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Osteoporotic Hip Fracture in the Elderly Patients: Physicians’ Views

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© 2013 The Korean Academy of Medical Sciences.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

pISSN 1011-8934 eISSN 1598-6357

Osteoporotic Hip Fracture in the Elderly Patients: Physicians’

Views

Young-Kyun Lee and Kyung-Hoi Koo

Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Korea http://dx.doi.org/10.3346/jkms.2013.28.7.976 • J Korean Med Sci 2013; 28: 976-977

EDITORIAL

Musculoskeletal Disorders

Osteoporotic hip fracture is a major healthcare problem, which is associated with a significant mortality, morbidity and socio­

economic burden in elderly patients (1). Recently, this type of fracture affects about 20,000 adults annually in Korea (2). The incidence in 2008 was 139/100,000 men, and 286/100,000 wo­

men (3). The residual lifetime risk of osteoporosis­related frac­

ture for individuals over age 50 was 23.8% in men and 59.5% in women. That risk of osteoporotic hip fracture was 5.3% in men and 12.3% in women (2,3). These rates in Korea are compatible with those in Japan; 5.6% in men and 20.0% in women (4). Un­

like other developed countries (5), the incidence of osteoporot­

ic hip fracture seems to increase in Korea (6).

Usually, the initial care of the hip fracture starts with a medi­

cal evaluation at the emergency room. Hip fractures almost al­

ways require a surgical intervention, which should be perform­

ed as early as possible, because delayed surgery is associated with excess mortality and prolonged hospitalization. However, a cautious medical evaluation and immediate clearance should be performed to reduce perioperative complications. Internal fixation and hip replacement arthroplasty are common surgical treatments. The proportion of hip replacement arthroplasty in­

creased while that of internal fixation decreased annually dur­

ing the 5 yr in Korea. The surgery usually is followed by a com­

prehensive multidisciplinary management including rehabili­

tation and/or nursing home care.

Pneumonia, urinary tract infection, and sore develop in more than 20% of patients after a hip fracture operation. To prevent these complications, the patients should ambulate as early as possible after the operation. The risk of complications increases especially in patients who have predisposing factors such as old age, malignancy, and previous history of venous thromboem­

bolism. Additionally, venous thromboembolism is a life­threat­

ening complication. In western countries, this complication is a common cause of death and medical prophylaxis is routinely recommended. However, the medication frequently causes a serious bleeding and infection. Korean patients have a low inci­

dence of symptomatic venous thromboembolism and quite a few fatal pulmonary embolism. Thus, medical thromboprophy­

laxis should be done cautiously in patients at risk. In most pa­

tients, mechanical prophylaxis using intermittent pneumatic compression can prevent venous thromboembolism (7). Delir­

ium is another frequent complication affecting 20% to 30% of elderly patients after hip fracture surgery (8), which is frequently undetected in clinical practice. The rate of non­detection rang­

es from 30% to 60%. Delirium may have serious consequences for the patient and the family members if not promptly diag­

nosed and treated. It is frequently prolonged or persistent, re­

sulting in increased morbidity and mortality. Therefore, an ear­

ly diagnosis by close monitoring and prompt treatment should be performed to reduce hospital stay and cost. Sufficient pain management is important to decrease the risk of delirium as well as to encourage early ambulation.

About 50% of senile patients, who experience a hip fracture, will have a second fracture within 3 to 5 yr. Immediate initiation of osteoporosis treatment and educational program decrease the risk of subsequent fracture. Therefore, osteoporosis treat­

ment is important even after hip fracture treatment. However, only 25% to 33% of patients are prescribed for osteoporosis treatment after the first hip fracture. Internationally, a compre­

hensive systematic approach has been suggested to prevent the secondary fracture (9, 10). Physicians should check vitamin D­25 level and dual­energy X­ray absorptiometry (DXA) if these tests were not done in the last 2 yr. If the patient has osteoporo­

sis, start the osteoporosis treatment immediately. Physicians should check and modify medications, which can make a pa­

tient more prone to falls, and discuss environmental modifica­

tions of poor lighting and trip hazards at home with patients and their family members. Although an interest on the second­

ary prevention has been increased in Korea (11), the preventive programs are not been activated well yet.

