O b j e c t i v e s: The aim of this study was to evaluate the effects of exercise on the cardiovascular and musculoskeletal variables and quality of life in elderly women.
M e t h o d s: The study subjects were 22 in experimental group and 21 in the control group, all of who were aged 65 years and over. The subjects in the experimental group were under an exercise program 3 times a week for one year. To assess the effects of exercise in the study group, blood pressure, heart rate, lipid profile, bony metabolism, grip strength, flexibility, reaction time, and quality of life were measured.
R e s u l t s: Exercise showed the significant differences between experimental and control groups on the variables of the diastolic blood pressure, HDL-cholesterol, urinary deoxypyridinoline, flexibility, and quality of life. Compared to before the exercise in the study group, the urinary DPD level and quality of life were significantly improved at 3 months, and diastolic blood pressure, serum HDL-cholesterol, and flexibility were significantly improved by 1 year.
C o n c l u s i o n s: The study results underscore the efficacy of exercise and the need for regular exercise programs that are designed for older persons.
Key words : Exercise, Aged, Blood pressure, HDL-cholesterol, Deoxypyridinoline
㡂㎇⏎㧎㠦㍲ 㤊☯䝚⪲⁎⧾㧊 㕂䡞ὖἚ㢖 ⁒ἾỿἚ
⁎Ⰲἶ ㌌㦮 㰞㠦 ⹎䂮⓪ 䣾ὒ
㩫㦖ἓ
㩚⋾╖䞯ᾦ 㦮ὒ╖䞯 㦮䞯ᾦ㥷䞯ᾦ㔺
The Effect of Exercise on Cardiovascular and Musculoskeletal Variables and Quality of Life in Elderly Women
Eun-Kyung Chung
D e p a rtment of Medical Education, Chonnam National University Medical School
ABSTRACT
J Agri Med & Community Health 2007;32(1):41~51
* ᾦ㔶㩖㧦: 㩫㦖ἓ, 501-746 ὧ㭒ὧ㡃㔲 ☯ῂ 䞯1☯ 5⻞㰖, 㩚䢪: 062-220-4178 䕿㓺: 0 6 2 - 2 3 6 - 3 6 5 3 E-mail: [email protected]
⽎ ⏒ⶎ㦖 㩚⋾╖䞯ᾦ ⼧㤦 㧚㌗㡆ῂ㏢ 㡆ῂ゚ 㰖㤦( C U H R I - U - 2 0 0 3 4 0 )㠦 㦮䞮㡂 㡆ῂ♮㠞㦢.
昢 嵦
㤆Ⰲ⋮⧒ ⏎㧎 㧎ῂ⓪ ∎㭖䧞 㯳Ṗ䞮㡂 2 0 0 0
⎚㠦 㧊⹎ 6 5㎎ 㧊㌗㦮 ⏎㧎㧊 7 %⯒ ㌗䣢䞮㡂
⽎ỿ㩗㧎 ἶ⪏䢪 ㌂䣢(aging society)㠦 ☢㧛䞮 㡖ἶ, 2020⎚㠦⓪ 1 4 %⯒ ⍮㠊 ἶ⪏ ㌂䣢( a g e d s o c i e t y )⪲ 㰚㧛䞶 ộ㦒⪲ 㩚ⰳ♲┺. 㧊⩂䞲 㧎 ῂ㦮 ㏣䞲 ἶ⪏䢪 䡚㌗㦒⪲ 㧎䞲 㟒₆♮⓪ 㡂⩂ Ṗ㰖 ⏎㧎 ὖ⩾ ⶎ㩲 㭧㠦㍲ ⏎㧎㦮 Ị ṫⶎ㩲⓪ 㭧㣪䞲 ὖ㕂㦮 ╖㌗㧊 ♮ἶ 㧞┺[ 1 ] . 䔏䧞 ⏎㧎㠦㍲ ⽊㧊⓪ Ṗ㧻 䡚㩖䞲 ⼖䢪⓪ ⁒ ἾỿἚ㦮 ⼖䢪⪲ 㧊⓪ ⏎㧎㦮 㔶㼊 ₆⓻㩖䞮,
₆⓻㧻㞶㢖 ₆⓻㌗㔺 ❇㦒⪲ ⋮䌖⋮ 䢲☯㠦 㰗㩧㩗㧎 㡗䟻㦚 㭒㠊 ☛Ⱃ㩗㧎 㧒㌗㌳䢲㦚 㩖䟊䞶 ㈦Ⱒ 㞚┞⧒ ㌌㦮 㰞㠦 㥚䡧㦚 㭒ἶ 㧞㠊 Ṛὒ䞶 㑮 㠜⓪ 㭧㣪䞲 ⶎ㩲㧊┺[ 2 ] .
➆⧒㍲ ⏎㧎㦮 ㌌㦮 㰞ὒ ☛Ⱃ㎇㦚 䟻㌗㔲 䋺₆ 㥚䟊㍲ ⏎㧎㦮 㔶㼊 ₆⓻ 㥶㰖⓪ ⰺ㤆 㭧㣪䞮Ⳇ, Ịṫ㌗䌲㢖 㤊☯⓻⩻㦚 ἶ⩺䞮㡂 㤊
☯㦚 㔺㔲䞮⓪ ộ㧊 䞚㣪䞮┺[ 3 ] .
㰖⁞₢㰖 㡂⩂ 㡃䞯㩗 㡆ῂ⯒ 䐋䞮㡂 ⏎㧎 㠦㍲ 㤊☯㠦 㦮䞮㡂 㔶㼊㦮 ┺㟧䞲 㡗㡃㠦 㩫㩗㧎 䣾ὒṖ 㧞┺ἶ ⽊ἶ䞮ἶ 㧞┺. ⏎㧎㠦
㍲ 㤊☯㠦 㦮䞮㡂 㕂䡞ὖἚ ₆⓻㧊 䟻㌗♶ ㈦ 㞚┞⧒[4, 5] 䡞㧻 㰖㰞㎇ 㼊㰖㦮 ⼖䢪
❇ 㕂䡞ὖἚ 㥚䠮㧎㧦 ❇㦮 Ṳ㍶ 䣾ὒṖ 㯳ⳛ
♮㠞ἶ[6-8], 㡂⩂ Ṗ㰖 䢎⯊ⴂ 㔶ἓ㩚╂ⶒ 㰞㧊 ゚♮㠊 㧎㼊㦮 Ⳋ㡃₆⓻㦚 ṫ䢪㔲䅲 㰞⼧㦮 㥚䠮㦚 Ṧ㏢㔲䋾┺[9]. ⡦䞲 㤊☯㦖 㤆 㤎㯳 㧦㞚 㫊㭧Ṧ㦚 Ṳ㍶㔲䌊㦒⪲㖾 ⏎㧎 㦮 ㌌㦮 㰞㦚 䟻㌗㔲䌂 ㈦Ⱒ 㞚┞⧒[10], Sherman ❇[ 1 1 ]㦖 7 5㎎ 㧊㌗ ⏎㧎㠦㍲☚ 㤊☯
㦚 䞮Ⳋ 㑮ⳛ㦮 㡆㧻㠦 ☚㤖㧊 ♲┺ἶ ⽊ἶ䞮 㡖┺.
⁎⩂⋮ ㍶䟟㡆ῂ㠦㍲⓪ ⏎㧎㠦㍲ 㤊☯㦮 䣾 ὒ⯒ 㭒⪲ 㧒 䁷Ⳋ㠦 ῃ䞲♮㠊 㯳ⳛ䞮㡖ἶ,
┾₆Ṛ 㤊☯㦚 㔺㔲䞲 䤚 㤊☯ 㩚䤚㦮 䣾ὒ⯒
䘟Ṗ䞮㡂 ゚ᾦ㩗 㧻₆Ṛ㠦 Ỏ䂲 㤊☯㦮 䣾ὒ
⯒ ㍺ⳛ䞶 㑮 㠜┺⓪ ⶎ㩲㩦㧊 㧞┺. ⡦䞲 ⏎ 䢪㠦 ➆⯎ 㔶㼊₆⓻ ⼖䢪⋮ ㌂䣢 㕂Ⰲ㩗㧎 ⶎ
㩲⯒ ἀ㦚 Ṗ⓻㎇㧊 㡂㎇ ⏎㧎㧊 ⋾㎇ ⏎㧎⽊
┺ ⏨㦢㠦☚ ῂ䞮ἶ 㡂㎇ ⏎㧎Ⱒ㦚 ╖㌗㦒
⪲ 䞲 㡆ῂ☚ 㩲䞲㩗㧊㠞┺.
