[PDF] Top 20 Production and characterization of monoclonal antibodies against cathepsin B and cathepsin B-Like proteins of Naegleria fowleri
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Production and characterization of monoclonal antibodies against cathepsin B and cathepsin B-Like proteins of Naegleria fowleri
... 외국의 경우 파울러자유아메바는 토양, 습지, 강, 연못 등에서 서식하는데 염소를 처리한 수영장이나 물온도가 높은 온천에서도 분리배양된다(Sheehan et al., 2003). 파울러자유아메바의 병인기전은 크게 접촉성 병인기전과 비접촉성 병인기전이 있으며 이러한 병인기전을 통해 숙주세포를 죽음에 이르게 한다 (Kim et al., 2008). Cysteine protease 계열의 단백질인 ... See full document
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Characterization of cathepsin B cysteine protease from Naegleria fowleri excretory-secretory proteins exerting immunomodulatory effects
... Conclusion Naegleria fowleri causes a lethal PAM in humans and experimental animals, which leads to death within 7-14 ...proteases of parasites play key roles in nutrient uptake, ... See full document
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Production and Characterization of Monoclonal Antibodies against a Recombinant Nfa1 Protein Cloned from Pathogenic Naegleria fowleri
... 본 연구자의 연구실에서는 병원성 파울러자유아메바의 cDNA l i brary를 구축 하여 파울러자유아메바에 대한 감염혈청 및 면역혈청으로 i mmunoscreeni ng과정 을 통해 항원성과 관련이 있고 특히,위족에 특이성이 있는 유전자를 클로닝하여 nf a1이라 명명하였다 (Shin 등,2001).이 유전자는 357개의 염기로 구[r] ... See full document
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갑상선 미세유두선암에서 Cathepsin B 의 발현
... 군에서 cathepsin B 의 발현이 낮았고 특히 외측 , 림프절 전이가 있었던 예 중 예에서 9 7 cathepsin B 가 양성 으로 나와 외측 림프절 전이와 cathepsin B 양성 사이에 연관이 있는 것을 시사해 주었다 경부의 외측부는 해부 ... See full document
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Molecular Analysis and Enzymatic Characterization of Cathepsin B from Olive Flounder (Paralichthys olivaceus)
... 왔으며 Cathepsin B 는 단백질 분해의 초기과정에 관여하는 cysteine proteases 중 하나이다 본 연구는 ...넙치의 cathepsin B 유전자의 발현 양상과 넙치 cathepsin B(PoCtB) 의 클로닝 발현 및 효소특성을 분 , 석하였다 ... See full document
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Production and Physico-chemical Properties of Cathepsin B Inhibitor from Streptomyces aburabiensis SMF30
... Cathepsin B 저자물질의 발효생산 및 특성분석 307 요로 한다. 일반적으로 비장에 가장 많이 존재하며. 훈 선. kidney, 간 . 페 등에서도 발견되는 cathepsin B 는 여러가지 병발작용에 관련되어 있다고 여겨지고 있어 근육실조, 암전이, 심근손상, 염증. 골 다 공 중 , 그 리 고 다른 여러 clinical ... See full document
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Isolation and Identification of Streptomyces aburabiensis Producing Cathepsin B Inhibitor
... 결 론 전국각지에서 수집된 토양시료를 여러가지 방법으로 전처러하고 방선균 분러용 배지를 사용하여 얻어진 약 700여종의 방선균으로부터 여러가지 병리작용에 관여 한다고 알려진 Cathepsin B 에 대한 저분자량외 저해 물질을 생산하는 균주틀 검색한 결과. 생산하는 저해물 질외 Cathepsin B 에 대한 톡이성. 역가. 열에 대한 안 ... See full document
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Production and characterization of monoclonal antibodies against an avian influenza virus (H9N2)
... viral proteins of a Korean field isolate to decrease the mismatches be- tween MAbs and viral ...NP- and NS1-specific MAbs reacted to all other subtypes of AIVs in this ...tural ... See full document
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Production of recombinant monoclonal antibodies against HSET
... analysis of anti-HSET mAbs Sequence of mAbs were analyzed for the generation or enginieering of recombinant ...sequences of all mAbs were analyzed regardless of their binding ... See full document
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Production of monoclonal antibodies against marine birnavirus
... Oh and Wi-Sik Kim † Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, Yeosu 59626, Korea We developed and subsequently characterized ... See full document
