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2021년 제72차 대한내과학회 추계학술대회
￭S-242 ￭ Predictors of Long-term Mortality according to Sex
in Elderly Patients with Ischemic Cardiomyopathy
전남대학교병원 내과
정혜민, 윤현주, 김계훈, 김종윤, 이누리, 박혁진, 김형윤, 조재영, 안영근, 정명호, 조정관
Background/Aims: Ischemic heart failure (HF) is one of the most common cause of morbidity and mortality in the world-wide, but sex-specific predictors of mortality in elderly patients with ischemic cardiomyopathy (ICMP) have been poorly studied.
Methods: A total of 536 patients with ICMP over 65 years-old (77.8±7.1 years, 283 males) were followed for a mean of 5.4 years.
The development of death during clinical follow up was evaluated and predictors of mortality were compared.
Results: Death was developed in 137 patients (25.6%); 64 females (25.3%) vs. 73 males (25.8%). Low ejection fraction was only independent predictor of mortality in ICMP regardless sex. Diabetes (HR 1.811), elevated e/e’ (HR 2.479), elevated pulmonary artery systolic pressure (HR 2.833), anemia (HR 1.860), beta blocker non-use (HR 2.148) and angiotensin receptor blocker non-use (HR 2.100) were bad prognostic factors of long term mortality in female, whereas hypertension (HR 1.770), elevated Cr (HR 2.188) and statin non-use (HR 3.689) were predictors of mortality in male with ICMP independently.
Conclusions: Systolic dysfunction in both gender, diastolic dysfunction, beta blocker and angiotensin receptor blocker in female, statin in male have important role for long term mortality in elderly patients with ICMP. For improving long term survival, it may be necessary to approach sex-specifically.