⽎ 㡆ῂ⓪ 㡂㎇ ⏎㧎㦚 ╖㌗㦒⪲ 1⎚Ṛ ′䂯 㩗㧎 㤊☯㦚 㔺㔲䞲 䤚 㕂䡞ὖἚ ⁒ἾỿἚ
⁎Ⰲἶ ㌌㦮 㰞㠦 ⹎䂮⓪ 㡗䟻㦚 䕢㞛䞮㡂 ⏎ 㧎 Ịṫ㯳㰚㠦 䣾ὒ㩗㧎 㞞㦚 Ⱎ⩾䞮⓪◆
₆㡂䞮ἶ㧦 䞮㡖┺.
堆旇 愕 愯憛
1. 櫶割堆旇
㩚⧒⋾☚ 㧒Ṳ ῆ㠦 㽳 1 0 3Ṳ㦮 ἓ⪲╏㧊 㧞
⓪◆, 㧊 㭧 2Ṳ㦮 ἓ⪲╏㦚 ⶊ㧧㥚⪲ ㆧ㞚 䞲 ἓ⪲╏㦖 㤊☯ 䝚⪲⁎⧾㦚 㔺㔲䞮⓪ 㔺䠮ῆ㦒
⪲, ⡦ ┺⯎ ἓ⪲╏㦖 ╖㫆ῆ㦒⪲ ㍶㩫䞮㡖┺.
2Ὁ㦮 ἓ⪲╏㠦 ❇⪳♲ 6 5㎎ 㧊㌗㦮 ⏎㧎✺
㭧 6Ṳ㤪 ⌊㠦 㕂㧻㧧㧊⋮ ␢㫎㭧㧊 㠜ἶ, 㤊☯ὒ ⽊䟟㧊 Ṗ⓻䞮Ⳇ, 㤊☯㦒⪲ Ịṫ㧊 㞛 䢪♶ ộ㧊⧒⓪ 㦮㌂㦮 㰚┾㦚 㰖 㞠㦖 ⍺ Ṗ㰖 㫆Ị㠦 ⳾⚦ 㩗䞿䞮Ⳋ㍲ ⽎ 㡆ῂ㦮 䀾㰖
⯒ 㧊䟊䞮ἶ ㍲Ⳋ ☯㦮䞲 ⏎㧎✺㦚 㾲㫛 㡆ῂ
╖㌗㦒⪲ 䞮㡖㦒Ⳇ 㔺䠮ῆ 2 2ⳛὒ ╖㫆ῆ 2 1 ⳛ㧊㠞┺.
㤊☯䝚⪲⁎⧾㦮 㩗㣿₆Ṛ㦖 2 0 0 3⎚ 4㤪䎆 2 0 0 4⎚ 3㤪₢㰖 1⎚㧊㠞┺.
2. 櫶割愯憛 1) 㤊☯䝚⪲⁎⧾
⽎ 㡆ῂ㠦 ㌂㣿䞲 㤊☯䝚⪲⁎⧾㦖 ⹎ῃ㓺䙂 䁶㦮䞯䣢[ 1 2 ]㦮 㤊☯ Ṗ㧊✲⧒㧎⯒ 㺎ἶ䞮㡖
┺. ⡦䞲 ⏎㧎㦮 㼊⩻㣪㏢⯒ Ṧ㞞䞮㡖㦒Ⳇ, 㩚 ⶎṖ㦮 㦮ἂ㦚 ✺㠊 㑮㩫 ⽊㢚䞮㡖┺.
㔺䠮ῆ㠦Ợ 㩗㣿♲ 㤊☯ 䝚⪲⁎⧾㦖 㰧┾㦒
⪲ 㔲䟟䞮㡖㦒Ⳇ, 㓺䔎⩞䃃㧊 䙂䞾♲ 㭖゚ 㤊
☯ὒ 㩫Ⰲ㤊☯㦒⪲ 㔲㧧ὒ ⰞⶊⰂ䞮㡖┺. ⽎ 㤊☯㦖 ㌗㰖㤊☯ὒ 䞮㰖㤊☯㦒⪲ ⋮③ 㑮 㧞 㦒Ⳇ, ㌗㰖㤊☯㦖 ⲎⰂ ☢Ⰲ₆, 㞴㦒⪲ 䕪 㢂Ⰲ
₆, 㡜㦒⪲ 䕪 㢂Ⰲ₆, 㟧䕪㦚 䘊㍲ 㞴㦒⪲ ⳾ 㦒⓪ ☯㧧, 㟧䕪㦚 㩧㠊㍲ 㞴㦒⪲ ⳾㦒⓪ ☯㧧,
㟧䕪㦚 䘊㍲ 㥚㠦㍲ 䞾℮ 䦪✲⓪ ☯㧧, 䕪∞䂮 ΐ䧞₆, 䕪∞䂮 䘊₆, 㥚㠦㍲ ╏₆⓪ ☯㧧, 㟧 䕪㦚 ⻢⩺ 䦪✲⓪ ☯㧧, 㠊₾ 㢂Ⰲ₆, 㠊₾ ☢ Ⰲ₆, ㏦⳿ ℔㠊㍲ 䦪✲⓪ ☯㧧, 㟧䕪 ⻢⩺ ㏦ ㅟ 䂮₆, 䕪㦚 㞞㴓㦒⪲ Ⱎ⓪ ☯㧧 ❇㧊┺. ⡦ 䞲 䞮㰖㤊☯㦖 䞲 㧦㝿 ╖䘎 㦚 䎆䂮䞮
₆, ⚦ 㧦㝿 ╖䘎 㦚 䎆䂮䞮₆, 㔂ὖ㩞
✺㠊㢂Ⰲ₆, Ṗ⧓ 㢂Ⰲ₆, 䞲㴓 ┺Ⰲ⓪ ῂ
Ⰲἶ ╖㴓 ┺Ⰲ⓪ 䘊㍲ ┻㠦 ╕⓪ ☯㧧,
┺Ⰲ ⻢⩺ ⥆ἶ ⳾㦒⓪ ☯㧧, ⶊ⯤㦚 㥚⪲ 㩧
⓪ ☯㧧, ┺Ⰲ⯒ 㞴⛺⪲ ⻢⩺ ⥆⓪ ☯㧧, ┺Ⰲ
⯒ ᾦ㹾⪲ 䋂⪲㓺䟊㍲ 㩲㧦Ⰲ⪲ ☢㞚㡺⓪ ☯ 㧧, ⶊ⯤㦚 ῂ⪎┺ 㧒㠊⋮⓪ ☯㧧, 㴒⁎⩺ 㞟
₆, ⶊ⯤㦚 㞞㴓㦒⪲ ῂⰂⳊ㍲ Ἶὒ 䠞Ⰲ
⯒ 㤖㰗㧊⓪ ☯㧧 ❇㧊┺. ╖㫆ῆ㠦⓪ 㠊⟶䞲 㫆䂮☚ Ṗ䞮㰖 㞠㞮㦒Ⳇ, 䘟㌗㔲㦮 Ṳ㧎 䢲☯
㦚 㥶㰖䞮㡖┺.
㭖゚㤊☯ 1 0, ⽎ 㤊☯ 3 0, 㩫Ⰲ㤊☯ 1 0
㽳 5 0 ☯㞞, 㭒 3䣢㝿 㑮䟟䞮☚⪳ 䞮㡖㦒Ⳇ,
⽎ 㤊☯㦖 1㭒䎆 3㭒₢㰖⓪ 1 5㠦㍲ 3 0₢
㰖 1㭒㠦 5㝿 㯳Ṗ, 4㭒䎆 3 0 ☯㞞 㔺㔲
♮㠞┺.
2) 䁷㩫☚ῂ
⽎ 㡆ῂ㠦㍲ ⏎㧎㠦㍲㦮 㤊☯ 䣾ὒ⯒ 䕢㞛 䞮₆ 㥚䟊㍲ 㕂䡞ὖἚ ὖ⩾ 㰖䚲⪲⓪ 䡞㞫ὒ 㕂☯㑮, 䡞㼃㰖㰞㎇㦚, ⁒ἾỿἚ ὖ⩾ 㰖 䚲⪲⓪ Ἶ╖㌂㰖䚲, 㞛⩻, 㥶㡆㎇, ⹒㻿㎇㦚 ⁎ Ⰲἶ ㌌㦮 㰞㠦 ╖䞲 ⶎ䟃㦚 㤊☯㦚 㔺㔲䞮₆ 㩚, 㤊☯ 㔺㔲 3Ṳ㤪 䤚, ⁎Ⰲἶ 1⎚ 䤚㦮 ṗ 㔲₆㠦 ⳾✶ 㔺䠮ῆὒ ╖㫆ῆ㦚 ╖㌗㦒⪲ 䁷 㩫䞮㡖┺.
