임프란트 식립을 위한 골이식재

Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University, Korea

Abstract

A variety of grafting materials are available for use in implant dentistry. Sufficient bone is needed for the long-term stabil- ity of the implant, and the possibility of bone regeneration is currently more predictable than in the past. The bone materials are classified as follows: autogenous bone, allografts, xenografts, alloplasts. Autogenous bone is considered the gold stan- dard material because of its main properties: osteogenetic, osteoinductive, osteoconductive. However, disadvantages such as unpredictable resorption and donor site morbidity have led to the need for bone substitutes. Allografts harvested from cadaver and demineralized freeze-dried bone are not only osteoconductive but also osteoinductive. Xenografts are obtained from another species and possess osteoconductive potential. Alloplasts are a bone material that is synthetic or in a natural form and possess only osteoconductive capabilities. In this article, we analyze the properties of the bone grafting materials that are currently available and discuss their efficacy in implant dentistry.

Key Words: allograft, alloplast, autogenous bone, xenograft, implant (Implantology 2011; 15(1): 50~57)

Bone Grafting Materials for Implant Placement

Jin-Ha Kim, Su-Gwan Kim, Ji-Su Oh

임프란트 식립을 위한 골이식재

김진하, 김수관, 오지수

조선대학교 치의학대학원 구강악안면외과학교실

대한구강악안면임프란트학회지 15권 1호, 2011 51

서론

본론

1. Modes of mechanis

2. Ideal grafting materials & type of materials

Ⅱ

I

Review Articles

1) 자가골(Autogenous bone)

2) 동종골(Allobone)

대한구강악안면임프란트학회지 15권 1호, 2011 53

3) 이종골(Xenobone)

4) 합성골(Alloplastic materials)

Review Articles

대한구강악안면임프란트학회지 15권 1호, 2011 55

3. 골유도 성장 인자(Osteoinductive

growth factor)

참고문헌

1. Greenwald AS, Boden SD, Goldberg VM, et al. Bone-graft substitutes:

facts, fictions, and applications. J Bone Joint Surg Am. 2001; 83-A Suppl 2 Pt 2: 98-103.

2. Boyce T, Edwards J, Scarborough N. Allograft bone. The influence of processing on safety and performance. Orthop Clin North Am. 1999;

30: 571-581.

3. Khang G, Kim MS, Min BH, et al. Scaffolds for tissue engineering.

Tissue Eng Regen Med. 2006; 3: 376-395.

4. Urist MR. Bone: formation by autoinduction. Science. 1965; 150: 893- 899.

5. Urist MR. Bone transplants and implants. In: Urist MR, ed, Fundamental and clinical bone physiology. 1st ed. Philadelphia:

Lippincott Williams and Wilkins; 1980. p. 331-368.

6. Masters DH. Implants. Bone and bone substitutes. CDA J. 1988; 16: 56- 65.

7. Rejda BV, Peelen JG, de Groot K. Tri-calcium phosphate as a bone sub- stitute. J Bioeng. 1977; 1: 93-97.

Ⅲ

Review Articles

8. Hoexter DL. Bone regeneration graft materials. J Oral Implantol. 2002;

28: 290-294.

9. Gazdag AR, Lane JM, Glaser D, et al. Alternatives to autogenous bone graft: efficacy and indications. J Am Acad Orthop Surg. 1995; 3: 1-8.

10. McAuliffe JA. Bone graft substitutes. J Hand Ther. 2003; 16: 180-187.

11. Misch CE, Dietsh F. Bone-grafting materials in implant dentistry.

Implant Dent. 1993; 2: 158-167.

12. Marx RE, Saunders TR. Reconstruction and rehabilitation of cancer patients. In: Fonseca RJ, Davis WH, eds. Reconstructive preprosthetic oral and maxillofacial surgery. 1st ed. Philadelphia: WB Saunders;

1986. p. 347-428.

13. Second-hand bones? Lancet. 1992; 340: 1443.

14. Lane JM. Bone graft substitutes. West J Med. 1995; 163: 565-566.

15. Rummelhart JM, Mellonig JT, Gray JL, et al. A comparison of freeze- dried bone allograft and demineralized freeze-dried bone allograft in human periodontal osseous defects. J Periodontol. 1989; 60: 655-663.

16. Mellonig JT. Decalcified freeze-dried bone allograft as an implant mate- rial in human periodontal defects. Int J Periodontics Restorative Dent.

1984; 4: 40-55.

17. Tatum OJ Jr, Lebowitz MS, Tatum CA, et al. Sinus augmentation.

Rationale, development, long-term results. N Y State Dent J. 1993; 59:

43-48.