The 30­day mortality rate after hip fracture surgery is about 10%. Approximately 15% of patients die within 6 months and 20% within 1 yr, which are about 3.5 fold higher compared with those of general population (6). Moreover, the mortality rate in­

creases far much higher, if the patient already had medical co­

morbidities or has postoperative complications.

In conclusion, Korean populations are rapidly aging and os­

teoporotic hip fractures are projected to increase drastically.

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Lee Y-K, et al., et al. • Osteoporotic Hip Fracture in the Elderly Patients

http://jkms.org 977

http://dx.doi.org/10.3346/jkms.2013.28.7.976

Osteoporotic hip fracture appears as a significant public health problem with serious socioeconomic burden. Physicians should aware that a comprehensive approach reduces incidence, mor­

bidity and mortality of hip fractures.

REFERENCES

1. Borgström F, Sobocki P, Ström O, Jönsson B. The societal burden of os- teoporosis in Sweden. Bone 2007; 40: 1602-9.

2. Park C, Ha YC, Jang S, Jang S, Yoon HK, Lee YK. The incidence and re- sidual lifetime risk of osteoporosis-related fractures in Korea. J Bone Min- er Metab 2011; 29: 744-51.

3. Yoon HK, Park C, Jang S, Jang S, Lee YK, Ha YC. Incidence and mortality following hip fracture in Korea. J Korean Med Sci 2011; 26: 1087-92.

4. Hagino H, Furukawa K, Fujiwara S, Okano T, Katagiri H, Yamamoto K, Teshima R. Recent trends in the incidence and lifetime risk of hip frac- ture in Tottori, Japan. Osteoporos Int 2009; 20: 543-8.

5. Leslie WD, O’Donnell S, Lagacé C, Walsh P, Bancej C, Jean S, Siminoski K, Kaiser S, Kendler DL, Jaglal S. Population-based Canadian hip frac- ture rates with international comparisons. Osteoporos Int 2010; 21: 1317- 22.

6. Lee YK, Ha YC, Park C, Yoo JJ, Shin CS, Koo KH. Bisphosphonate use and increased incidence of subtrochanteric fracture in South Korea: re-

sults from the National Claim Registry. Osteoporos Int 2013; 24: 707-11.

7. Ji HM, Lee YK, Ha YC, Kim KC, Koo KH. Little impact of antiplatelet agents on venous thromboembolism after hip fracture surgery. J Korean Med Sci 2011; 26: 1625-9.

8. Lee KH, Ha YC, Lee YK, Kang H, Koo KH. Frequency, risk factors, and prognosis of prolonged delirium in elderly patients after hip fracture sur- gery. Clin Orthop Relat Res 2011; 469: 2612-20.

9. Eisman JA, Bogoch ER, Dell R, Harrington JT, McKinney RE Jr, McLel­

lan A, Mitchell PJ, Silverman S, Singleton R, Siris E. Making the first frac- ture the last fracture: ASBMR task force report on secondary fracture pre- vention. J Bone Miner Res 2012; 27: 2039-46.

10. Lih A, Nandapalan H, Kim M, Yap C, Lee P, Ganda K, Seibel MJ. Target- ed intervention reduces refracture rates in patients with incident non- vertebral osteoporotic fractures: a 4-year prospective controlled study.

Osteoporos Int 2011; 22: 849-58.

11. Lee YK, Ha YC, Yoon BH, Koo KH. Incidence of second hip fracture and compliant use of bisphosphonate. Osteoporos Int 2013; 24: 2099-104.

Address for Correspondence:

Kyung-Hoi Koo, MD Department of Orthopaedic Surgery, Seoul National University Bundang Hospital and Seoul National University College of Medicine, 166 Gumi-ro, Bundang-gu, Seongnam 463-707, Korea Tel: +82-31-787-7194, Fax: +82-31-787-4056 E-mail: khkoo@snu.ac.kr

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