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To compare head-up tilt test outcomes and hemodynamic responses in the elderly with ones in younger patients who were suspected of vasovagal syncope

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To compare head-up tilt test outcomes and hemodynamic responses in the elderly with ones in younger patients who were suspected of vasovagal syncope

Division of Cardiology, Department of Internal Medicine, Dongsan Medical Center, Keimyung University

*Han-Jun Bae, Hong-Won Shin, Ho-myoung Lee, Hyun-Ok Cho, Ji-Hyun Son, Yun-Kyeong Cho, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyung-seop Kim, Chang-Wook Nam, Seung-Ho Hur, Yun-Nyun Kim, Kwon-Bae Kim

Background: Few data are available concerning head up tilt table test (HUT) outcomes in unselected populations in the elderly. The aim of this study was to compare the elderly with younger patients in a large number of consecutive patients with unexplained syncope who underwent nitrate-potentiated head up tilt test. Methods: Consecutive outpatients with history of recurrent unexplained syncope underwent HUT by being tilted to 60 degree after supine position for five minuntes. The test was potentiated by the administration of isosorbid dinitrate spray 20 minutes after that.

The frequency of syncope occurrence and hemodynamic responses during the passive and nitrate phases of HUT were evaluated; symptoms preceding HUT-induced syncope were recorded with heart rate and arterial blood pressure values. Results: 311 (46.9%) of 633 patients were positive. The positive results showed 39.5% in those aged ≥60 years (n=215), 45.2% in the age of 36–64 years (n=272) and 58.5% in the age of ≤35years (n=176). The patients experienced HUT positive results almost after using isosorbid dinitrate spray(95.1%), and average time to syncope was 33 minutes after HUT started. HUT positive patients had increased pulse rate more than older age groups. Conclusion: The rate of nitrate-induced syncope was more frequent in younger patients. In younger patient with HUT positive, heart rate was more increased in the passive and the active phases than the one in older patients.

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