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Biochemical Characterization of the Drosophila Wingless Signaling Pathway Based on RNA Interference

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FIG. 3. Effect of overexpression of CKI␣, CKI ε , Zw3, Daxin, and Dsh on Arm phosphorylation status
FIG. 4. Effect of RNAi-mediated downregulation of CKI␣, Zw3, and Daxin expression on Arm phosphorylation
FIG. 6. Wg/Wnt3A signaling-induced changes in Arm/␤-catenin phosphorylation in the presence or absence of lactacystin
FIG. 8. RNAi experiments to evaluate the function of PP2A-C in Wg signaling. (A) PP2A-C counteracts Arm phosphorylation at Ser56 and at Ser44 plus Ser48, as well as Daxin phosphorylation
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