[PDF] Top 20 Identification of Undifferentiated Human Embryonic Stem Cell-Specific Genes
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Identification of Undifferentiated Human Embryonic Stem Cell-Specific Genes
... (지도교수 : 이 명 애) 포유류의 배반포에서부터 유래한 배아줄기세포는 늙지않고 다능성을 지니며 체세포나 생식세포등의 모든 형태로 분화가 가능하다. 최근 연구결과에 의하면 Pou5F1(Oct4, Oct3/4), Sox2, Nanog, LIN28, KLF4, Myc(c-Myc) 과 같은 유전자들이 배아줄기세포의 미분화상태를 유지시켜준다. 어떠한 메커니즘으로 인 해 미분화상태가 유지되어지는지 ... See full document
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Identification of Undifferentiated Embryonic Cell Transcription Factor 1 as a Potential Substrate of Carboxyl-Terminal Domain Small Phosphatases
... structures of CTDSP1 ...structures of a dominant- negative form of human CTDSP1 bound to mono- and di- phosphorylated peptides (PDB ID: 2GHQ and 2GHT) encom- passing the CTD heptad repeat in ... See full document
6
Characterization of Genes Specifically Expressed in Embryonic and Cancer Stem Cells
... Cancer cell is also an important research object because it cannot be conquered yet since we have been studying it for long ...out of control, develop abnormal size and shapes, ignore their typical ... See full document
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Epigenetic modification of retinoic acid-treated human embryonic stem cells
... Department of Genetic Epidemiology, SNP Genetics, ...Institute of Bioscience and Biotechnology, Daejeon 305-806, 3 Department of Biological Sciences and Center for Stem Cell ... See full document
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Establishment of Functional Cells for Vascular Defect Disease from Human Embryonic Stem Cell via Region Sorting Depending on Cell Volume
... 2011 Human embryonic stem cells have been highlighted as a valuable cellular source in the regenerative medicine field, due to their ...challenge of the establishment of specific ... See full document
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Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes
... from human PSCs are valuable tools for drug discovery and hepatotoxic- ity ...DME genes are inactive prior to birth [17,18]. Among DME genes, CYP enzymes play a role in the biotransformation ... See full document
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Differentiation of Human Embryonic Stem Cells into Germ Cell and Culture Condition for Single Embryonic Stem Cells Dissociated by Enzyme
... single cell 농도를 달리하여 feeder cell 위 에 seeding한 결과, 농도에 따라 colony formation rate는 차이를 나타내지 ...사용되는 stem cell marker인 alkaline phosphatase (AP)로 염색하여 colony 수를 ... See full document
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Efficient Induction of Oligodendrocytes from Human Embryonic Stem Cells
... terms of myelination activity, the oligodendrocyte precursor cells were cocultured with hippocampal neurons ...brains of 18-day-old rat fetuses, treated with trypsin, and dissociated by ...concentration ... See full document
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인간 배아줄기세포 확립에 따른 문제점 P roblems Associated with Establishment of Human Embryonic Stem Cell
... 경우에따라서는 아주 작은크기의 내세포괴를 갖고 있거 나, 혹은내세포괴를확인하기어려운경우도있다. 이미 설명한 바와 같이 면역학적 수술방법은 배아줄기 세포확립을 위해서 가장 흔히 사용되는 방법이지만 단점 으로는내세포괴의크기가 작은 경우또는 내세포괴의 존 재를 확인할 수없는 경우에는 실험과정에서내세포괴를 표 1. The advantages and disadvantages of each ... See full document
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Analysis of Trans-splicing Transcripts in Embryonic Stem Cell
... nalysis of Trans-splicing Transcripts in Em bryonic Stem C ...Department of Biological Sciences, College of Natural Sciences, Pusan National University, 1 National Primate Research Center, ... See full document
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Human Amniotic Fluid Cells Support Expansion Culture of Human Embryonic Stem Cells
... Cheng 등 10 은 성체골수세포를 직접 분리 및 배 양하여 영양 세포층으로 이용하여 인간배아줄기세 포의 성공적인 배양을 보고하였다. 그리고 mitomycin C 처리한 골수세포와 처리하지 않은 골수세포를 영양 세포층으로 이용하여 인간배아줄기세포를 배 양하여 그 결과를 비교하였는데, mitomycin C 처리 하지 않은 세포에서 배양된 인간배아줄기세포군이 더 좋은 성장률과 촘촘한 세포 ... See full document
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In Vivo Differentiation of Mouse Embryonic Stem Cell into Hepatocytes
... amount of cellular storage of glycogen, indicating that a given area is populated with hepatic cells in varying stages of ...organogenesis of embryo, the liver bud formed by the proliferation ... See full document
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Studies on the Function of Stromal Cell for Embryonic Stem Cell Growth and Decidual Differentiation
... physiology of decidualization The mouse blastocyst reaches the uterus four days after fertilization and attaches to the uterine epithelium on Day ...4.5 of pregnancy. This attachment of the ... See full document
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Establishment of Immortal Neuronal Stem Cell Line from Embryonic Day 17 Rat Brain
... expression of neuronal stem cell marker, ...infection of neural progenitor cells transplanted into embryos differentiated into neurons, oligodenderocytes, and ...Nestin-positive cell ... See full document
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Statistical Analysis about Ability to Mouse Embryonic Stem Cell Differentiation using cDNA Microarray
... <표 2>와 같았다. 경로분석은 총 3개의 모델을 가정하여 분석하였고, 3개의 모델 중 모델의 적합도를 나타내는 root mean squared residual과 good of fit index로 최종 모델을 선택하였다(root mean squared residual=0.02, good of fit index=0.92). 우선, 미지의 유전자인 ESTs와 ... See full document
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줄기세포는 배아줄기세포 (embryonic stem cells), 성체
... potential of CD271-MSCs. (a) Condensation behaviors of CD271-MSCs in micromass culture were examined using phase contrast images during culture for 3 days under ES (10 V/cm, 10 ms, ...levels of ... See full document
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Contralaterally transplanted human embryonic stem cell-derived neural precursor cells (ENStem-A) migrate and improve brain functions in stroke-damaged rats
... models of stroke, the transplantation of neural precursor cells (NPCs) has been shown to be a promising approach to ameliorate behavioral ...neural stem cells isolated from human fetal cortex, ... See full document
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A New Efficient Cryopreservation of Human Embryonic Stem Cells by a Minimum Volume Cooling Method
... expansion of hES cell colony on an STO cell feeder layer and complete survival which spend the same number of days as growing condition of non- frozen hES cells on STO cell as ... See full document
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Effects of Schisandrae Fructus 70% Ethanol Extract on Proliferation and Differentiation of Human Embryonic Neural Stem Cells
... Fructus, Human Embryonic Neural Stem Cells, Proliferation, Neuronal Differentiation, BDNF 파킨슨병, 알츠하이머병과 같은 퇴행성 뇌질환이나 뇌졸 중은 공통적으로 신경세포의 사멸에 의해 ... See full document
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Construction of Transgenic Silkworms Expressing Human Stem Cell Factor (hSCF)
... 유래 Stem Cell Factor ( h SCF) 재조합단백질이 발현되는 누에형질전환체 제작 김성완 1 ․윤은영 1 ․김성렬 1 ․박승원 1 ․강석우 1 ․권오유 2 ․구태원 1 * ( 1 국립농업과학원 잠사양봉소재과, 2 충남대학교 의과대학 해부학과) 본 연구의 목적은 누에형질전환체를 이용하여 재조합단백질 대량생산 시스템을 개발하는 것으로서, 본 실험에 서는 ... See full document
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