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Necrosis Rate of Preoperative Transcatheter Arterial Chemoemboliztion in Hepatocellular Carcinoma: A Study in 77 Patients who Underwent Surgery

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Necrosis Rate of Preoperative Transcatheter Arterial Chemoemboliztion in Hepatocellular Carcinoma: A Study in 77 Patients who Underwent Surgery

Dong Won Ryu, M.D., Won Geun Kang, M.D., Dong Hoon Shin, M.D., Myung Hee Yoon, M.D. and Chung Han Lee, M.D.

Department of Surgery, Medical College of Kosin, Gospel Hospital and Chang Kee Ryo Memorial Liver Institute

Background/Aims: Transcatheter arterial chemoembolization (TACE) is the one of effective methods which treat hepato- cellular carcinoma (HCC) in patients who have unresectable tumors or poor liver function. The aim of this study is to eval- uate the histologic necrosis rate of hepatocellular carcinoma (HCC) treated with TACE.

Methods: From 1997 to 2001, 77 patients diagnosed as a HCC with percutaneous needle biposy underwent hepatic resection, who had been treated with properative TACE.

Complete necrosis rate of tumor was studied by histologic examination of resected specimens.

Results: A complete necrosis rate was demonstrated in 31.2% (24/77). A mean size of completely necrotized tumors was 2.8 cm, incompletely necrotized tumor size was 4.8 cm.

Lymph node metastasis of 77 hepatocellular carcinoma cases was shown in 5.2% (4/77). Of 24 cases with a complete necrotized tumor, lymph node metastasis was found in one case.

Conclusion: This study indicates the effectiveness of TACE on the destruction of HCC. However, the presence of viable residual tumors strongly argues for the necessity of surgical resection whenever it is possible. (Korean J HBP Surg 2002;6:38-41)

Key Words: Preoperative transcatheter arterial chemoemboli- zation, Necrosis rate, Hepatocellular carcinoma

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