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Synergistic Effects of Combination Therapy with AKT and mTOR Inhibitors on Bladder Cancer Cells

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Table 1. Molecular characteristics of seven bladder cancer cell lines.
Figure 3. Effects of the combination of an AKT inhibitor (AZD5363) and mTOR inhibitors (AZD2014  and  BEZ235)  on  the  proliferation  of  PI3KCA  and  mTOR-mutated  bladder  cancer  cells
Figure 4. Effects of the combination therapy with an AKT inhibitor (AZD5363) and mTOR inhibitors  (AZD2014 and BEZ235) on the apoptosis of PI3KCA and mTOR-mutated bladder cancer cells
Figure 5. Effects of the combination therapy with an AKT inhibitor (AZD5363) and mTOR inhibitors  (AZD2014  and  BEZ235)  on  the  invasion  and  expression  of  epithelial-to-mesenchymal  transition  (EMT)-regulating  genes  of  PI3KCA  and  mTOR-mutated

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