䡞㞫 㕂㑮⓪ 㧦☯㩚㼊䡞㞫Ἒ⯒ 㧊㣿䞮 㡂 㩗㠊☚ 5 㧊㌗ 䦊㔳㦚 䀾䞲 䤚㠦 ❇㧊 㦮㧦㠦 䘎䞮Ợ 㞟㦖 㧦㎎㠦㍲ 1 Ṛỿ㦒⪲
㡺⯎㴓 ㌗㢚㠦㍲ ⚦ ⻞ 䁷㩫䞮㡖┺. 䡞㞫㦮 ἓ 㤆 2䣢㦮 䁷㩫Ṩ㧊 10 mmHg 㧊㌗ 㹾㧊Ṗ ⋮ Ⳋ 3䣢 䁷㩫䞮㡂 ⁎ 䁷㩫Ṩ✺㦮 䘟‶㦚 㔺㩲 䡞㞫䂮⪲ ㌆㩫䞮㡖┺. 12㔲Ṛ 㧊㌗ ⁞㔳 䤚 㺚 䡞 㺚Ṗ 㔺㔲♮㠞⓪◆, 䡞㼃㰖㰞㎇㦒⪲
⓪ 㽳 䆲⩞㓺䎢⪺, 㭧㎇ 㰖㰞, ⁎Ⰲἶ ἶ⹖☚
䆲⩞㓺䎢⪺㦚 䁷㩫䞮㡖ἶ, Ἶ╖㌂㰖䚲⪲⓪ 䃒 㓮, ⶊ₆㧎, 㡺㓺䎢㡺䃒㔶, ⁎Ⰲἶ DPD ( D e o x y p y r i d i n o l i n e )⯒ 䁷㩫䞮㡖┺. 㞛⩻㦖 㞛⩻
Ἒ(Grip D-TKK 5401, Japan)⯒ 㧊㣿䞮㡂 䁷㩫 䞮㡖㦒Ⳇ, 㰗Ⱃ㧦㎎⪲ ⚦㦚 㧦㡆㓺⩓Ợ ⻢Ⰶ
┺㦢 䕪㦚 㧦㡆㓺⩓Ợ ⌊Ⰲἶ 㞛⩻ἚṖ 㔶㼊
⋮ 㢍㠦 ╕㰖 㞠☚⪳ 䞮㡂 䁷㩫䞮㡖┺. 㥶㡆㎇
㦖 㩚Ὴ 㥶㡆㎇ 䁷㩫₆(Extension D-TKK 5403, Japan)⯒ 㧊㣿䞮㡖㦒Ⳇ ┻㦚 䁷㩫₆ 㦮 䕦㠦 㧊ἶ ⶊ⯤㦚 䘊ἶ 㞟㦖 䤚 㥭ⴎ 㦚 㞴㦒⪲ ῂⰂⳆ ㏦㦒⪲ ⹎⊚⩒䕦㦚 ⹖㠊
⌎ 䤚 ⹖⩺Ṛ ỆⰂ⯒ c m┾㥚⪲ 䁷㩫䞮㡖┺.
⹒㻿㎇㦖 㩚㦮 ケ㦚 ⽊ἶ 㦧䞮⓪◆ Ỏ Ⰲ⓪ 㔲Ṛ㦚 m s e c⪲ 䁷㩫䞮㡖┺. ㌌㦮 㰞㦖 Nelson ❇[ 1 3 ]㧊 Ṳ䞲 COOP Charts⯒ 㧊㣿 䞮㡂 䘟Ṗ䞮㡖┺. COOP Charts⓪ 㔶㼊㩗 ₆⓻ (physical fitness), Ṧ㩫㌗䌲(feeling), 㧒㌗䢲☯
(daily activity), ㌂䣢䢲☯(social activity), 㔶㼊 䐋㯳(pain), 㧎㰖♲ Ịṫ㌗䌲(overall health), Ị ṫ㦮 ⼖䢪(change in health), ㌂䣢㩗 㰖㰖( s o c i a l support), 㭒ὖ㩗 ㌌㦮 㰞(subjective quality of life) ❇ 9Ṳ 䟃⳿㦒⪲ ῂ㎇♮⓪◆, ⽎ 㫆㌂㠦㍲
⓪ 㰚⬢ἆὒ⯒ 㞢㞚⽊₆ 㥚䞲 䟃⳿㧎 Ịṫ㦮
⼖䢪⯒ 㩲㣎䞮ἶ 8Ṳ 䟃⳿㦚 ㌂㣿䞮Ⳇ, ṗ 䟃
⳿㠦 ╖䟊㡂 ⰺ㤆 㫡㦢 1㩦, 㫡㦢 2㩦, ⽊䐋 3 㩦, ⋮㊾ 4㩦, ⰺ㤆 ⋮㊾ 5㩦㦚 㭒㠞㦒Ⳇ 8䟃⳿
㦮 䞿㦚 ㌌㦮 㰞 㩦㑮⪲ 䞮㡖┺.
3. 把昣愯憛
㑮㰧♲ 㧦⬢⓪ SPSS for Windows 14.0㦚 㧊 㣿䞮㡂 ㍳䞮㡖┺.
㔺䠮ῆὒ ╖㫆ῆ㦮 㧒㩗 䔏㎇ ㌳䢲㔋 ὖ ⼖㑮㠦 ╖䞲 ゚ᾦ⓪ Chi-square test⯒ 㔲䟟 䞮㡖ἶ, 㤊☯㦚 㔺㔲䞮₆ 㩚㦮 㔺䠮ῆὒ ╖㫆 ῆ㦮 䁷㩫䂮㠦 ╖䞲 ゚ᾦ⓪ Student t-test⯒
㔲䟟䞮㡖┺.
㤊☯㺎㡂㠦 ➆⯎ 㕂䡞ὖἚ ⁒ἾỿἚ 㰖 䚲㢖 ㌌㦮 㰞 ⼖䢪⯒ 䢫㧎䞮ἶ㧦 㤊☯ 㔺㔲 㩚, 㤊☯ 㔺㔲 3Ṳ㤪 䤚, 㤊☯ 㔺㔲 1⎚ 䤚 䁷
㩫䞮㡂 ㍳䞮㡖㦒Ⳇ ⽋䁷㩫 ㌆㍳㦚 㔲 䟟䞮㡖┺.
冶 刂
1. 櫶割堆旇沖汞 瞿昷 1) 㧎ῂ㌂䣢䞯㩗 䔏㎇
㡆ῂ╖㌗㧦⓪ 㡆⪏⼚⪲⓪ 6 5 - 7 4㎎Ṗ 㔺䠮ῆ 㠦㍲⓪ 77.3%, ╖㫆ῆ㠦㍲⓪ 8 1 . 0 %⪲ ╖㦚 㹾㰖䞮㡖ἶ, ᾦ㥷㑮㭖⼚⪲⓪ ⶊ䞯㧊 㔺䠮ῆ㠦
㍲ 27.3%, ╖㫆ῆ㠦㍲ 3 3 . 3 %⯒ 㹾㰖䞮㡖┺. ἆ 䢒 ㌗䌲⓪ 㔺䠮ῆ㠦㍲⓪ ㌂⼚䞲 ἓ㤆Ṗ 6 3 . 6 %
⯒ 㹾㰖䞮㡖ἶ, ╖㫆ῆ㠦㍲⓪ ἆ䢒䞮㡂 ☯Ệ䞮 ἶ 㧞⓪ ἓ㤆Ṗ 6 1 . 9 %⯒ 㹾㰖䞮㡖┺.
′䂯㩗㧎 㤊☯㦖 㔺䠮ῆ㦮 4 0 . 9 %㠦㍲, ╖㫆 ῆ㦮 4 2 . 9 %㠦㍲ 䞮ἶ 㧞⓪ ộ㦒⪲ 㫆㌂♮㠞┺.
䡚㨂 䦷㡆㧦⓪ 㔺䠮ῆ㠦㍲ 13.6%, ╖㫆ῆ㠦㍲
4 . 6 %㧊㠞ἶ, 䡚㨂 㦢㭒㧦⓪ 㔺䠮ῆ㠦㍲ 1 8 . 2 % 㠦㍲ ╖㫆ῆ㠦㍲ 33.3% 㧊㠞┺.
㧒㩗 䔏㎇ ㌳䢲㔋ὖ ⼖㑮㠦㍲ 㔺䠮ῆ ὒ ╖㫆ῆ ㌂㧊㠦 㥶㦮䞲 㹾㧊Ṗ 㠜㠞┺
(Table 1).
2) 㤊☯ 㔺㔲 㩚 㕂䡞ὖἚ ⁒ἾỿἚ 㰖 䚲㢖 ㌌㦮 㰞㦮 䙂
⽎ 㡆ῂ㠦㍲ ⏎㧎㠦㍲ 㤊☯㠦 㦮䞲 㕂䡞ὖ Ἒ ⁒ἾỿἚ 㰖䚲㢖 ㌌㦮 㰞㦮 ⼖䢪⯒ 䕢 㞛䞮₆ 㥚䞮㡂 䁷㩫♲ 㰖䚲⓪ Table 2㢖 ṯ┺.
