[PDF] Top 20 Vinpocetine inhibits the proliferation and induces apoptosis in human colon cancer cells
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Vinpocetine inhibits the proliferation and induces apoptosis in human colon cancer cells
... 다음으로 vinpocetine을 처리한 HCT116 세포에서 세포주기 조 절 및 세포자멸사 관련 인자들의 발현 변화를 ...세포를 vinpocetine 함유 배지에서 다양한 시간대로 배양하 여 세포주기 조절에 관련된 유전자의 발현 정도를 ...발현이 vinpocetine 처리의 48시간 배양에서 증 가하였다. 이러한 결과들을 통해 ... See full document
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Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts
... advances in understanding the carcinogenesis of colorectal cancer, the increasing incidence and relatively low remission rate of chemotherapy have spurred researchers to develop more ... See full document
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Delphinidin inhibits cell proliferation and induces apoptosis in MDA-MB-231 human breast cancer cell lines
... 단백질 발현 세포 성장, 세포 사멸과 관련된 단백질 발현을 알아보기 위 해 western blot을 실시하였다. MDA-MB-231 cell을 5 × 10 5 cells/mL의 농도로 100 mm dish에 분주하고 48시간 후에 SFM 으로 교환하여 세포를 starvation하였다. 24시간 후 SFM에 delphinidin을 0, 5, 10, 20 μmol/L로 농도로 ... See full document
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20-O-(β-D-glucopyranosyl)-20(S)-protopanaxadiol induces apoptosis via induction of endoplasmic reticulum stress in human colon cancer cells
... K induces phosphorylation of PERK and eIF-2 α ; ii) Compound K induces phosphorylation of IRE-1 and the spliced XBP transcription factor; iii) Compound K induces cleavage of ... See full document
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A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells
... active in biological systems and inhibits glucose uptake in tumor ...metastasis in vivo, and constrains tumor growth through the inhibition of 12-O-tetradecanoylphorbol- ... See full document
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Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells
... arrest and induces apoptosis via activation of MAPK in human pancreatic cancer ...thymoquinone-induced apoptosis and activate ERK and JNK ... See full document
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ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells
... of proliferation. Overall, the ERBB3 blockade resulted in anti- tumorigenic effects without altering the PI3K/AKT/mTOR pathways in HCT116 cells by inhibiting cell ... See full document
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INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis
... Ino80, the catalytic ATPase of the INO80 complex, decreased intestinal adenomatous polyps and increased survival in an Apc min/+ mouse model of colon ...mice and cells ... See full document
13
The chloroform fraction of <italic>Citrus limon</italic> leaves inhibits human gastric cancer cell proliferation via induction of apoptosis
... “BFLL” and water fraction of lemon leaves “WFLL”), several cancer cells were treated with various concentrations of each ...treating human breast cancer cell line MDA-MB-231 (Fig. 1A), ... See full document
7
Artemisia capillaris Thunb. inhibits cell growth and induces apoptosis in human hepatic stellate cell line LX2
... MEK and ERK protein were detected by Western blot ...capillaris induces cell cycle arrest, apoptosis, and potently inhibits the mitogen-activated protein kinase ...cell ... See full document
9
Juniperus chinensis extract induces apoptosis via ROS generation in human pancreatic cancer cell lines
... JCX inhibits cell viability in human pancreatic cancer cell ...shown in Fig. 1. The WST assay was conducted to examine whether the JCX mediates the inhibition effects on ... See full document
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A new anti-proliferative drug induces mitotic arrest and apoptosis in human pancreatic cancer cell lines
... TP53, and SMAD4, are the most important events associated with malignant transformation of pancreatic ...mutated in almost 90% of pancreatic cancer patients and the mutation is ... See full document
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Bee venom inhibits the proliferation and migration of cervical-cancer cells in an HPV E6/E7-dependent manner
... significantly induces apoptosis in HPV-positive cervical-cancer cells To further investigate whether BV affects cell fate, we carried out PI staining analysis after treating Caski ... See full document
6
Methanol extracts of Asarum sieboldii Miq. induces apoptosis via the caspase pathway in human FaDu hypopharynx squamous carcinoma cells
... that the anti-cancer effect of methanol extract of ...sieboldii inhibits the cell growth and induced cell apoptosis in FaDu cells through extrinsic death receptor ... See full document
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<i>Juniperus chinensis</i> extract induces apoptosis via reaction oxygen species (ROS) generation in human pancreatic cancer cell lines
... (JCX) inhibits cell viability and migration in human pancreatic cancer ...levels and regulates the FAK/ERK pathway and apoptosis-related proteins, suggesting ... See full document
6
18α-Glycyrrhetinic acid induces apoptosis of AGS human gastric cancer cells
... Key words : 18α-Glycyrrhetinic acid, Human gastric adenocarcinoma cell, AGS, Anti-cancer. Ⅰ. 서론 a) 암은 전 세계에서 가장 생명을 위협하는 질병 중 하나이며 그 중에서 위암은 세계에서 두번째로 암과 관련된 사망 원인이다 1,2) . 위암은 매년 거의 100만 명 의 새로운 환자에게서 진단되고 있으며, ... See full document
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Porphyra tenera induces apoptosis of oral cancer cells
... 과학과 의학기술의 발전으로 암(癌)은 완치율이 점차 높아 지고 있지만, 여전히 한국인의 대표적인 사망원인중 하나이다. 2014년 발표된 중앙암등록본부 자료에 따르면 2011년 우리 나라에서 발생한 전체 암 중에서 구강암은 약 0.2%의 비율을 차지하고 있는 희귀 암으로, 그 예후가 좋지 못하며 5년 동안 생존율도 50%에 불과하다고 알려져 있다 14) . 치료를 위해 외 과수술, 방사선 ... See full document
6
Salinomycin inhibited cell proliferation and induced apoptosis in human uterine leiomyoma cells
... vary in size and number, and are mostly slow-growing with no ...toms and need medical treatment [1]. Myomas may grow as a single nodule or in clusters and range in size ... See full document
6
The effect of β-sitosterol proliferation and apoptosis in human uterine leiomyoma cells
... in human uterine leiomyoma cells Youngsun Park, Seunghee Baek. Dept.[r] ... See full document
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BML-275, an AMPK inhibitor, induces DNA damage, G2/M arrest and apoptosis in human pancreatic cancer cells
... Cancer cells usually exhibit increased levels on intracel- lular ROS, which in turn can initiate various cycles leading to further metabolic malfunction and ROS generation ...lipids and other ... See full document
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