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Generation and Characterization of Monoclonal Antibodies against Human Interferon-lambda1
... mechanisms of their action have remained ...endocytosis of IFN- λ , we produced monoclonal antibodies (Abs) against human IFN-λ and examined their ...activity of the ... See full document
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Production and diagnostic applications of monoclonal antibodies against porcine circovirus
... Production and diagnostic applications of monoclonal antibodies against porcine circovirus Kyung-Mi Kim, Ji-Hye Jeong, Hong-Ki Min, Seung-Chul Lee, In-Soon Roh1, and Shien-Young Kang* Re[r] ... See full document
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Cathepsin B Is Implicated in Triglyceride (TG)-Induced Cell Death of Macrophage
... 경로와 cathepsin B와의 연관성에 대해 연구하였다. cathepsin B 억제시 caspase-7, -8 및 -1의 활성은 억제되었으나, caspase-3, -9 및 -2는 활성에는 영향을 미치지 않음을 알 수 ...방출된 cathepsin B는 caspase-1 활성화에 기여하고, 활성화된 caspase-1은 외 인성 ... See full document
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Production and diagnostic application of monoclonal antibodies against infectious bursal disease virus
... Infectious bursal disease (IBD) caused by infectious bursal disease virus (IBDV) is a highly contagious viral disease in chicken.. It causes heavy economic loss by immune suppression an[r] ... See full document
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Characterization of Monoclonal Antibodies against Human Leukocyte Common Antigen (CD45)
... immunohistochemistry, and immunoprecipitation, we evaluated the reactivity of those mAbs to CD45 of thy- mus as well as tonsil ...each of gene constructs that express five human CD45 isoforms ... See full document
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Resistance to Chemotherapy on Tumor Through Cathepsin B -dependent Activation of the NLRP3 Inflammasome
... Kwon and Young-Sang Koh * Jeju National University School of Medicine, Jeju, Korea Anticancer drugs kill tumor cells and increase host anti-tumor ...(Gem) and 5-fluorouracil (5-FU), widely ... See full document
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Establishment of B-1 cell-derived polyreactive monoclonal antibodies and expression of costimulators by B-cell to antigenic stimulation
... 비장 B 세포의 동시자극자의 발현을 Fluorescence Activated Cell Sorting (FACS)을 이용하여 ...이 B-1 세포 유래 단 클론 항체는 dose-saturable pattern을 띄는 다중 반응성을 ...비장의 B 세포가 유사하였으나, B7-1 과 7-2는 복강의 B 세포에서 더 뚜렷한 발현을 ... See full document
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Production of Monoclonal Antibodies Against Nervous Necrosis Virus (NNV, RGNNV genotype)
... genotype, Monoclonal antibody This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Licens ...distribution, and reproduction in any medium, ... See full document
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Characterization of antiphospholipid antibodies in chronic hepatitis B infection
... rily and disappear within 2 or 3 months [24, 25], and except in rare cases, they are unrelated to thrombotic ...Ab and β 2 GPI Ab showed persistence and were present over a 12-week ...aPL ... See full document
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Production of monoclonal antibodies against VP28 of white spot syndrome virus (WSSV)
... 46 방지형 · 김위식 · 김춘섭 · 김종오 · 오명주 이용한 면역학적인 방법(enzyme-linked immun- osorbent assay (ELISA), indirect fluorescent anti- body test, immunohistochemistry 등), 병리조직학적 방법 등이 사용되고 있다 (OIE, 2017). 이들 검사 방법 중, PCR과 병리조직학적 검사 방법은 국내 ... See full document
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