㤊☯ 㔺㔲 㩚㦮 㕂䡞ὖἚ ⁒ἾỿἚ 㰖䚲 㢖 ㌌㦮 㰞㠦㍲ 㔺䠮ῆὒ ╖㫆ῆ ㌂㧊㠦 㥶㦮 䞲 㹾㧊Ṗ 㠜㠞┺.
2. 殺壟焾櫲櫖 娶幾 柲笎分凊 愕 匂凮冯凊 滆祢歆 於汞 滎 懆筚
1) 䡞㞫 㕂☯㑮 ⼖䢪
㤊☯㺎㡂㠦 ➆⯎ 䡞㞫 㕂☯㑮 ⼖䢪⓪ Table 3ὒ ṯ┺.
㞞㩫㔲 㧊㢚₆ 䡞㞫㦮 ἓ㤆 㔺䠮ῆ㠦㍲ 㤊
☯ 㔺㔲 㩚 88.05 mmHg, 㤊☯ 㔺㔲 3Ṳ㤪 䤚 86.68 mmHg, 㤊☯ 㔺㔲 1⎚ 䤚 83.73 mmHg⪲
Ṧ㏢䞮㡖㦒Ⳇ, ╖㫆ῆὒ 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 㹾 㧊⯒ ⽊㡖┺.
㞞㩫㔲 㑮㿫₆ 䡞㞫, ⰻ㞫, 㕂☯㑮⓪ 㔺䠮 ῆὒ ╖㫆ῆṚ㠦 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 㹾㧊Ṗ 㠜㠞┺.
Table 1. General characteristics in the experimental and control groups Unit : n(%) E x p e r i m e n t a l C o n t r o l
g r o u p g r o u p p - v a l u e ( n = 2 2 ) ( n = 2 1 )
General characteristics A g e ( y r ) 6 5 - 7 4 1 7 ( 7 7 . 3 ) 1 7 ( 8 1 . 0 ) 0 . 7 6 7 75 over 5 ( 2 2 . 7 ) 4 ( 1 9 . 0 )
E d u c a t i o n Y e s 1 6 ( 7 2 . 7 ) 1 4 ( 6 6 . 7 ) 0 . 6 6 5 N o 6 ( 2 7 . 3 ) 7 ( 3 3 . 3 )
Marital status M a r r i e d 8 ( 3 6 . 4 ) 1 3 ( 6 1 . 9 ) 0 . 0 9 4 W i d o w e d 1 4 ( 6 3 . 6 ) 8 ( 3 8 . 1 )
Health habits Regular exercise Y e s 9 ( 4 0 . 9 ) 9 ( 4 2 . 9 ) 0 . 8 9 7 N o 1 3 ( 5 9 . 1 ) 1 2 ( 5 7 . 1 )
S m o k i n g Y e s 3 ( 1 3 . 6 ) 1( 4.8) 0 . 6 0 7 N o 1 9 ( 8 6 . 4 ) 2 0 ( 9 5 . 2 )
Alcohol drinking Y e s 4 ( 1 8 . 2 ) 7 ( 3 3 . 3 ) 0 . 2 5 5 N o 1 8 ( 8 1 . 8 ) 1 4 ( 6 6 . 7 )
Periodic health examY e s 1 1 ( 5 0 . 0 ) 1 4 ( 6 6 . 7 ) 0 . 2 6 8 N o 1 1 ( 5 0 . 0 ) 7 ( 3 3 . 3 )
2) 䡞㼃㰖㰞㎇⼖䢪
㤊☯㺎㡂㠦 ➆⯎ 䡞㼃㰖㰞㎇㦮 ⼖䢪⓪ Table 4㢖 ṯ┺.
ἶ⹖☚ 䆲⩞㓺䎢⪺㦮 ἓ㤆 㔺䠮ῆ㠦㍲ 㤊☯
㔺㔲 㩚 43.09 mg/dL, 㤊☯ 㔺㔲 3Ṳ㤪 䤚 47.36 mg/dL, 㤊☯ 㔺㔲 1⎚ 䤚 51.09 mg/dL⪲
Table 2. Mean values of cardiovascular and musculoskeletal variables and quality of life before exercise in the experimental and control groups
Unit : mean· S D V a r i a b l e s Experimental group Contro groupl
p - v a l u e ( n = 2 2 ) ( n = 2 1 )
Systolic BP(mmHg) 1 4 4 . 4 1· 1 2 . 4 0 1 4 9 . 1 9· 1 2 . 4 0 0 . 2 3 8 Diastolic BP(mmHg) 8 8 . 0 5· 1 0 . 6 4 9 2 . 0 5· 9 . 4 4 0 . 2 0 0 Pulse pressure(mmHg) 5 6 . 3 6· 7 . 8 4 5 7 . 1 4· 9 . 3 1 0 . 7 6 8 Heart rate(beats/min) 7 8 . 9 1· 1 1 . 5 1 8 1 . 3 3· 1 2 . 0 0 0 . 5 0 3 Total cholesterol(mg/dL) 2 1 5 . 4 1· 2 4 . 5 6 2 0 3 . 4 8· 2 7 . 7 0 0 . 1 4 2 H D L - c h o l e s t e r o l ( m g / d L ) 4 3 . 0 9· 8 . 0 2 4 0 . 6 7· 7 . 0 7 0 . 3 0 0 T r i g l y c e r i d e ( m g / d L ) 1 4 7 . 7 7· 5 1 . 8 3 1 5 8 . 9 5· 5 6 . 6 3 0 . 5 0 3 L D L - c h o l e s t e r o l ( m g / d L ) 1 2 3 . 0 6· 2 3 . 8 6 1 1 1 . 8 3· 3 4 . 7 2 0 . 2 2 1 C a l c i u m ( m g / d L ) 9 . 0 9· 0 . 3 4 9 . 2 1· 0 . 2 7 0 . 2 1 8 P h o s p h o r u s ( m g / d L ) 3 . 8 1· 0 . 3 4 3 . 8 6· 0 . 6 0 0 . 7 3 3 O s t e o c a l c i n ( n g / m L ) 1 1 . 1 4· 3 . 5 0 1 3 . 0 2· 4 . 1 1 0 . 1 1 3 Deoxypyridinoline(DPD)(mM DPD/mM creatinine) 6 . 3 7· 2 . 3 6 6 . 4 5· 2 . 6 1 0 . 9 1 6 Grip strength(kg) 9 . 5 8· 4 . 1 1 1 1 . 0 4· 4 . 4 5 0 . 2 6 8 Sitting trunk flexion(cm) 1 1 . 5 0· 6 . 2 2 9 . 0 2· 6 . 4 6 0 . 2 0 8 Reaction time(msec) 7 2 3 . 0 5· 1 3 6 . 3 7 7 2 0 . 1 9· 2 0 4 . 2 8 0 . 9 5 7 Quality of life(score) 2 0 . 2 3· 2 . 5 2 2 0 . 1 0· 3 . 9 6 0 . 8 9 8
Table 3. Comparison of blood pressure and heart rate between the experimental and control groups
Unit : mean· S D V a r i a b l e s P r e t r e a t m e n t Post-3 months Post-1 year Systolic BP(mmHg)
C o n t r o l 1 4 9 . 1 9· 1 4 . 3 0 1 4 4 . 5 7· 1 5 . 7 8 1 4 8 . 7 6· 1 4 . 2 8 E x p e r i m e n t a l 1 4 4 . 4 1· 1 2 . 4 0 1 4 2 . 5 0· 1 4 . 1 0 1 3 5 . 1 8· 1 3 . 2 0 Diastolic BP(mmHg)*
C o n t r o l 9 2 . 0 5· 9 . 4 4 9 0 . 3 8· 8 . 7 0 9 2 . 0 0· 8 . 9 3 E x p e r i m e n t a l 8 8 . 0 5· 1 0 . 6 4 8 6 . 6 8· 8 . 4 7 8 3 . 7 3· 8 . 1 8 Pulse pressure(mmHg)
C o n t r o l 5 7 . 1 4· 9 . 3 1 5 4 . 1 9· 1 2 . 8 6 5 6 . 7 6· 1 0 . 4 0 E x p e r i m e n t a l 5 6 . 3 6· 7 . 8 4 5 5 . 8 2· 1 1 . 9 2 5 1 . 4 5· 1 1 . 0 3 Heart rate(beats/min)
C o n t r o l 8 1 . 3 3· 1 2 . 0 0 7 6 . 9 5· 8 . 9 6 8 0 . 3 3· 1 0 . 5 4 E x p e r i m e n t a l 7 8 . 9 1· 1 1 . 5 1 7 9 . 4 1· 1 1 . 1 6 7 1 . 5 5· 7 . 3 0
*Significant between experimental and control groups by time
㯳Ṗ䞮㡖㦒Ⳇ, ╖㫆ῆὒ 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 㹾 㧊⯒ ⽊㡖┺.
