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Time Course of Functional Recovery and ECG Change in Takotsubo Cardiomyopathy

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61 https://e-jcvi.org

Takotsubo cardiomyopathy (TTC) is characterized by transient wall-motion abnormalities which are completely recovered within 1 month in usual.

1)2)

Although there have been several studies on the dynamic changes in cardiac function during the short-term period using 2D speckle tracking echocardiography (STE) and electrocardiography (ECG),

3)4)

detailed knowledge about the time course of functional recovery in the acute and subacute phases of TTC is still deficient. As we anticipate that a clear understanding of dynamic changes in the acute and subacute phases of TTC could enhance quick and precise management of TTC, it is worthy of exploring more data on the changes of echocardiography and ECG abnormality during these phases of TTC.

In this issue of the Journal of Cardiovascular Imaging, Lee et al.

5)

originally intended to investigate the time course of rapid left ventricular functional recovery in patients with TTC. They took advantage of 2D STE and ECG as a tool for the analysis, because 2D STE appears to be more sensitive for detecting subtle myocardial abnormalities

6)7)

and ECG is the simplest and the most widely available diagnostic test.

8)9)

On the contrary to their original intent, they could not show the precise time course of recovery in TTC partly because they performed only two evaluations during hospitalization even at a different time point.

Although this study has several limitations, it has advantages over other studies in that it showed time course of longitudinal strain in bull's eye map and T-wave abnormalities in ECG simultaneously in the mid-ventricular type, as well as the apical type. Also it showed the difference in ECG change according to the type of TTC.

In conclusion, Lee et al.

5)

found that left ventricular ejection fraction and global longitudinal strain recovered continuously throughout the acute and subacute phases and also negative T wave progressed during the acute phase and recovered more slowly during the subacute phase, especially in the apical type.

J Cardiovasc Imaging. 2020 Jan;28(1):61-62 https://doi.org/10.4250/jcvi.2019.0119 pISSN 2586-7210·eISSN 2586-7296

Editorial

Received: Dec 4, 2019 Accepted: Dec 5, 2019 Address for Correspondence:

Yong Hyun Park, MD, PhD

Division of Cardiology, Department of Internal Medicine, Pusan National University Yangsan Hospital, 20 Geumo-ro, Mulgeum-eup, Yangsan 50612, Korea.

E-mail: [email protected] Copyright © 2020 Korean Society of Echocardiography

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://

creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

ORCID iDs Yong Hyun Park

https://orcid.org/0000-0001-6122-214X Conflict of Interest

The authors have no financial conflicts of interest.

Yong Hyun Park , MD, PhD

Division of Cardiology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea

Time Course of Functional Recovery and ECG Change in Takotsubo

Cardiomyopathy

See the article “Time course of functional recovery in Takotsubo (stress) cardiomyopathy: serial

speckle tracking echocardiography and electrocardiography study” in volume 28 on page 50.

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REFERENCES

1. Templin C, Ghadri JR, Diekmann J, et al. Clinical features and outcomes of Takotsubo (stress) cardiomyopathy. N Engl J Med 2015;373:929-38.

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2. Heggemann F, Weiss C, Hamm K, et al. Global and regional myocardial function quantification by two- dimensional strain in Takotsubo cardiomyopathy. Eur J Echocardiogr 2009;10:760-4.

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3. Ishigaki D, Okuyama H, Yuki K, et al. Serial evaluation of left ventricular contraction and relaxation in Takotsubo cardiomyopathy by 2D speckle tracking echocardiography. J Med Ultrason (2001) 2012;39:265-9.

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4. Hung MJ, Kao YC, Chen WS, et al. Layer-specific quantification of myocardial deformation in sepsis- induced Takotsubo cardiomyopathy: Three case reports of a serial 2-dimensional speckle-tracking echocardiographic study. Medicine (Baltimore) 2016;95:e5250.

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5. Lee M. Time course of functional recovery in Takotsubo (stress) cardiomyopathy: serial speckle tracking echocardiography and electrocardiography study. J Cardiovasc Imaging 2020:28:50-60.

CROSSREF

6. Nowak R, Fijalkowska M, Gilis-Malinowska N, et al. Left ventricular function after takotsubo is not fully recovered in long-term follow-up: A speckle tracking echocardiography study. Cardiol J 2017;24:57-64.

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7. Geyer H, Caracciolo G, Abe H, et al. Assessment of myocardial mechanics using speckle tracking echocardiography: fundamentals and clinical applications. J Am Soc Echocardiogr 2010;23:351-69; quiz 453-5.

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8. Kosuge M, Ebina T, Hibi K, et al. Differences in negative T waves between takotsubo cardiomyopathy and reperfused anterior acute myocardial infarction. Circ J 2012;76:462-8.

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9. Mugnai G, Vassanelli F, Pasqualin G, et al. Dynamic changes of repolarization abnormalities in takotsubo cardiomyopathy. Acta Cardiol 2015;70:225-32.

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62 https://e-jcvi.org https://doi.org/10.4250/jcvi.2019.0119

Functional Recovery in Takotsubo Cardiomyopathy

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