CONCLUSION

Semi-quantitative assessment of glioma vascularity using non-contrast-enhanced high-field HR-SWI shows significant correlation with the values of MR perfusion parameters, currently the best imaging modality for glioma grading. Moreover, the specificity and PPV of HR-SWI are higher than those of DSC MR perfusion because the ITSSs are rarely seen in low grade glioma. Therefore, the ITSSs are potentially helpful sign suggesting a correct diagnosis of high grade glioma. Our results show the possibility of a non-contrast brain tumor imaging protocol in patients who have contraindications for contrast agents or who cannot tolerate the bolus injection.

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-국문요약-

- 28 - 가치까지 알아보았다.

ITSSs 빈도와 rCBVmax 가 유의미한 선형 상관관계를 보였고 ITSSs 의 빈도는 세 개의 집단에서 모두 유의미한 차이를 보였다. ITSSs 의 빈도와 신경 교종의 등급 사이의 Spearman 상관계수는 0.88 이었다. ROC curve 분석을 통하 여 ITSSs 의 등급으로 신경교종의 병리학적 고 등급을 진단하는 데 있어서 민 감도, 특이도, 양성예측도, 그리고 음성예측도는 각각 85.2%, 92.9%, 95.8%, 그리 고 76.5% 였다.

결론적으로 비조영증강 고자장 고해상도 자화율 민감 영상을 사용한 신 경교종 혈관분포의 반정량적 평가는 rCBVmax 와 유의미한 상관관계가 있었고 신경교종을 등급화하는 특이도와 양성예측도는 rCBVmax 를 사용한 자기공명 관류 영상보다 더 높았다..

핵심어: 자화율 민감 영상, 신경교종, 혈관분포, 자기공명 관류 강조 영상