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Preterm Labor and Birth: Definition, Assessment, and Management

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Korean J Women Health Nurs(여성건강간호학회지) Vol. 24 No. 3, 231-232, September 2018

pISSN 2287-1640 | eISSN 2093-7695 https://doi.org/10.4069/kjwhn.2018.24.3.231

CURRENT ISSUES Open Access

Preterm Labor and Birth: Definition, Assessment, and Management

Kim, Jeung-Im

Professor, School of Nursing, Soonchunhyang University, Cheonan, Korea

Key Words: Obstetric labor, Premature; Pregnancy, High-risk; Incidence; Reproductive history; Cervical length measurement Corresponding author: Kim, Jeung-Im

School of Nursing, Soonchunhyang University, 31 Soonchunhyang 6-gil, Dongnam-gu, Chonan 31151, Korea.

Tel: +82-41-570-2493, Fax: +82-41-570-2498, E-mail: [email protected], [email protected] Received: Sep 1, 2018 / Accepted: Sep 7, 2018

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/

by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Incidences of preterm labor and preterm birth have been increasing and becoming global issues. Preterm labor is defined as regular contractions of the uterus starting be- fore 37 weeks of pregnancy that result in changes in the cervix, including effacement and dilation. Preterm birth occurs between 20 to 37 weeks of pregnancy [1].

Why do we have a concern about preterm birth? Be- cause preterm babies may be born with serious health problems. Some health problems such as cerebral palsy can last a lifetime. Other problems such as learning dis- abilities may appear later in childhood or even in adult- hood [2].

There are some well-known causes of preterm labor and preterm birth: 1) Inflammation and/or infection in the fe- toplacental unit [2]; 2) Cervical length of at least 25 mm [3];

3) High fetal fibronectin level (0.050-microgram/mL cut- off, a lower cut-point of 20 ng/mL). If we assess cervical length measurement combined with fetal fibronectin test- ing in case of a cervical length between 15 and 30 mm, we can improve the identification of women with low risk to deliver spontaneously within 7 days [4].

On the other hand, recent study reported that predictors of preterm labor symptoms in second trimester of preg- nancy were smoking experience, pregnancy complications, and pregnancy specific stress. These accounted for 19.2%

of the total variation. Predictors of preterm birth were twins, shorter cervix (<25 mm), BMI (>25 kg/m2), and a previous preterm birth. In this report, we will discuss dif- ferent points between preterm labor symptoms and pre- term birth to provide supportive care toward prevention [5].

Lastly, we will discuss management for preterm labor

to prevent preterm birth. What is the decision point? If there is a chance the baby will receive benefit from a delay in delivery, certain medications may be given. These med- ications include corticosteroids, magnesium sulfate, and tocolytics. Nursing professors should provide students in- formation about effects of those medications for their ma- ternal practicum by ACOG [1].

- Corticosteroids such as dexamethasone and bethame- thazone are drugs that can cross the placenta and help speed up the development of the baby’s lungs, brain, and digestive organs. Corticosteroids are most likely to help baby when they are given between 24~34 weeks of pregnancy.

- Magnesium sulfate is a medication that may give to women less than 32 weeks pregnant in preterm labor and those who are at risk of delivery within the next 24 hours. This medication may help reduce the risk of ce- rebral palsy that is associated with early preterm birth.

- Tocolytics are drugs used to delay delivery for a short time (up to 48 hours). They may allow time for cortico- steroids or magnesium sulfate for women to transfer to a hospital that offers specialized care for preterm infants. For protection against cerebral palsy, magne- sium sulfate also can be used as a tocolytic drug.

A cut-off value of cervical length of 25 mm has been used by clinicians and researchers to screen for women at the highest risk of spontaneous preterm birth. Recently, this group of women has been targeted with interventions to reduce the risk of spontaneous preterm birth including vaginal progesterone, cerclage, and cervical pessary. In ad- dition, current practice guidelines recommend initiation of therapy in high-risk patients with a cervical length of < 25

2018 Korean Society of Women Health Nursing http://www.women-health-nursing.or.kr

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Korean Journal of Women Health Nursing

K im , Jeung-Im

mm in the mid-trimester. However, risks for women with a previous spontaneous preterm birth with a normal cervix in pregnancy should not be neglected [6].

In conclusion, preterm birth is one of the most common obstetrical complications in humans. After many studies, it appears that its risk factors, causes, and treatments are diverse. We need to know preterm labor symptom so that we have competency in its assessment and management.

ORCID

Kim, Jeung-Im https://orcid.org/0000-0001-5499-8281

REFERENCES

1. American College of Obstetricians and Gynecologists. Preterm (premature) labor and birth[Internet]. Washington, DC: Ame- rican College of Obstetricians and Gynecologists; 2016 [cited 2018 August 13]. Available from:

https://www.acog.org/Patients/FAQs/Preterm-Premature- Labor-and-Birth

2. Gilman-Sachs A, Dambaeva S, Salazar Garcia MD, Hussein Y,

Kwak-Kim J, Beaman K. Inflammation induced preterm labor and birth. Journal of Reproductive Immunology. 2018;129:53- 58. https://doi.org/10.1016/j.jri.2018.06.029

3. Predictive value of cervical length measurement and fibronecti n testing in threatened preterm labor. Obstetrical Gynecology.

2014;123(6):1185-1192.

https://doi.org/10.1097/AOG.0000000000000229

4. Levine LD, Downes KL, Romero JA, Pappas H, Elovitz MA.

Quantitative fetal fibronectin and cervical length in sympto- matic women: results from a prospective blinded cohort study.

Journal of Maternal, Fetal, Neonatal Medicine. 2018;15:1-9.

https://doi.org/10.1080/14767058.2018.1472227

5. Kim JI, Cho MO, Choi GY. Multiple factors in the second trime ster of pregnancy on preterm labor symptoms and preterm bir th. Journal of Korean Academy Nursing. 2017;47(3):357.

https://doi.org/10.4040/jkan.2017.47.3.357-366.

6. Benoist G1. Prediction of preterm delivery in symptomatic women (preterm labor). J Gynecol Obstet Biol Reprod (Paris).

2016;45(10):1346-1363.

https://doi.org/10.1016/j.jgyn.2016.09.025

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