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Total gastrosplenectomy with distal pancreatectomy for local advanced gastric adenocarcinoma

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AHBPSAnnals of Hepato-Biliary-Pancreatic Surgery

www.ahbps.org S376

Total gastrosplenectomy with distal pancreatectomy for local advanced gastric adenocarcinoma

Erkin ASHIMOV*, Nikolay KISELEV, Hayk TORGOMAYN, Vladimir ZAGAINOV

Fuculty of Surgery and Transplantation, Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia

EP-177

Introduction: Surgical treatment the main option for local advanced gastric adenocarcinoma (LAGA). For tumors with invading on body and tail of pancreas, distal pancreatectomy (DPE) may be necessary to achieve negative margin resection (pR0). The aim of this study was to evaluate the short- and long-term outcomes of total gastrosplenectomy (TGSE) + DPE vs. TGSE for LAGC.

Methods: The retrospective analysis of patients who underwent TGSE + DPE and TGSE between January 2017 and December 2019 years in the Volga District Medical Center. The resection margin, postoperative complications, overall survival outcomes were ana- lyzed.

Results: 94 patients who underwent total gastrosplenectomy with or without distal pancreatectomy for LAGA were enrolled (72 TGSE and 22 TGSE-DPE). Histopathologic final analysis of TGSE + DPE group confirmed invasion (pT4b) in 63.6%. pR1 resection was in 13.6% vs. 2.8% in TGSE group (p = 0.082). Clavien-Dindo grade IIIb were observed 9.1% vs. 4.2% (p = 0.023). The 1-year overall sur- vival rate were 40.9% in TGSE + DPE vs. 90.3% in TGSE (p < 0.001).

Conclusions: Total gastrosplenectomy with distal pancreatectomy was associated with high pR1 resection and postoperative compli- cations; patients should be carefully selected because long-term survival remains poor.

pISSN: 2508-5778ㆍeISSN: 2508-5859

Ann Hepatobiliary Pancreat Surg 2021;25 Suppl 1:S376 https://doi.org/10.14701/ahbps.EP-177

Corresponding Author: Erkin ASHIMOV ([email protected]) Presenter: Erkin ASHIMOV ([email protected])

Copyright Ⓒ The Korean Association of Hepato-Biliary-Pancreatic Surgery

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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