Toll-like receptor 4
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Lack of toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia
... of Toll-like Receptor 4 and 2 Polymorphisms in Korean Patients with Bacteremia Toll-like receptors (TLRs) are pattern-recognition receptors that are important in in- nate immune ...
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Toll-like Receptor 4-mediated Apoptotic Cell Death in Primary Isolated Human Cervical Cancers
... Toll-like receptor 4 (TLR4) has been implicated in cell proliferation and apoptosis in several types of cancer. In this study, the impact of TLR4 activation on apoptotic cell death in ...
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Hypoxia Activates Toll-like Receptor 4 Signaling in Primary Mouse Hepatocytes Through the Receptor Clustering within Lipid Rafts
... Hepatic ischemia/reperfusion (I/R) injury is largely related to innate immunity via Toll-like receptor 4 (TLR4) signaling. However, the mechanism by which hypoxia could lead to activate TLR4 ...
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1. p. 159 Effect of Staphylea bumalda Leaf Extracts on Macrophage Activation through Toll-Like Receptor 2 and Toll-Like Receptor 4-dependent c-Jun N-terminal Kinase Activation
... 유주형 4 · 최민영 5 · 이재원 6 · 백정규 7 · 정진부 8† Effect of Staphylea bumalda Leaf Extracts on Macrophage Activation through Toll-Like Receptor 2 and Toll-Like Receptor ...
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Protein Kinase $C-{\alpha}$ Regulates Toll-like Receptor 4-Mediated Inducible Nitric Oxide Synthase Expression
... that toll-like receptor 4 is the LPS recep- tor and mediates LPS-induced activation of downstream signaling pathways and expression of inflammatory tar- get genes 3) ...
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Interaction of Der p 2 with Toll-like Receptor 4 and its Effect on Cytokine Secretion
... Der p 2, which is a major allergen of house dust mite, plays an important role in the pathogenesis of allergic disease. There is controversy regarding whether Der p 2 binds to Toll-like receptor ...
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Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages
... Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages Shinae Kang, 1,2 Seung-Pyo Lee, 2 Kyung Eun Kim, 2,3 ...
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Gene-environment interaction between Toll-like receptor 4 and mold exposure in the development of atopic dermatitis in preschool children
... Purpose:Geneticfactorsandenvironmentalexposuresarerecognizedasimportantriskfactorsforatopicdermatitis(AD)inchildren. ...
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The Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein, a toll-like receptor 4 agonist, enhances dendritic cell-based cancer vaccine potency.
... Copyright ⓒ 2012 by the Korean Society for Biochemistry and Molecular Biology This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ...
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Electric Stimulation Hyperthermia Relieves Inflammation the Suppressor of Cytokine Signaling 3-Toll Like Receptor 4 Pathway in a Prostatitis Rat Model
... 3-toll like receptor 4 pathway This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ...
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제주지역 알레르기 환자의 Toll-like receptor 4 (TLR 4) 유전자의 다형성 =Toll-like receptor 4 (TLR) polymorphisms in allergic diseases patients in Jeju
... 1'LR 4 수용체로 인식되는 병원체 독소의 하나인 LPS 에 노출 된 천식 환자는 증송에 심해진다는 것이다 즉， π R4 자극이 기관지염증반응을 악화시킨다는 점이다 이는 천식환자에서 알레 르겐 놓도보다는 LPS 양과 천석증상과의 상관관계가 높다는 점과 내독소를 홉입하면 기관지 수축이 일어난다는 연구결과가 뒷받침 한다 이와 달리 소아에서는 내독소에 노출된 아이틀이 아토피성 천식에 ...
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제주지역 동맥경화성 뇌경색 환자의 Toll-like receptor 4(TLR 4) 유전자의 다형성 =Toll-like receptor 4 (TLR4) polymorphisms in atherothrombotic ischemic stroke patients in Jeju
... receplor 4，Polymorphisms l 서 론 뇌좋중은 성인 사망의 중요한 웬인이며 전 세계적으로 매년 1500 만 영 정도의 뇌졸중 환자가 발생하여 그 충 1/3 은 사딩 J 하고 다른 1/3 은 심각한 장애자로 남게 된다 17) 뇌졸충은 많은 선진 국가뜰에서 암， 심장절환에 이어 3 위의 사망원인을 차지하고 있으며 대부분의 개발도상국가에서는 두 번째로 높은 사망원인 ...
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IL-17 and Toll-like Receptor 2 or Toll-like Receptor 4 Combined Engagement Upregulates RANKL and IL-6 in Human Rheumatoid Synovial Fibroblasts
... 면역조직염색화학법 4% 파라포름알데하이드에 고정된 각 활막(류마티 스관절염 환자, 골관절염 환자) 조직을 통상의 방법 대로 파라핀에 포매한 후 절편기를 이용하여 7 um 절편을 만들어 슬라이드에 붙인 후 헤마톡실린과 에 오진(hematoxylin-eosin) 염색을 하여 광학현미경으로 ...Ab를 4 o C에서 IL-6, IL-17 (R&D systems, ...
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Fusobacterium nucleatum GroEL signaling via Toll-like receptor 4 in human microvascular endothelial cells
... 2 Department of Oral Microbiology and Immunology, School of Dentistry, Seoul National University, Seoul, Korea 3 Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea (received August ...
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Toll-like receptor 4 mediated inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
... ５ endogenous LPS. LPS is absorbed from the gut and transported in the portal vein to the liver where it is rapidly cleared by the Kupffer cells. 3 Several lines of evidence indicate that LPS plays a role in chronic liver ...
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Toll like receptor 4 initiates an innate immune response to lipopolysacccharide in human conjunctival epithelial cells
... 방어선으로 작용한다. 침입한 병균에 대한 선천면역은 Toll-like receptor (TLRs)에 의해 시작되며, 그 중 TLR4은 그람 음성 세균의 구성 성분인 lipopolysaccharide (LPS)를 인지하여, 염증성 cytokine을 생성하 는 것으로 알려져 있다. 본 연구에서는 중층으로 배양된 결막상피세포에 ...
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Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein
... decoy receptor composed of hybrid LRR modules was used as a model repeat protein, and its interaction interface was rationally designed to increase the binding affinity for ...decoy receptor with MD2, we ...
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COVID-19 Patients Upregulate Toll-like Receptor 4-mediated Inflammatory Signaling That Mimics Bacterial SepsisInfectious Diseases, Microbiology & Parasitology
... deaths. 4 Most patients are asymptomatic or recover after mounting a self-limiting antiviral response with the development of neutralizing anti-viral antibodies and cell-mediated ...
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Study on the Immunomodulatory Effects of Ellagic Acid and their Mechanisms Related to Toll-like Receptor 4 in Macrophages
... TLR(toll like receptor)는 세포막에 존재하는 단백질 수용체로써 박테리아/바이러스의 특정 분자패턴을 인식하 거나 조직 손상시 유리되는 생체인자에 의하여 활성화되어 숙주의 방어반응에 중요한 역할을 하는 1차적 면역반응 (innate immue response)에 중요한 ...
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Clinical Significance of Toll-Like Receptor and Toll-Like Receptor BlockerJae Young Choi, Phil Hyun Song, Young Hwii Ko
... 15. Byrd-Leifer CA, Block EF, Takeda K, Akira S, Ding A. The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol. Eur J Immunol 2001;31:2448-57. 16. Rassa JC, Meyers JL, Zhang Y, Kudaravalli R, Ross SR. Murine ...
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