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Knockdown of Moesin Expression Accelerates Cellular Senescence of Human Dermal Microvascular Endothelial Cells

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Fig. 1. Confirming the infection of HDMEC by shRNA-lentivirus. Control vector-treated HDMECs and shRNA-lentivirus-treated HDMECs showed RFP expression at p6, p10, and p20
Fig. 3. Doubling time and doubling level of cumulative cell population. (A) The doubling time of Moesin-V group was longer than those of CTR-V group at passage 6 to 22.
Fig. 4. Expression of moesin/p16 RNA and protein. (A) Moesin RNA expression in Moesin-V group and CTR-Aged group was lower than that in CTR-V group
Fig. 6. Immunohistochemical staining of moesin and p16. (A) Immunohistoche- Immunohistoche-mical staining of moesin and p16 was performed on the neonatal prepuce (Age 1) and the skin of the 10-year-old child (Age 10) and the 86-year-old adult (Age 86)

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