140 32nd World Congress of Internal Medicine (October 24-28, 2014) WCIM 2014
PS 0351 Epidemiology and Public Health High Infl uenza Vaccine Coverage Among Residents of a Single Nursing Home
Ewa GYRCZUK1, Aneta NITSCH-OSUCH1, Katarzyna ZYCINSKA1, Kazimierz WARDYN1 Warsaw Medical University, Poland1
Background: Infl uenza is a serious clinical and epidemiological problem. The diseases is transmitted by droplet or contact way, outbreaks of the diseases were reported among patients of nursing homes. Vaccination is the most effective preventive ac- tivity. The aim of the study was to describe the infl uenza vaccine coverage among patients of a chosen nursing home in Pruszków (Poland).
Methods: The analysis of medical documentation of 86-94 residents aged 4-70 years was conducted. The analyzed period was 2008-2012. Age distribution of residents was: patients younger than 18 years – 11%, aged 19-30 - 13%, aged 31-50 - 25%, older than 50 years - 51%. Most residents (45%) were diagnosed as severe retarded, 11% - mild retarded, 19% - moderate retarded, 25% - very severe retarded.
Results: Every year 100% of residents were vaccinated against infl uenza. The vaccine was well tolerated – no side effects were reported.
Conclusions: The infl uenza vaccine coverage rate in this particular nursing home was ideally high and should be followed by other nursing homes in Poland.
PS 0353 Epidemiology and Public Health National Survey for Assessment of Level of Behavioral Development of the General Public about Hepatitis C Virus
Ammal Mokhtar METWALLY1, Amany T ABDEL HAMEED1, Dalia M ELMOSALAMI1, Amira MOHSEN1, Sherif EL DEEB1, Walaa A FOUAD1
National Research Center of Egypt, Egypt1
Background: Scientifi c research clearly showed that personal health behaviors played a major role in endemicity of Hepatitis, mainly Hepatitis C (HCV) in Egypt. The study was a national survey that focused on identifying the level of behavioral development con- cerning different aspects of HCV and assessing the dominance of risk practices associ- ated with infection by HCV for deciding which practices can be altered and targeted.
Methods: This study was conducted through a project that was supported fi nancially by the Science and Technology Development Fund (STDF), Egypt, Grant No1774, during a period of one year started from November 2012 till November 2013. The national survey was directed to 1200 sampled families with 3780 individuals. The sample was selected from six governorates as representative to the six major subdivisions of Egypt; Urban Governorates, rural and urban Lower Egypt, urban and rural Upper Egypt and the Frontier Governorates
Results: Only one fourth of the surveyed groups irrespective to their age group and sex could identify why HCV is considered dangerous reporting that it is a cause of Liver cirrhosis and liver failure. Generally speaking, participants who personally feel at risk were those who developed positive attitudes,those who tried and adopted the recommended safe practices that can prevent HCV infection (50 %), indicating that around half of individuals could participate in behaviors that increase the spread of HCV. Awareness was high (= 75%) as regard to only using previously used syringes, sharing shaving equipment, nail cutter or through needle stick injury as responsible methods for transmission of HCV.
Conclusions: Finding of the survey will put the corner stone for the development of appropriate and culture sensitive educational and multimedia materials to limit the endemicity of HCV in Egypt
PS 0354 Epidemiology and Public Health Prevalence and Associating Factors with Atypical Femoral Fractures: An Asian Single Center Based Case-Control Study
Dam KIM1, Yoon-Kyoung SUNG2, Soo-Kyung CHO2, Minkyung HAN1, Yee-Suk KIM3 Clinical Research Center for Rheumatoid Arthritis, Korea1, Hanyang University Hospital for Rheumatic Diseases, Korea2, Hanyang University Hospital, Korea3
Background: Current evidence suggests that there is an association between bisphos- phonate use and atypical femoral fractures (AFFs). However, the extent of this risk remains unclear, especially in Asian population. In this study, we aimed to estimate the proportion of AFFs among total patients with femoral fractures and to compare the characteristics of patients with AFFs with that of patients with classic femoral fractures (CFFs).
Methods: A total of 578 female patients with low-energy femoral fractures who had been hospitalized at an Asian single university hospital were retrospectively enrolled.
Patients were classifi ed into two groups according to the site of fracture: AFF group for patients with subtrochanteric or diaphyseal femoral fractures and CFF group for patients with intertrochateric or neck fractures. We assessed the association of bis- phosphonate use and AFFs with using multivariate logistic regression analysis.
Results: Twenty-seven patients (4.7%) with AFFs and 551 patients (95.3%) with CFFs were identifi ed. Of the patients with AFFs, 11 (40.7%) had been treated with bisphos- phonates compared with 40 (7.3%) in the CFF group. With adjusting the age, body mass index, types of injury (slip or fall), and history of rheumatoid arthritis, bisphos- phonate was the only predictor for atypical fractures (OR 9.8, CI 3.7-26.4). Among the patients with using bisphosphonate when they fractured (n=44), the proportion of AFFs was nearly 21% (n=9). The proportions of AFFs among femoral fractures were increased according to the duration of bisphosphonate; 15.4% (n=6) in patients with
<5 years and 60% (n=3) in patients =5 years, respectively.
Conclusions: The proportion of AFFs was around 5% among the patients with fem- oral fractures and AFF were associated with bisphosphonate use in Asian ethnicity.
Longer duration of treatment resulted in augmented risk, though any period in bis- phosphonate use could cause atypical femur fracture.
