Toll-like receptor 2
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Toll-like Receptor 2 in Autoimmune Inflammation
... Keywords: Toll-like receptor; Toll-like receptor 2; Autoimmunity; Th17 Cells; T Lymphocytes, Regulatory; Experimental autoimmune encephalomyelitis INTRODUCTION Autoimmune ...
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Toll-like receptor 2 polymorphisms and nontuberculous mycobacterial lung diseases
... Medicine, 2 Seoul, Korea Received 21 January 2006/Returned for modification 14 April 2006/Accepted 17 May 2006 To investigate the occurrence of the Toll-like receptor 2 (TLR2) ...
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1. p. 159 Effect of Staphylea bumalda Leaf Extracts on Macrophage Activation through Toll-Like Receptor 2 and Toll-Like Receptor 4-dependent c-Jun N-terminal Kinase Activation
... 손호준 2 · 여주호 3 · 유주형 4 · 최민영 5 · 이재원 6 · 백정규 7 · 정진부 8† Effect of Staphylea bumalda Leaf Extracts on Macrophage Activation through Toll-Like Receptor 2 and Toll-Like ...
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Lack of the Association between Microsatellite Polymorphism in Toll-like Receptor 2 Gene and Development of COPD
... 만성폐쇄성폐질환 발생과의 연관성 결여 서울대학교 의과대학 내과학교실 및 폐 연구소 이희석, 이혜원, 김덕겸, 고동석, 박근민, 황용일, 이상민, 유철규, 김영환, 한성구, 심영수, 임재준 Lack of the Association between Microsatellite Polymorphism in Toll-like Receptor 2 ...
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Association of Toll-Like Receptor 2 Polymorphisms with Papillary Thyroid Cancer and Clinicopathologic Features in a Korean Population
... of Toll-Like Receptor 2 Polymorphisms with Papillary Thyroid Cancer and Clinicopathologic Features in a Korean Population Toll-like receptors (TLRs) single nucleotide ...
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Molecular Characterization and Expression Analysis of a Toll-like receptor 2/6 gene from Abalone (Haliotis discus hannai)
... 분리한 Toll- like receptor 2/6 유전자의 분자생물학적 특성 및 발현분석 용량 전사체 분석을 통해 TLR 2/6유전자의 일부 cDNA 염기 서열을 ...TLR 2/6 유전자는 1044 bp의 ORF 부위는 347개의 아미노산을 코딩하는 것으로 예측되었 다. 북방전복 TLR 2/6의 아미노산 ...
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FSL-1, a Toll-like Receptor 2/6 Agonist, Induces Expression of Interleukin-1α in the Presence of 27-hydroxycholesterol
... In the current study, we attempted to determine whether cholesterol or 27OHChol influences response to PAMP via PRRs. We selected FSL-1, a synthetic diacyl lipopeptide rec- ognized by Toll-like ...
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IL-17 and Toll-like Receptor 2 or Toll-like Receptor 4 Combined Engagement Upregulates RANKL and IL-6 in Human Rheumatoid Synovial Fibroblasts
... 7. 면역조직염색화학법 4% 파라포름알데하이드에 고정된 각 활막(류마티 스관절염 환자, 골관절염 환자) 조직을 통상의 방법 대로 파라핀에 포매한 후 절편기를 이용하여 7 um 절편을 만들어 슬라이드에 붙인 후 헤마톡실린과 에 오진(hematoxylin-eosin) 염색을 하여 광학현미경으로 관찰하였다. 사이토카인의 발현의 측정은 면역조직 화학염색방법으로 ABC (Vector ...
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Expression and Function of Toll-Like Receptor 2 and 4 in Human Melanocytes
... (지도교수: 강 희 영) Toll-like receptors (TLRs)는 선천성 면역 체계에서 중요한 역할을 하는 세포막에 존재하는 수용체이다. 피부에서는 미생물과 같은 외부 병원체에 의한 세균성 감염질환 외에 건선이나 여드름 등의 만성 염증성 질환의 병인에 TLR 이 중요한 역할을 할 것으로 생각되고 있으며 외부 병원체에 대한 1 차 방어벽인 각질형성세포에서 ...
