2021년 제72차 대한내과학회 추계학술대회 423
￭S-383 ￭ Factors associated with Overactive bladder symptom score in patients
with type 2 diabetes mellitus
부산대학교병원 내분비내과1, 부산성모병원 내분비내과2
임명수
1, 김상수
1, 이창원
2, 이욱
1, 양소리
1, 김인주
1Background/Aims: Overactive bladder (OAB) is a common urologic condition, known to be more prevalent in patients with type 2 diabetes mellitus than in those without diabetes. Previous studies investigated the risk factors associated with diabetes mellitus that influence OAB. However, few researches have been conducted in Korean type 2 diabetes mellitus. Thus, the aim of this study is to analyze overactive bladder symptom score (OABSS) in Korean patients with type 2 diabetes mellitus and to find factors associated with OABSS.
Methods: This cross-sectional case-control study enrolled T2DM patients (n=260) including 129 male and 131 female patients. All participants underwent physical examinations and laboratory tests. Overactive Bladder Symptom Score (OABSS) was assessed by questionnaire, which consists of a total of 4 questions regarding daytime frequency, nocturia, urgency, and urinary incontinence. The overall score is the sum of the 4 scores, and the severity of OAB is divided into “mild”, total score of 1 to 5, and “moderate to severe”, total score of 6 to 15. We also checked chronic complication status, brachial-ankle pulse wave velocity (baPWV, VP-1000, Colin, Japan) and diabetic cardiac autonomic neuropathy (DiCAN, Medicore, Seoul, Korea). Data were expressed as mean ± standard error.
Independent t-tests or chi-square tests were used to make comparisons between groups and Pearson’s correlation coefficient was used for correlation analysis.
Results: Comparison of baseline characteristics between male and female T2DM patients is shown in Table 1. Female T2DM patient group had higher prevalence (19% vs. 8%, p=0.008) of “moderate to severe” OABSS than male T2DM patient group (Figure). OABSS had statistically significant correlation with age, height, PWVmax, microalbuminuria (Table 2). As we divide T2DM patients into two groups by gender, however, the correlation of OABSS with age, PWVmax and microalbuminuria was significant only in male T2DM patients (Table 3). In addition, duration of T2DM was also correlated with OABSS in male T2DM patients.
Conclusions: OABSS had significant correlation with duration of T2DM, PWVmax and microalbuminuria in men with T2DM, but not in women with T2DM.
