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Formation of Hybrid Gold Nanoparticle-Mitochondria Complex조유승, 우진석

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Theories and Applications of Chem. Eng., 2021, Vol. 27, No. 1 457

화학공학의 이론과 응용 제27권 제1호 2021년

Formation of Hybrid Gold Nanoparticle-Mitochondria Complex 조유승, 우진석1, 조미라1, 강태욱†

서강대학교; 1가톨릭대학교 (twkang@sogang.ac.kr†)

Hybrid biological particle-metal nanoparticle complex shows unique combined and often synergetic physical and biochemical properties. Here, we propose the formation of hybrid gold nanoparticle-mitochondria complex via electrostatic attraction. First, we synthesize positively-charged uniform gold nanoparticles. Second, we selectively isolate mitochondria from L6 cells and combine the mitochondria with the positively-charged nanoparticles by controlling the concentration of mitochondria. The as-made gold nanoparticle-mitochondria complex is characterized by dark-field microscopy and scanning electron microscopy (SEM). Its biochemical property is also investigated. 

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