－S 391 －
￭ S-657 ￭
Kikuchi’s disease related to systemic lupus erythematosus
1Inje university, Busan, 2Hanyang university, Seoul, 3Catholic University of Daegu School of Medicine, Daegu, 4Ilsan paik hospital, Goyang
Minyoung Her1, Dongyook Kim1, Soo-Kyung Cho2, Sang-Cheol Bae2, Seong-Kyu Kim3, Bo Young Yoon4
Objective: Kikuchi’s disease is a benign disease characterizing by cervical lymphadenopathy, fever and leucopenia. Lymphadenopathy is one of common clinical manifestation of lupus, ranged from 30~70%.It can be generalized or regional distribution, especially in the cervical region.The aim of this study is to expand the number and the understanding of the cases of Kikuchi’s disease in SLE. Methods: We retrospectively reviewed the medical record of patient who had Kikuchi’s disease and SLE.The patients were from four tertiary medical centers (Pusan Paik hospital, Hanyang medical university, Ilsan Paik hospital, Catholic University of Daegu School of Medicine). Kikuchi’s disease was proven by pathologically. The diagnosis of SLE was based on the 1982 Revised ACR Criteria. Results: We found eight patients with Kikuchi’s disease related with SLE and analyzed the clinicopathological features of our collected cases.Table showed characteristics of eight patients with Kikuchi’s disease in SLE. Seven patients were women. Median age are 26.8 years.Lymphadenopathy was usually localized in cervical lesion.In five patients, SLE and Kikuchi’s disease evolve concomitantly, and three patient developed Kikuchi’s disease after the diagnosis of SLE. Among the eight patient, six patients developed skin lesion when they were diagnosed as Kikuchi’s disease. Skin biopsy was done at three patients (case1,2,8) and showed compatible lupus. Conclusion: We found that the patient with the Kikuchi’s disease associated SLE had variable skin manifestation whether lupus specific or not. We noticed that flare up of lupus was commonly found in the patient with simultaneously onset of both diseases.
￭ S-658 ￭
원위신세관산증이 동반된 전신홍반루푸스
경북대학교 의학전문대학원 내과학교실
*강진영, 김나리, 강종완, 김지훈, 임철현, 남언정, 강영모
Distal renal tubular acidosis (RTA) is characterized by a decreased net H+ secretion in collecting tubules, which results in the failure of urine acidification and clinical features of metabolic acidosis, hypokalemia, nephrolithiasis, and nephrocalcinosis. Acquired form of distal RTA is associated with tubulointerstitial involvement in immune-mediated disorders such as Sjögren’s syndrome, rheumatoid arthritis, systemic lupus erythematosus (SLE). There have been only a few reports in which the development of distal RTA preceded several years before overt manifestations of SLE. We presented a patient who showed clinical manifestations of distal RTA 21 years before the onset of overt manifestations of SLE.