㽳 䆲⩞㓺䎢⪺ὒ 㭧㎇㰖㰞, 㩖⹖☚ 䆲⩞㓺䎢
⪺㦮 ἓ㤆⓪ 㔺䠮ῆὒ ╖㫆ῆṚ㠦 䐋Ἒ㩗㦒⪲
㥶㦮䞲 㹾㧊Ṗ 㠜㠞┺.
3) Ἶ╖㌂㰖䚲㦮 ⼖䢪
㤊☯㺎㡂㠦 ➆⯎ Ἶ╖㌂㰖䚲㦮 ⼖䢪⓪ T a b l e 5㢖 ṯ┺.
㣪㭧 D P D⓪ 㔺䠮ῆ㠦㍲ 㤊☯㔺㔲 㩚 6 . 3 7 nM DPD/mM creatinine, 㤊☯㔺㔲 3Ṳ㤪 䤚 4.45 nM DPD/mM creatinine, 㤊☯㔺㔲 1⎚ 䤚 4.09 nM DPD/mM creatinine㦒⪲ Ṧ㏢䞮㡖㦒 Ⳇ, ╖㫆ῆὒ 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 㹾㧊⯒ ⽊㡖 Table 4. Comparison of lipid profiles between the experimental and control groups
Unit : mean· S D V a r i a b l e s P r e t r e a t m e n t P o s t - 3 m o n t h s P o s t - 1 y e a r Total Cholesterol(mg/dL)
C o n t r o l 2 0 3 . 4 1· 2 7 . 7 0 2 0 0 . 0 0· 2 5 . 8 6 2 0 4 . 5 7· 2 9 . 4 8 E x p e r i m e n t a l 2 1 5 . 4 1· 2 4 . 5 4 2 1 2 . 1 4· 2 9 . 7 8 1 9 6 . 8 6· 2 6 . 1 5 H D L - C h o l e s t e r o l ( m g / d L )*
C o n t r o l 4 0 . 6 7· 7 . 0 7 4 1 . 1 0· 6 . 6 2 4 2 . 9 5· 1 0 . 5 5 E x p e r i m e n t a l 4 3 . 0 9· 8 . 0 2 4 7 . 3 6· 8 . 4 6 5 1 . 0 9· 1 0 . 8 8 T r i g l y c e r i d e ( m g / d L )
C o n t r o l 1 5 8 . 9 5· 5 6 . 5 3 1 7 9 . 6 2· 8 2 . 4 8 1 8 7 . 3 8· 6 5 . 7 6 E x p e r i m e n t a l 1 4 7 . 7 7· 5 1 . 8 3 1 5 5 . 9 1· 5 1 . 7 3 1 4 0 . 3 6· 5 5 . 2 7 L D L - C h o l e s t e r o l ( m g / d L )
C o n t r o l 1 1 1 . 8 3· 3 4 . 7 2 9 9 . 0 3· 3 6 . 7 1 9 5 . 1 6· 3 4 . 8 0 E x p e r i m e n t a l 1 2 3 . 0 6· 2 3 . 8 6 1 1 2 . 8 0· 3 1 . 3 2 9 8 . 9 8· 2 4 . 0 0
*Significant between experimental and control groups by time
Table 5. Comparison of bone metabolism marker between the experimental and control groups
Unit : mean· S D V a r i a b l e s P r e t r e a t m e n t P o s t - 3 m o n t h s P o s t - 1 y e a r C a l c i u m ( m g / d L )
C o n t r o l 9 . 2 1· 0 . 2 7 8 . 6 3· 0 . 2 4 8 . 7 4· 0 . 3 3 E x p e r i m e n t a l 9 . 0 9· 0 . 3 4 8 . 8 5· 0 . 4 2 8 . 9 5· 0 . 3 1 P h o s p h o r u s ( m g / d L )
C o n t r o l 3 . 8 4· 0 . 5 5 3 . 7 8· 0 . 4 0 4 . 0 3· 0 . 4 3 E x p e r i m e n t a l 3 . 8 6· 0 . 3 1 3 . 7 5· 0 . 3 6 3 . 9 6· 0 . 4 4 O s t e o c a l c i n ( n g / m L )
C o n t r o l 1 3 . 0 2· 4 . 1 1 1 1 . 6 4· 4 . 4 3 9 . 7 0· 4 . 0 5 E x p e r i m e n t a l 1 1 . 1 4· 3 . 5 0 1 0 . 3 4· 3 . 6 1 8 . 2 3· 2 . 7 6 Deoxypyridinoline(mM DPD/mM creatinine)*
C o n t r o l 6 . 4 5· 2 . 6 1 6 . 0 7· 3 . 2 5 6 . 1 7· 2 . 5 9 E x p e r i m e n t a l 6 . 3 7· 2 . 3 6 4 . 4 5· 1 . 9 8 4 . 0 9· 1 . 5 7
* Significant between experimental and control groups by time
┺.
䡞㼃 䃒㓮, ⶊ₆㧎, 㡺㓺䎢㡺䃒㔶㦮 ἓ㤆⓪ 㔺䠮ῆὒ ╖㫆ῆṚ㠦 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 㹾㧊 Ṗ 㠜㠞┺.
4) 㞛⩻, 㥶㡆㎇, ⹒㻿㎇㦮 ⼖䢪
㤊☯㺎㡂㠦 ➆⯎ 㞛⩻, 㥶㡆㎇ ⁎Ⰲἶ ⹒㻿
㎇ ⼖䢪⓪ Table 6ὒ ṯ┺.
㥶㡆㎇㦮 ἓ㤆 㔺䠮ῆ㠦㍲ 㤊☯ 㔺㔲 㩚 11.50 cm, 㤊☯ 㔺㔲 3Ṳ㤪 䤚 12.78 cm, 㤊☯
㔺㔲 1⎚ 䤚 16.52 cm㦒⪲ 㯳Ṗ䞮㡖㦒Ⳇ, ╖㫆 ῆὒ 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 㹾㧊⯒ ⽊㡖┺.
㞛⩻ὒ ⹒㻿㎇㦮 ἓ㤆⓪ 㔺䠮ῆὒ ╖㫆ῆṚ 㠦 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 㹾㧊Ṗ 㠜㠞┺.
5) ㌌㦮 㰞 ⼖䢪
㤊☯㺎㡂㠦 ➆⯎ 䐋㯳㩫☚ ㌌㦮 㰞 ⼖䢪
⓪ Table 7ὒ ṯ┺.
㌌㦮 㰞㦮 ἓ㤆 㔺䠮ῆ㠦㍲ 㤊☯ 㔺㔲 㩚 2 0 . 2 3㩦, 㤊☯ 㔺㔲 3Ṳ㤪 䤚 1 7 . 5 5㩦, 㤊☯ 㔺㔲 1⎚ 䤚 1 7 . 7 2㩦㦒⪲ ╖㫆ῆὒ 䐋Ἒ㩗㦒⪲ 㥶㦮 䞲 㹾㧊⯒ ⽊㡖┺.
3. 柪竞剶櫖昢 柢儊櫖 娶幾 柲笎分凊 愕 匂 凮冯凊 滆祢歆 於汞 滎 懆筚
㔺䠮ῆὒ ╖㫆ῆṚ㠦 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 㹾 㧊⯒ ⽊㡖▮ 㕂䡞ὖἚ ⁒ἾỿἚ 㰖䚲㢖 ㌌ 㦮 㰞㦮 㔲Ṛ㠦 ➆⯎ ἆὒ⓪ Table 8ὒ ṯ┺.
㣪㭧 D P D㢖 ㌌㦮 㰞㦮 㰖䚲⓪ 㤊☯ 㔺㔲 㩚 㠦 ゚䟊 㤊☯ 㔺㔲 3Ṳ㤪 䤚㠦 䐋Ἒ㩗㦒⪲ 㥶 㦮䞮Ợ 䟻㌗♮㠞┺. Ⳋ㠦 㞞㩫㔲 㧊㢚₆ 䡞 㞫ὒ ἶ⹖☚ 䆲⩞㓺䎢⪺, ⁎Ⰲἶ 㥶㡆㎇㦮 㰖 䚲㦮 ἓ㤆⓪ 㤊☯ 㔺㔲 㩚㠦 ゚䟊 㤊☯ 㔺㔲 1⎚ 䤚㠦 䐋Ἒ㩗㦒⪲ 㥶㦮䞮Ợ 䟻㌗♮㠞┺.