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Induces Production of Thymic Stromal Lymphopoietin in Nasal Fibroblasts Through Toll-like Receptor 2
... This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, ...
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Barrier protection via Toll-like receptor 2 signaling in porcine intestinal epithelial cells damaged by deoxynivalnol
... GraphPad Software, San Diego, USA). Differences were considered significant if p < 0.05. Results DON disrupted intestinal barrier function in IPEC‑J2 cells It has been suggested that DON causes an increase in the ...
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Microglial toll-like receptor 2 contributes to kainic acid-induced glial activation and hippocampal neuronal cell death
... This possibility can be addressed in future studies using HMGB-1 KO mice. In addition to microglia activation, we observed macro- phage infiltration in KA-injected hippocampi. Because TLR2 is expressed on blood-borne ...
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Signaling pathways mediated by Toll-like Receptor 2 involved in the protection of oligodendrocytes from ischaemic cell death
... CNS like forming myelin and conduction by Na channel and node of Ranvier, remyelinate injured axon and reduced outcome of neurodegenerative diseases like white matter stroke, Alzheimer’s disease, and ...
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Expression of Toll-like Receptor 2 in Cultured Human Keratinocytes: The Effect of Bacterial Antigens, Cytokines and Calcium Concentration
... shown to play an important regulatory role in the cuta- neous inflammatory and immune response by producing a variety of cytokines. Keratinocyte-derived cytokines are critical to mobilizing leukocytes from the blood and ...
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Role of Extracellular Signal-Regulated Kinase 1/2 and Reactive Oxygen Species in Toll-Like Receptor 2-Mediated Dual-Specificity Phosphatase 4 Expression
... 한편, TLR 자극으로 TRAF6 복합체와 TAK1 복합체를 경 유한 신호는 IKK 복합체 대신 mitogen-Activated Protein Kinase (MAPK)를 활성화시키기도 한다. MAPK는 ERK1/2, p38 MAPK 및 JNK로 구분되는데, TLR 신호전달 과정에서 는 ERK1/2의 작용이 매우 두드러지게 나타나고 있다. 21 실제 로 Pam3CSK4에 의한 ...
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Toll-like receptor and silk sericin for tissue engineering
... Ajibade AA, Wang Q, Cui J, Zou J, Xia X, Wang M, et al. (2012) TAK1 negatively regulates NF-kappaB and p38 MAP kinase activation in Gr-1+CD11b+ neutrophils. Immunity 36, 43–54. Al-Halifa S, Zottig X, Babych M, Côté-Cyr ...
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Clinical Significance of Toll-Like Receptor and Toll-Like Receptor BlockerJae Young Choi, Phil Hyun Song, Young Hwii Ko
... mammalian Toll-like receptor (TLR) family, consisting of 13 members, plays an important role in innate recognition of specific patterns of microbial ...and Toll/interleukin-1 ...
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Lack of toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia
... of Toll signaling in innate immunity in flies was initially studied in the setting of antifungal responses to the pathogen Aspergillus fumigatus ...(1). Toll-like receptors (TLRs), with the exception ...
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제주지역 알레르기 환자의 Toll-like receptor 4 (TLR 4) 유전자의 다형성 =Toll-like receptor 4 (TLR) polymorphisms in allergic diseases patients in Jeju
... 4) 중합효소연쇄반응 t 별의 정제 1.5% gel 에 전기영통 후. TLR 4 유전자 산물 부위 (Fig U 의 젤을 X 띈 다음 새로운 tube 어 1 옮겨 DNA 을 추출 몇 분리하였다 DNA 추출 및 정저]는 Qiaex (Qiagen ，Germany) system 을 이용 하였다 Gel solubilizing solution QXl 50C μQ 을 gel 을 포함한 tube 에 첨가한 ...
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Toll-Like Receptor Ligands as Cancer Immunotherapeutics Shee Eun Lee
... Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) expressed in a wide spectrum of cell types that recognize distinctive ligands and subsequently activate adaptive immune responses. TLR ...
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