[PDF] Top 20 Neuronal Changes in Lactate Dehydrogenase B Deficiency Mice
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LDHB deficiency ameliorates ischemic neuronal cell death
... increased in LDHB deficiency under ischemic condition and how PcomA size is ...is in close connection with ischemic cell death (Michelle et ...of neuronal cells, according to ... See full document
46
Isocitrate dehydrogenase 2 deficiency aggravates prolonged high-fat diet intake-induced hypertension
... +/+ mice, suggesting that IDH2 protects mitochondria against HFD-induced mitochondrial ...expression in kidney proximal tubule cells, whereas treatment with MnSOD mimetic inhibits AGT mRNA expression ... See full document
10
Mitochondrial NADP(+)-dependent isocitrate dehydrogenase deficiency increases cisplatin-induced oxidative damage in the kidney tubule cells
... resulting in the release of cytochrome c to the cytosol 34 ...increases in Drp1 and Bax ...greater in Idh2 ‒/‒ mice than in wild-type ...stress in Idh2 ‒/‒ mice is ... See full document
13
Accelerated lactate dehydrogenase activity potentiates osteoclastogenesis via NFATc1 signaling
... of lactate dehydrogenase (LDH), a tetrameric enzyme consisting of an A and/or B subunit that catalyzes interconversion of pyruvate to lactate, in RANKL-induced osteoclast differentiation is ... See full document
13
Lactate dehydrogenase deficiency increases methylglyoxal and induces cardiomyopathy
... I. Methylglyoxal Determination by ELISA The methylglyoxal was quantified using Competitive ELISA (Cell biolabs, STA-811, OxiSelect™ Methylglyoxal (MG) Competitive ELISA Kit), according to the manufacturer's ... See full document
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The prognostic significance of serum lactate dehydrogenase-to-albumin ratio in colorectal cancer
... prognosis in CRC, based on the high LDH and low albumin levels associated with poor prognosis in many ...prognosis in CRC patients undergoing curative ...study in the literature investigating ... See full document
10
GABAergic neuronal development in the embryonic mesencephalon of mice
... and neuronal migration patterns of gamma-aminobutyric acid-ergic (GABAergic) neurons during mesencephalic development of ...generated in the mesencephalic region at E10 to ...only in the dorsal ... See full document
5
Control of neuronal migration through rostral migratory stream in mice
... generated in the neurogenic niche located near the ventricle, and the newly generated cells actively migrate toward their destination, olfactory bulb, via highly specialized migratory route called rostral ... See full document
11
Ninjurin1 deficiency Attenuates Susceptibility of Experimental Autoimmune Encephalomyelitis in mice
... Expression in the BMDMs and Raw264.7 Cells Is Directly Involved in Their TEM Activity across an MBEC4 Monolayer—Through previous and our current studies with blocking antibody or peptide, it has already ... See full document
12
CCR5 deficiency in aged mice causes a decrease in bone mass
... tissue in elderly patients are ...KO mice, and microcomputed tomography and histology analyses were ...KO mice exhibited a decreased trabecular bone mass and cortical bone thickness in both ... See full document
9
A study on the effect of freezing rate on catalytic activity and molecular structure of L-lactate dehydrogenase
... pattern in the visible range, even if excited in the UV region (Breydo & Uversky, ...observed in amyloid aggregates which have a high proportion of β-sheets (Chan, Kaminski Schierle, Kumita, ... See full document
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The investigation of locus coeruleus noradrenergic neuronal circuitry change and neuronal plasticity after permanent focal cerebral ischemia in mice using genetic tracing method
... β-galactosidase in NA neurons upon its microinjection to LC, 38 which was in agreement with successful visualization of NA system in mouse brain with recombinant adenoviral vector expressing WGA ... See full document
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Adult T-cell leukemia/lymphoma and Glucose-6-phosphate dehydrogenase deficiency rapidly diagnosed through blood smear examination
... 76 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, ... See full document
1
AHNAK deficiency promotes browning and lipolysis in mice via increased responsiveness to beta-adrenergic signalling
... progenitors in AHNAK deficiency still remains to be determined and traced in ...adipocytes in WAT 17,38 ...investigated in clin- ical trials and have shown improved bioavailability and ... See full document
10
Therapeutic potential of kakkalide for their anti-stroke and anti-hyperlipidemic effects: Biological importance of lactate dehydrogenase (LDH) and HMG-CoA reductase in medicine
... EP-94 Introduction: Kakkalide have been isolated from the flower of Pueraria thunbergiana is metabolized into irisolidone by human in- testinal microflora. Pueraria thunbergiana is a plant of Leguminosae family ... See full document
1
Effects of vitamin A deficiency on age-related and noise-induced sensorineural hearing loss in mice
... A deficiency (VAD) has an impact on more than 20% of preschool children and 10% of pregnant women in many developing countries, such as Africa and southern and central ...impairment in Japanese ... See full document
39
Iron-fortified recombinant Saccharomyces cerevisiae producing Sus scrofa ferritin heavy-chain recovers iron deficiency in mice
... observed in hemoglobin value and hematocrit ratio between APO and FER treatment, although each administration did signifi- cantly restores these ...control mice group although no iron was ...involved ... See full document
6
Highly elevated serum lactate dehydrogenase is associated with central nervous system relapse in patients with diffuse large B-cell lymphoma: Results of a multicenter prospective cohort study
... involvement in newly diagnosed DLBCL patients receiving R-CHOP who were registered the prospective ...relapse in enrolled patients, and evaluated CNS involvement at diagnosis from patients at risk with CSF ... See full document
11
Inhibitory effects of tilianin on the expression of inducible nitric oxide synthase in low density lipoprotein receptor deficiency mice
... knockout mice compared to littermate ApoE-/- controls (Detmers et ...ed in the atheromatous lesion, and tilianin effectively reduced NO synthesis in vitro or in vivo, suggesting that the ... See full document
9
Effects of 18β-glycyrrhetinic acid on pro-inflammatory cytokines and neuronal apoptosis in the hippocampus of lipopolysaccharide-treated mice
... 이전 in vitro 연구에서 보고된 18betaGA의 항염증 작용기전 및 본 연구의 in vivo 결과들을 종합해보면 18betaGA는 중추신경계에 대한 항염증 작용으로 신경세포손 상에 대한 보호작용은 물론 대뇌피질과 해마 신경세포의 손상과 시상하부의 염증반응에 의한 질병행동의 개선 등에도 유의한 효능이 있을 것으로 ... See full document
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