Table 6. Comparison of physical fitness between the experimental and control groups Unit : mean· S D V a r i a b l e s P r e t r e a t m e n t P o s t - 3 m o n t h s P o s t - 1 y e a r Grip strength(kg)
C o n t r o l 1 1 . 0 4· 4 . 4 5 1 3 . 9 1· 4 . 3 6 1 3 . 1 7· 3 . 7 2 E x p e r i m e n t a l 9 . 5 8· 4 . 1 2 1 5 . 1 2· 5 . 2 3 1 5 . 1 7· 4 . 9 5 Sitting trunk flexion(cm)*
C o n t r o l 9 . 0 2· 6 . 4 6 9 . 8 6· 4 . 6 5 1 1 . 0 2· 4 . 9 7 E x p e r i m e n t a l 1 1 . 5 0· 6 . 2 2 1 2 . 7 8· 5 . 5 7 1 6 . 5 2· 6 . 4 9 Reaction time(msec)
C o n t r o l 7 2 0 . 1 9· 2 0 4 . 2 8 6 3 9 . 2 9· 1 4 2 . 9 3 4 5 5 . 3 3· 1 0 1 . 2 0 E x p e r i m e n t a l 7 2 3 . 0 5· 1 3 6 . 3 7 5 6 6 . 0 0· 2 2 0 . 0 4 4 4 5 . 9 5· 9 2 . 9 6
* Significant between experimental and control groups by time
Table 7. Comparison of quality of life between the experimental and control groups Unit : mean· S D V a r i a b l e s P r e t r e a t m e n t P o s t - 3 m o n t h s P o s t - 1 y e a r Quality of life(score)*
C o n t r o l 2 0 . 1 0· 3 . 9 6 1 9 . 5 2· 3 . 2 8 2 1 . 1 4· 3 . 3 7 E x p e r i m e n t a l 2 0 . 2 3· 2 . 5 3 1 7 . 5 5· 4 . 2 6 1 7 . 7 2· 3 . 7 8
* Significant between experimental and control groups by time
処 然
㤊☯㺎㡂㠦 ➆⯎ 㕂䡞ὖἚ ⁒ἾỿἚ 㰖 䚲㢖 ㌌㦮 㰞㦮 ⼖䢪⯒ ㍳䞲 ἆὒ 㞞㩫㔲 㧊㢚₆ 䡞㞫, ἶ⹖☚ 䆲⩞㓺䎢⪺, 㥶㡆㎇, 㣪㭧 DPD, ⁎Ⰲἶ ㌌㦮 㰞㧊 䟻㌗♮㠞┺. 䔏䧞 㤊
☯㔺㔲 㩚㠦 ゚䟊 㣪㭧 D P D㢖 ㌌㦮 㰞㦖 㤊
☯ 㔺㔲 3Ṳ㤪 䤚㠦, 㞞㩫㔲 㧊㢚₆ 䡞㞫ὒ ἶ
⹖☚ 䆲⩞㓺䎢⪺, ⁎Ⰲἶ 㥶㡆㎇㦖 㤊☯ 㔺㔲 1⎚ 䤚㠦 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 ἆὒṖ ⋮䌖⌂┺.
㤊☯㧊 䡞㞫㠦 ⹎䂮⓪ 䣾ὒ㠦 ╖䟊㍲
Blumenthal ❇[ 1 4 ]㦖 㠦㠊⪲゛ 㤊☯ 䤚 ⏎㧎㦮 㧊㢚₆ 䡞㞫㠦㍲ 㩫㩗㧎 ⼖䢪Ṗ ⋮䌖⌂┺ἶ
⽊ἶ䞲 Ⳋ, Stevensonὒ T o p p [ 1 5 ]⓪ ⏎㧎㠦 Ợ 㩖 ṫ☚ 㤊☯䝚⪲⁎⧾㦚 9Ṳ㤪Ṛ 㔺㔲䞲 ἆὒ 㑮㿫₆ 䡞㞫, 㧊㢚₆ 䡞㞫㠦 㥶㦮䞲 㹾㧊 Ṗ 㠜┺ἶ ⽊ἶ䞮㡖┺. 㧊⩂䞲 㡆ῂἆὒ㦮 㹾 㧊⓪ 㡆ῂ╖㌗㧦㦮 ㍶㩫, 㤊☯ 䝚⪲⁎⧾ 㔺㔲
₆Ṛ ⁎Ⰲἶ ⏎㧎㦮 䔏㎇㠦 ₆㧎䞲 ộ㦒⪲ ㌂
⬢♲┺. Fagard[16]㠦 㦮䞮Ⳋ ′䂯㩗㧎 㥶㌆㏢
㤊☯㔲 㩫㌗ 䡞㞫ῆ㠦㍲ 4/4 mmHg(㑮㿫₆/
㧊㢚₆)㦮 Ṧ㞫䣾ὒṖ ⋮䌖⌂ἶ ἶ䡞㞫ῆ㠦㍲
⓪ 11/6 mmHg㦒⪲ ▪ 䋆 Ṧ㞫䣾ὒṖ ⋮䌖⋲
┺ἶ 䞲┺. ⡦䞲 ⽎ 㡆ῂ㠦㍲ 㤊☯ 㔺㔲 㩚㠦
゚䟊 㤊☯ 㔺㔲 3Ṳ㤪 䤚㠦⓪ 㥶㦮䞲 㹾㧊Ṗ 㠜㠞㦒⋮ 㤊☯ 㔺㔲 1⎚ 䤚㠦 㧊㢚₆ 䡞㞫㧊 㥶㦮䞲 㹾㧊⯒ ⽊㡂 㤊☯ 㔺㔲 ₆Ṛ㠦 ➆⧒㍲
ἆὒṖ ╂⧒㰞 㑮 㧞㦢㦚 ⽊㡂㭒㠞㦒Ⳇ, ⏎㧎
㠦㍲⓪ white-coat effectṖ ┺⯎ 㡆⪏䂋㠦 ゚䟊 䄺㍲ 㧒㩗㧎 䡞㞫 䁷㩫㦒⪲ 㤊☯㦮 䣾ὒ⯒
䘟Ṗ䞮₆㠦⓪ 㠊⩺㤖㧊 㧞┺⓪ ⽊ἶ☚ 㧞┺
[17, 18].
⽎ 㡆ῂ㦮 ἶ⹖☚ 䆲⩞㓺䎢⪺㦮 ἆὒ⓪ 䡞 㭧 㰖┾⺇㰞 ⏣☚Ṗ 㥶㦮䞮Ợ ⼖䢪♮₆ 㥚䟊
㍲⓪ 㧻㔲Ṛ㦮 㤊☯㦚 䞚㣪䞲 ộ㦒⪲ ⽊ἶ䞮 ἶ 㧞⓪ Stucchi ❇[ 1 9 ]㦮 㡆ῂἆὒ㢖 㧒䂮䞮 㡖┺.
⽎ 㡆ῂ㠦㍲⓪ Ἶ╖㌂㰖䚲㠦 ╖䞲 䣾ὒ⯒
Ἶ䡫㎇㦚 ⋮䌖⌊⓪ 㡺㓺䎢㡺䃒㔶ὒ Ἶ䦷㑮⯒
⋮䌖⌊⓪ ㏢⼖㦮 D P D⪲ 䁷㩫䞮㡖⓪◆, 㧊 㰖 䚲✺㦖 㾲⁒ Ἶ╖㌂ 㡆ῂ㠦 Ⱔ㧊 ㌂㣿♮⓪ ╖ 䚲㩗㧎 㰖䚲㧒 ㈦ 㞚┞⧒, Ἶ⹖☚㦮 ⼖䢪Ṗ 㧞
₆ ⳝ ╂ 㩚䎆 Ⲓ㩖 ⼖䢪Ṗ ⋮䌖⋮⸖⪲ Ἶ
┺Ὃ㯳㦮 㡞ὒ 䂮⬢㦮 䁷Ⳋ㠦㍲☚ 㥶㣿䞮Ợ
㌂㣿♮ἶ 㧞┺[20]. 䔏䧞 ⏎㧎㦮 Ἶ㩞㦮 ἓ㤆 㠦 ⁎ 㥚䠮☚⓪ Ἶ㦮 㨂䦷㑮 㰖䚲Ṗ Ἶ䡫㎇
㰖䚲㠦 ゚䟊 ▪ 㭧㣪䞮┺ἶ 㞢⩺㪎 㧞㠊 ⽎ 㡆ῂ㠦㍲ ⋮䌖⋲ 㣪㭧 D P D㦮 Ṧ㏢⓪ 㞚㭒 㦮 㦮 㧞⓪ ἆὒ⧒ἶ 䞶 㑮 㧞┺.