18. Fonseca RJ, Frost D, Zeitler D, et al. Osseous reconstruction of edentu- lous bone loss. In:Fonseca RJ, Davis WH, eds. Reconstructive prepros- thetic oral and maxillofacial surgery. 1st ed. Philadelphia: WB Saunders; 1986. p. 117-165.

19. Piattelli M, Favero GA, Scarano A, et al. Bone reactions to anorganic bovine bone (Bio-Oss) used in sinus augmentation procedures: a histo- logic long-term report of 20 cases in humans. Int J Oral Maxillofac Implants. 1999; 14: 835-840.

20. Valentini P, Abensur D. Maxillary sinus floor elevation for implant placement with demineralized freeze-dried bone and bovine bone (Bio- Oss): a clinical study of 20 patients. Int J Periodontics Restorative Dent.

1997; 17: 232-241.

21. Valentini P, Abensur D, Wenz B, et al. Sinus grafting with porous bone mineral (Bio-Oss) for implant placement: a 5-year study on 15 patients.

in the sinus area filled with different grafting materials. A histological study in beagle dogs. Clin Oral Implants Res. 1995; 6: 155-163.

24. Klinge B, Alberius P, Isaksson S, et al. Osseous response to implanted natural bone mineral and synthetic hydroxylapatite ceramics in the repair of experimental skull bone defects. J Oral Maxillofac Surg. 1992;

50: 241-249.

25. Hislop WS, Finlay PM, Moos KF. A preliminary study into the uses of anorganic bone in oral and maxillofacial surgery. Br J Oral Maxillofac Surg. 1993; 31: 149-153.

26. Park SH. A comparative study of basic characteristics of three depro- teinized bovine bone mineral as a bone graft substitute. Kyungbuk Uni- versity; 2009. p. 19-23.

27. Meffert RM, Thomas JR, Hamilton KM, et al. Hydroxylapatite as an alloplastic graft in the treatment of human periodontal osseous defects. J Periodontol. 1985; 56: 63-73.

28. LeGeros RZ. Properties of commercial bone grafts compared to human bone and new 'synthetic bone' biomaterials. In: Program and abstracts of the 9th annual meeting of the Society for Biomaterials. Birmingham, AL. 1983; Abstract 86.

29. Stahl SS, Froum SJ. Histologic and clinical responses to porous hydrox- ylapatite implants in human periodontal defects. Three to twelve months postimplantation. J Periodontol. 1987; 58: 689-695.

30. Fetner AE, Hartigan MS, Low SB. Periodontal repair using PerioGlas in nonhuman primates: clinical and histologic observations. Compendium.

1994; 15: 932, 935-938.

31. Frame JW. Hydroxyapatite as a biomaterial for alveolar ridge augmen- tation. Int J Oral Maxillofac Surg. 1987; 16: 642-655.

32. Crespi R, Capparè P, Gherlone E. Magnasium-enriched hydroxyapatite compared to calcium sulfate in the healing of human extraction sockets:

radiographic and histomorphometric evaluation at 3 months. J Periodontol. 2009; 80: 210-218.

33. Frame JW, Rout PG, Browne RM. Ridge augmentation using solid and porous hydroxylapatite particles with and without autogenous bone or plaster. J Oral Maxillofac Surg. 1987; 45: 771-778.

34. Boyne PJ. Advances in preprosthetic surgery and implantation. Curr

Opin Dent. 1991; 1: 277-281.

대한구강악안면임프란트학회지 15권 1호, 2011 57 1999; 30: 599-613.

38. Ahn JH, Choi SW, Kim MS, et al. Osteogenesis of stem cell using small molecule. Tissue Eng Regen Med. 2006; 3: 101-107.

39. Wozney JM. The potential role of bone morphogenetic proteins in peri- odontal reconstruction. J Periodontol. 1995; 66: 506-510.

40. Marx RE, Carlson ER, Eichstaedt RM, et al. Platelet-rich plasma:

Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998; 85: 638-646.

41. Rose LF, Rosenberg E. Bone grafts and growth and differentiation fac- tors for regenerative therapy: a review. Pract Proced Aesthet Dent.

2001; 13: 725-734.

42. Cochran DL, Wozney JM. Biological mediators for periodontal regen- eration. Periodontol 2000. 1999; 19: 40-58.

43. Boyne PJ. Bone induction and the use of HTR polymer as a vehicle for osseous inductor materials. Compend Suppl. 1988; (10): S337-341.

44. Boyne PJ, Scheer PM. Bone inductive effects of skeletal grown factor

with hydroxylapatite and synthetic matrices. Presented at American

Association of Oral and Maxillofacial Surgeons meeting. September,

1986; San Francisco, CA (Abstract).