage 0.559

Proportion of infected necrosis

by Gram stain and culture 1.000

Mean hospital stay 0.132

Mean number of admission 0.799

ICU length of stay 0.469

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-Ranson's score APACHE II

p value between two groups

Developed pseudocyst 0.545 0.103

Developed pleural effusion 1.000 0.293

Organ complication 0.069 1.000

Percutaneous drainage 0.242 1.000

Mean hospital stay 0.788 0.542

Mean number of admission 0.739 0.559

ICU length of stay 0.778 0.002

Mortality 1.000 NSa

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-Biliary, Alcoholic (N=28) p value Pseudocyst, N (%) 12 (42.9) 4 (44.4) 1.000 Pleural effusion, N (%) 9 (32.1) 8 (88.9) 0.003 Organ complication, N (%) 0.214 Lung 1 1 Heart 0 0 Kidney 1 1 Sepsis 3 2 Percutaneous drainage, N (%) 8 (28.6) 7 (77.8) 0.009 Proportion of infected necrosis (%) 32 100 0.000 Mean hospital stay, day 34.9±27.5 50.0±22.4 0.117 Mean number of admission, N 2.5±2.2 1.1±0.3 0.080 ICU length of stay, day 2.7±5.0 15.9±14.8 0.000

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