㥶㡆㎇㦖 㔺䠮ῆ㠦㍲ ╖㫆ῆ⽊┺ 㯳Ṗ䞮㡖 ἶ, ⁎ ⼖䢪Ṗ 㤊☯ 㔺㔲 䤚㠦 㦮⹎ 㧞Ợ ⋮䌖
⌂┺. ⁎⩂⋮ 㧊[ 2 1 ]㦮 㡆ῂ㠦㍲⓪ ⏎㧎㠦㍲
㤊☯ 㔺㔲 9㭒 䤚㠦 㥶㡆㎇㧊 㯳㰚♲ ἆὒ⯒
⽊㡖⓪◆, 㧊⓪ 㤊☯㦮 ゞ☚⋮ ṫ☚㦮 㹾㧊 ➢ ⶎ㦒⪲ ㌂⬢♲┺. ⽎ 㡆ῂ㠦㍲⓪ 1㭒㧒㠦 3䣢 㤊☯㦚 㔺㔲䞲 Ⳋ 㧊[ 2 1 ]㦮 㡆ῂ㠦㍲⓪ 1㭒 Table 8. Improvement of cardiovascular and musculoskeletal variables and quality of life
according to time in experimental group
V a r i a b l e s
P o s t - 3 m o n t h s P o s t - 1 y e a r M e a n I m p r o v e m e n t M e a n I m p r o v e m e n t d i f f e r e n c e ( % ) d i f f e r e n c e ( % ) Diastolic BP(mmHg) - 1 . 3 7 - 1 . 6 - 4 . 3 2 - 4 . 9* H D L - C h o l e s t e r o l ( m g / d L ) 4 . 2 7 9 . 9 8 . 0 0 1 8 . 6* Deoxypyridinoline(mM DPD/mM creatinine) - 1 . 9 2 - 3 0 . 1* - 2 . 2 8 - 3 5 . 8* Sitting trunk flexion(cm) 1 . 2 8 1 1 . 1 5 . 0 2 4 3 . 7* Quality of life(score) - 2 . 6 8 - 1 3 . 2* - 2 . 5 1 - 1 2 . 4
* Significant change pre vs. post-treatment
㧒㠦 5䣢 㤊☯㦚 㔺㔲䞮㡖┺.
⏎㧎㠦㍲ 㤊☯㦖 㔶㼊㩗 ₆⓻㈦Ⱒ 㞚┞⧒
㌌㦮 㰞 㰖䚲㠦☚ 㩫㩗㧎 ἆὒ⯒ ⽊㡖⓪◆
㧊⓪ 㤊☯ 䝚⪲⁎⧾ 䤚 ㌌㦮 㰞㧊 㥶㦮䞮Ợ 㯳㰚♮㠞┺⓪ S t e v e n s o nὒ T o p p [ 1 5 ]㦮 㡆ῂ㢖 㧊[ 2 1 ]㦮 㡆ῂ ἆὒ㢖 㧒䂮䞮㡖┺.
⽎ 㡆ῂ⓪ ┺㦢ὒ ṯ㦖 ⳝ Ṗ㰖 㩲䞲㩦㦚 Ṗ 㰖ἶ 㧞┺. 㼁㱎, ⏎㧎㠦㍲ 㤊☯㦚 㔺㔲䞶 ➢ 㩗㩞䞲 㤊☯ ṫ☚ ㍺㩫㧊 㭧㣪䞮Ⳇ, 㧊⯒ 㥚䟊
㍲ 㾲╖ ㌆㏢ ㎃䀾⨟㧊⋮ 㾲╖ 㕂㑮⯒ ₆㭖 㦒⪲ 㤊☯ ṫ☚⯒ 㩫䟊㟒 䞮⓪ ộ㦒⪲ ♮㠊 㧞㦒⋮ ⽎ 㡆ῂ㠦㍲⓪ 㤊☯ ṫ☚⯒ 㤊☯ 㭧 䧮✶ 㩫☚⯒ 㭒ὖ㩗㦒⪲ ⋮䌖⌊⓪ 㭒ὖ㩗 㧎 㰖☚㠦 ➆⧒ 㫆㩞䞮㡖┺. ⁎⩂⋮ Tanuton ❇ [ 2 2 ]㠦 㦮䞮Ⳋ 㾲╖ ㌆㏢ ㎃䀾⨟ 䁷㩫㦮 ἓ㤆
⓪ ⁒⩻㧊 㟓䞲 ⏎㧎㠦Ợ 㩗㣿䞮⓪◆ 㠊⩺㤖 㧊 㧞ἶ, 㾲╖ 㕂㑮㦮 ἓ㤆⓪ ⰺ㤆 㡺㹾Ṗ 㕂䞮Ợ ⋶ 㑮 㧞㦒Ⳇ, 㡺䧞⩺ 㭒ὖ㩗 㧎㰖☚Ṗ 㤊☯ ṫ☚⯒ Ṗ⓶䞮⓪ 㫡㦖 㰖䚲Ṗ ♶ 㑮 㧞
┺ἶ 䞮㡖┺. ⚮㱎 㧒 㰖㡃 ἓ⪲╏㦮 㡂㧦
⏎㧎㦚 ╖㌗㦒⪲ 㡆ῂ䞮㡖㦒⸖⪲ 㧒 ⏎㧎㠦 Ợ 㧒䢪䞮₆㠦⓪ 㩲䞲㧊 㧞㦚 㑮 㧞┺. ㎡㱎, 㤊☯ 䝚⪲⁎⧾㦚 㔺㔲䞲 㔺䠮ῆὒ ⁎⩝㰖 㞠 㦖 ╖㫆ῆ㧊 㧒㩗 䔏㎇ ㌳䢲㔋ὖ㠦㍲ 㥶 㦮䞲 㹾㧊Ṗ 㠜㠞㰖Ⱒ, ⁎ 㣎㦮 㤊☯ 䝚⪲⁎⧾
㠦 㡗䟻㦚 ⹎䂶 㑮 㧞⓪ 㣪㧎✺㦚 䐋㩲䞮㰖 ⴑ䟞┺⓪ 㩲䞲㩦㧊 㧞┺.
⽎ 㡆ῂ㠦㍲ ⏎㧎㠦Ợ 㧒㩫₆Ṛ ′䂯㩗㧎 㤊☯㦚 㔺㔲䞲 䤚 㕂䡞ὖἚ ⁒ἾỿἚ 㰖䚲 㢖 ㌌㦮 㰞㠦 ⹎䂮⓪ 㡗䟻㦚 䕢㞛䞲 ἆὒ, 㧒
㩗㧎 ⏎䢪ὒ㩫㠦 㧞⓪ ╖㫆ῆ㦮 ⏎㧎✺㠦 㧞㠊㍲ 㕂䡞ὖἚ ⁒ἾỿἚ 㰖䚲㢖 ㌌㦮 㰞 䁷㩫Ṩ㧊 ╖ ⼖䢪Ṗ 㠜Ệ⋮ 㩖䞮♲ Ⳋ, 㤊☯ 䝚⪲⁎⧾㦚 㩗㣿䞲 㔺䠮ῆ㠦㍲⓪ 䟻㌗♮
⓪ 㟧㌗㦚 ⽊㡖┺. ➆⧒㍲ ⏎㧎㠦㍲ 㤊☯㦖 㔶 㼊㩗 ₆⓻㈦Ⱒ 㞚┞⧒ ㌌㦮 㰞㠦☚ 㩫㩗㧎 㡗䟻㦚 ⹎䂮⸖⪲ ⏎㧎㦮 Ịṫ㌗䌲㢖 㤊☯⓻⩻
㦚 Ṧ㞞䞮㡂 㤊☯䝚⪲⁎⧾㦚 㰖㏣㩗㦒⪲ 㔺㔲 䞮⓪ ộ㧊 䞚㣪䞮┺.
殚 檃
⽎ 㡆ῂ⓪ 㡂㎇ ⏎㧎㠦㍲ 1⎚Ṛ ′䂯㩗㧎 㤊
☯㦚 㔺㔲䞲 䤚 㕂䡞ὖἚ ⁒ἾỿἚ 㰖䚲㢖
㌌㦮 㰞㠦 ⹎䂮⓪ 㡗䟻㦚 䕢㞛䞮ἶ㧦 㩚⧒⋾
☚ 㧒Ṳ ῆ㠦 㧞⓪ 2Ὁ㦮 ἓ⪲╏㠦 ❇⪳♲ 6 5
㎎ 㧊㌗㦮 ⏎㧎✺⪲ 㔺䠮ῆ 2 2ⳛὒ ╖㫆ῆ 2 1 ⳛ㦚 ╖㌗㧦⪲ 䞮㡖┺. 㤊☯ 䝚⪲⁎⧾㦚 㔺䠮 ῆ㠦ỢⰢ 㭒 3䣢, 1⎚ ☯㞞 㩗㣿䞮㡖㦒Ⳇ, 㤊☯
㔺㔲㠦 ➆⯎ 䡞㞫, 㕂☯㑮, 䡞㼃㰖㰞㎇, Ἶ
╖㌂㰖䚲, 㞛⩻, 㥶㡆㎇, ⹒㻿㎇, ㌌㦮 㰞 㰖䚲
⼖䢪⯒ 䢫㧎䞮ἶ㧦 㤊☯㔺㔲 㩚, 㤊☯ 㔺㔲 3 Ṳ㤪 䤚, 㤊☯ 㔺㔲 1⎚ 䤚 䁷㩫䞮㡂 ㍳䞮㡖
┺.
