Top PDF Role of Bcl-xL in Doxorubicin-Induced Cell Death: Apoptosis and Mitotic Cell Death
Caffeine-induced endothelial cell death and the inhibition of angiogenesis
... Department of Anatomy, Chungbuk National University Medical School, Cheongju, Korea, 2 Department of Hematology, Affiliated Hospital of Yanbian University, Yanji, China, 3 Department of ...
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Role of inducible heat shock protein 70 in radiation-induced cell death
... Cell death To study whether shortened G2/M phase arrest and al- tered response of cell cycle–related protein expressions by hsp70 could affect radiation-induced cell ...
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The switching role of beta-adrenergic receptor signalling in cell survival or death decision of cardiomyocytes
... range of ISO followed by a further decrease to below its basal level (B50%) in a micromolar concentration range ...mitochondrial apoptosis and necrosis 26,27 , and the survival effect ...
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Cell death map in drug-induced ototoxicity: apoptosis, autophagy, and necroptosis
... 내재적 아포토시스는 미토콘드리아를 매개로 caspase-9 이 활성화됨으로써 유도되며 이 경로의 주 조절자는 BCL-2 family 단백질들이다. BCL-2 family 는 BH3-only 단백질 (Bim, Bid, Noxa 등), BCL-2 (혹은 BCL-xL, MCL1), 미토콘드리아 pore (MOMP, mitochondria outer membrane pore)를 생성하는 BAX 와 ...
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Cyclosporin A aggravates hydrogen peroxide–induced cell death in kidney proximal tubule epithelial cells
... Program in Advanced Convergence Technology & Science, Jeju National University, Jeju, 2 Department of Anatomy, Jeju National University School of Medicine, Jeju, Korea Abstract: Cyclosporin A (CsA) ...
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Outcome of triple-negative breast cancer in patients with or without markers regulating cell cycle and cell death
... inhibit apoptosis and therefore relate to a worse outcome ...expression of bcl-2 in breast cancer has been found to be associated with favor- able prognostic factors such as small tumor ...
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Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer
... IGFBP-3- induced Growth Inhibition and Apoptosis—To determine whether IGFBP-3R mediates antiprolifera- tive effect of IGFBP-3, the growth inhibitory actions of endogenous IGFBP-3 via IGFBP-3R ...
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A new anti-proliferative drug induces mitotic arrest and apoptosis in human pancreatic cancer cell lines
... induces mitotic arrest by regulating cell cycle-related proteins in human pancreatic cancer cells To investigate whether #765-induced inhibition of cell proliferation was caused ...
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Calcium overload is essential for the acceleration of staurosporine-induced cell death following neuronal differentiation in PC12 cells.
... Differentiation of neuronal cells has been shown to ac- celerate stress-induced cell death, but the underlying mechanisms are not completely ...early and sustained increase in ...
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Morusin induces cell death through inactivating STAT3 signaling in prostate cancer cells
... because of its constitutive activation in this fatal ...bark of Morus alba ...used in Korea. Morusin, an active compound isolated from the root bark of Morus alba, has shown ...
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BCL2 antagonist of cell death kinases, phosphatases, and ovarian cancer sensitivity to cisplatin
... CP cell line ...important in determination of cisplatin-induced apoptosis, likely via the phosphorylation status of the BAD protein, there are multiple other molecular mechanisms ...
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Tannic acid-induced apoptosis in FaDu hypopharyngeal squamous cell carcinoma
... µM of TA for 24 hours caused 80% of cell death ...acid induced cell cycle arrest and apoptosis Flow cytometry was used to examine the cell cycle distribu- ...
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The role of microRNAs in cell death pathways
... summarized and discussed how miRNAs regulate apoptosis, ER stress, necroptosis, and autophagy by target- ing a wide range of components of these pathways and document- ed the ...
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Mechanism of ethanol-induced purkinje cell death in developing rat cerebellum: Its Implication in apoptosis and oxidative damage
... ability of oxidative stress to provoke necrotic cell death as a résu1ï of massive cellular damages associated t 。 1ipid peroxidation18) and a1teration of proteins20) and ...
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A pattern of cell death induced by 40 kHz ultrasound in yeast cell model
... Keywords: Cell death, 40 kHz ultrasound, yeast, Reactive oxygen species PACS numbers: 43.35.Wa., 43.80.Gx 초 록: 초음파는 세포사멸을 포함하여 의학 및 생물학분야에 널리 응용되고 있으나 그 정확한 기작에 대해선 논쟁의 여지가 있다. 본 연구에서는 40 kH 초음파 조사시스템을 단세포 효모에 ...
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Protection effect of EC on radiation-induced cell death of auditory cell in vitro and in vivo
... 청 청각 각 각세 세 세포 포 포사 사 사멸 멸 멸에 에 에 대 대 대한 한 한 녹 녹 녹차 차 차추 추 추출 출 출 E E Ep p pi i ic c ca a at t te e ec c ch h hi i in n n의 의 의 보 보 보호 호 호효 효 효과 과 과 방사선은 현재 암 치료용으로 널리 사용되고 있으며 특히 두경부암의 경 우 생명을 유지시키는데 중요한 장기와 구조물이 ...
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CIIA is a novel regulator of detachment-induced cell death.
... Detachment-induced cell death, or anoikis, is a type of apoptosis that occurs when epithelial cells lose their attachment to the extracellular ...mechanism of ...
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The Role of PKC-δ in Hypoxia-induced Cerebrovascular Endothelial cell death.
... 3 뇌혈관 세포주를 저산소에 노출시킨 지 1 시간째 PKC-δ의 활성 가장 증가하였고 4시간까지 지속되었다.저산소에 의한 뇌혈관 내피세포 사멸과 정에서 PKC-δ의 역할을 알아보기 위해 PKC-δ 저해제인 rottl eri n을 처리한 결 과,저해제의 농도가 증가함에 따라 세포 사멸이 현저히 증가하였으며 저산소 자 극 후 PKC-δ[r] ...
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Gangliosides induce autophagic cell death in astrocytes
... tion and volume of the extracellular space change, thereby slowing down the movement of various molecules and increasing their local concentrations at injured sites (Sykova, ...concentration ...
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Role of RIP3 in DNA damaging agent-induced breast cancer cell death
... al and t he r ape ut i c c ons e que nc es ,i nc l udi ng pos si bl e e f f ec t s on t he r e s pons es oft umorc e l l s t o c he mot he r ...on and wewi l li nve s t i gat ehow t het umorsuppr e s sorr ...
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