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Role of Cyclooxygenase Isoforms in Peripheral Neuropathic Pain Model

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Fig. 1. The time course of mechanical hyperalgesia in rats with L5 spinal nerve  ligation
Fig.  2.  Effect  of  COX  inhibitors  on  the  maintenance  of  neuropathic  pain.    In  rats  with  spinal  nerve  ligation,  mechanical  thresholds  were  measured  (SNL)  after  vehicle  and  nimesulide  injection
Fig.  3.  The  immediate  effect  of  COX  inhibitors  on  neuropathic  pain.  The  %  of  response  presents  percentage  of  changing  the  thresholds  from   pre-treated  state
Fig.  4.  Expression  of  COX  isoforms  mRNA  in  the  dorsal  root  ganglia  with  spinal nerve ligation
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