㤊☯㺎㡂㠦 ➆⯎ 㕂䡞ὖἚ ⁒ἾỿἚ 㰖 䚲㢖 ㌌㦮 㰞 ⼖䢪⯒ 䁷㩫䞮㡂 ㍳䞲 ἆὒ 㞞㩫㔲 㧊㢚₆ 䡞㞫, ἶ⹖☚ 䆲⩞㓺䎢⪺, 㥶㡆
㎇, 㣪㭧 DPD, ⁎Ⰲἶ ㌌㦮 㰞㦮 㰖䚲Ṗ 䟻㌗
♮㠞┺. 䔏䧞 㤊☯ 㔺㔲 㩚㠦 ゚䟊 㣪㭧 D P D 㢖 ㌌㦮 㰞㦮 㰖䚲⓪ 㤊☯ 㔺㔲 3Ṳ㤪 䤚㠦, 㞞㩫㔲 㧊㢚₆ 䡞㞫ὒ ἶ⹖☚ 䆲⩞㓺䎢⪺, ⁎ Ⰲἶ 㥶㡆㎇㦮 㰖䚲㦮 ἓ㤆⓪ 㤊☯ 㔺㔲 1⎚
䤚㠦 䐋Ἒ㩗㦒⪲ 㥶㦮䞲 ἆὒṖ ⋮䌖⌂┺.
㧊㌗㦮 ἆὒ⪲ ⽒ ➢ ⏎㧎㠦㍲ 㤊☯㦖 㔶㼊 㩗 ₆⓻㈦Ⱒ 㞚┞⧒ ㌌㦮 㰞㠦☚ 㩫㩗㧎 㡗 䟻㦚 ⹎䂮⸖⪲ ⏎㧎㦮 Ịṫ㌗䌲㢖 㤊☯⓻⩻㦚 Ṧ㞞䞮㡂 㤊☯䝚⪲⁎⧾㦚 㰖㏣㩗㦒⪲ 㔺㔲䞮
⓪ ộ㧊 䞚㣪䞮┺.
焾処怾竒
1 . ₖ䣾㩫, ₖⳛ㞶, ἓ⹒. ⏎㧎㦮 Ⱒ㎇☯䐋 㥶 ⶊ㠦 ➆⯎ Ịṫ㌗䌲 㧒㌗㌳䢲㧻㞶 ゚ᾦ.
䞲ῃ⏣㽢㦮䞯䣢㰖 1 9 9 9 ; 2 4 ( 1 ) : 7 9 - 8 9 2 . Keller M, Leventhal H, Leventhal E.
Research on the health problems of aging and how people cope with them.
University of Winsconsin, 1991
3 . Ette AM, Branch LG. The Framingham disability study: ซ. Physical disability
among the aging. American Journal of Public Health 1 9 8 1 ; 7 1 ( 1 1 ) : 1 2 1 1 - 1 2 1 6 4 .Ogawa T, Spina RJ, Martin WH 3rd,
Kohrt WH, Schechtman KB, Holloszy JO, Ehsani AA. Effects of aging, sex and physical training on cardiovascular responses to exercise. C i r c u l a t i o n 1 9 9 2 ; 8 6 ( 2 ) : 4 9 4 - 5 0 3
5 . Hagberg JM, Graves JE, Limacher M, Woods DR, Leggett SH, Cononie C, Gruber JJ, Pollock ML. Cardiovascular responses of 70- to 79- yr old men and women to exercise training. Journal of Applied Physiology 1 9 8 9 ; 6 6 ( 6 ) : 2 5 8 9 - 2 5 9 4 6 . Katzel LI, Bleecker ER, Colman EG,
Rogus EM, Sorkin JD, Goldberg AP.
Effects of weight loss vs. aerobic exercise training on risk factors for coronary disease in healthy, obese, middle-aged and older men. a randomized controlled trial. J A M A 1 9 9 5 ; 2 7 4 ( 2 4 ) : 1 9 1 5 - 1 9 2 1
7 .Schwartz RS, Shuman WP, Larson V, Cain K, Fellingham GW, Beard JP, Kahn SE, Stratton JR, Cerqueira M, Abrass IB. The effects of intensive endurance exercise training on body fat distribution in young and older men.
Metabolism: clinical & experimental 1 9 9 1 ; 4 0 ( 5 ) : 5 4 5 - 5 5 1
8 .Seals DR, Allen WK, Hurley BF, Dalsky GP, Ehsani AA, Hagberg JM. Elevated high-density lipoprotein cholesterol levels in older endurance athletes. A m e r i c a n Journal of Cardiology 1 9 8 4 ; 5 4 ( 3 ) : 3 9 0 - 3 9 3 9 . Woods JA, Ceddia MA, Wolters BW,
Evans JK, Lu Q. McAuley E. Effects of 6 months of moderate aerobic exercise training on immune function in the elderly. Mechanisms of Ageing and
D e v e l o p m e n t1 9 9 9 ; 1 0 9 ( 1 ) : 1 - 1 9
1 0 .Spirduso WW, Cronin DL. Exercise dose-response effects on quality of life and independent living in older adults.
Medicine & Science in Sports &
E x e r c i s e 2 0 0 1 ; 3 3 ( 1 ) : S 5 9 8 - 6 0 8
1 1 .Sherman SE, D'Agostino RB, Cobb JL, Kannel WB. Does exercise reduce mortality rates in the elderly?
Experience from the Framingham Heart Study. American Heart Journal 1994;128(5): 965-972
1 2 .American College of Sports Medicine.
ACSM's Health/Fitness Facility Standards and Guideline-2nd ed. 1997 1 3 .Nelson E, Wasson J, Kirt J. Keller A,
Clark D, Dierich A, Stewart A, Zubkoff M. Assessment of function in routine clinical description of the COOP Chart method and preliminary findings.
Journal of Chronic Disease 1 9 8 7 ; 4 0 S ( 1 ) : 5 5 S - 6 3 S
1 4 .Blumenthal JA, Emery CF, Madden DJ, George LK, Coleman RE, Riddle MW, Mckee DC, Reasoner J, Williams RS. Cardiovascular and behavioral effects of aerobic exercise training in healthy older men and women. J o u r n a l of Gerontology 1 9 8 9 ; 4 4 ( 5 ) : M 1 4 6 - 1 5 7 1 5 .Stevenson JS, Topp R. Effect of
moderate and low intensity long-term exercise by older adult. Research in Nursing & Health 1 9 9 0 ; 1 3 ( 4 ) : 2 0 9 - 2 1 8 1 6 .Fagard RH. Exercise Characteristics and
the blood pressure response to dynamic physical training. Medical & Science in Sports & Exercise 2 0 0 1 ; 3 3 : S 4 8 4 - 4 9 2 1 7 .Aihara A, Imai Y, Sekino M, Kato J,
Ito S, Ohkubo T, Tsuji I, Satoh H, Hisamichi S, Nagai K. Discrepancy
between screening blood pressure and ambulatory blood pressure: a community-based study in Ohasama.
Hypertension Research-clinical &
e x p e r i m e n t a l1 9 9 8 ; 2 1 ( 2 ) : 1 2 7 - 1 3 6
1 8 .Mansoor GA, McCabe EJ, White WB.
Determinants of the white-coat effect in hypertensive subjects. Journal of Human H y p e r t e n s i o n 1 9 9 6 ; 1 0 ( 2 ) : 8 7 - 9 2
1 9 .Stucchi AF, Terpstra AH, Foxall TL, Nicolosi RJ, Smith SC. The effect of exercise on plasma lipids and LDL subclass metabolism in miniature swine.
Medicine & Science in Sports &
E x e r c i s e 1 9 9 9 ; 2 3 ( 5 ) : 5 5 2 - 5 6 1
2 0 .Looker AC, Bauer DC, Chesnut CH 3rd, Gunberg CM, Hochberg MC, Klee G, Keerekoper M, Watts NB, Bell NH.
Clinical use of biochemical markers of bone remodelling: current status and future direction. O s t e o p o r o s s i s I n t e r n a t i o n a l2 0 0 0 ; 1 1 ( 6 ) : 4 6 7 - 4 8 0
2 1 .㧊㑯㧦. ⏎㧎㦮 Ịṫ㯳㰚㦚 㥚䞲 㥾☯㩗 㤊☯䝚⪲⁎⧾㦮 㩗㣿䣾ὒ. ╖䞲Ṛ䢎䞯䣢㰖 2 0 0 0 ; 3 0 ( 3 ) 7 6 6 - 7 8 8
2 2 .Tanuton JE, Martin AD, Rhodes EC, Wolski LA, Donelly M, Elliot J.
Exercise for the older woman: choosing the right prescription. British Journal of Sports Medicine 1 9 9 7 ; 3 1 ( 1 ) : 5 - 1 0
