retinoic acid
Self-assembly of Retinoic Acid-conjugated Poly(Amino Acid)'s Derivative
... 2.3. 레티노익산이 접목된 PHEA (R-PHEA)합성 레티노익산을 DCC와 DMAP를 첨가하여 에스테르 결합과 촉매반응에 의해 PHEA에 접목시켰다. DCC, DMAP와 합성한 PHEA는 접목도에 맞게 지정된 양에 따라 용해시킨 후 , 25 ℃ 교반 하에 DMF에 첨가하였 으며 함량에 따라 레티노익산을 DMF에 완전히 용해 시켜 retinoic ...
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급성 전골수구백혈병에서 발생한 Retinoic Acid Syndrome 및 가성뇌종양
... 보여 retinoic acid syndrome에 의한 유리체출혈로 진단하였다. Retinoic acid syndrome에 대한 치료로 ATRA 약물 복용을 중지한 후, 덱 사메타손 정맥주사요법을 시행하였고 3일 후 백혈구 수가 정상으로 회복되어 , ATRA 용량을 반으로 줄여 약물 치료 를 다시 ...
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Upregulation of Nitric Oxide Synthase Activity by All-trans Retinoic Acid and 13-cis Retinoic Acid in Human Malignant Keratinocytes
... all-trans retinoic acid and 13-cis retinoic acid, on the activity of nitric oxide synthase (NOS) was evaluated in human malignant keratinocytes to examine the possible correlation of retinoids ...
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¢òzf Retinoic Acid~ ÛB Î"
... Inhibitory Effects of Retinoic Acid and Melanization of B16 Melanoma Cell by Epimedium koreanum Nakai and α-MSH Hyunja Chun,† Ilkwang Kim,* and Wonhong Woo† Professional Graduate School [r] ...
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Role of Retinoic Acid in the Gut Mucosal Immunity
... 하의 영유아이고, 6초에 1명씩 죽어가고 있다. 영양 부족은 감염증에 대한 저항성을 현저하게 저하시킨 다. 사망에 이르게 하는 감염증으로는‘지속성 설 사’가 첫째이고 다음으로 말라리아, 폐렴, 홍역 등 이다. 1986년에 Sommer 등은 비타민 A 보급이 설 사증상을 완화하여 어린이의 사망률을 저하시킨다 고 보고하였다. 이것은 다음 여러 연구자들에 의하 여 확인되었으며, 특히 5세 이하의 ...
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Epigenetic modification of retinoic acid-treated human embryonic stem cells
... 1 Department of Genetic Epidemiology, SNP Genetics, Inc., Seoul 153-803, 2 Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, 3 Department of Biological Sciences ...
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Reversible Symptomatic Myocarditis Induced by All-Trans Retinoic Acid Administration during Induction Treatment of Acute Promyelocytic Leukemia: Rare Cardiac Manifestation as a Retinoic Acid Syndrome
... All-trans retinoic acid (ATRA) followed by anthracycline-AraC chemotherapy has improved the outcome of acute promyelocytic ...observed. Retinoic acid syndrome (RAS) often occurs during the ...
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Endogenous retinoic acid mediates the early events in salamander limb regeneration
... of retinoic acid (RA) in salamander limb regeneration by blocking RA synthesis using disulfiram, an inhibitor of aldehyde dehydrogenase that oxidizes retinal to ...
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Control of Innate and Adaptive Lymphocytes by the RAR-Retinoic Acid Axis
... all-trans retinoic acid; CD, cluster of differentiation; DC, dendritic cell; dnRAR, dominant negative form of retinoic acid receptor; ERK, extracellular signal-regulated kinase; IFN, ...
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Combinational Treatment with Retinoic Acid Derivatives in Non-smallCell Lung Carcinoma In Vitro
... The first involves the participation of retinoid receptors in 4HPR-induced cellular events. This suggestion is supported by the observations that 4-HPR-induces RAR expression in various human carcinoma cell lines (13), ...
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Effect of Retinoic Acid in a Mouse Model of Allergic RhinitisHye-Lim Son,
... For the allergy mouse model, we followed our previous labora- tory studies. 17,18 Forty mice were sorted into 4 groups: the control (CON, n=10), Der f (AR, n=10), all-trans retinoic acid (ATRA, n=10), and ...
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Bis Is Involved in Glial Differentiation of P19 Cells Induced by Retinoic Acid
... 3 Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul 139-706, 4 Bioindustry Research Center, Korea Research Institute Bioscience and Biotechnology, Daejeon 305-806, ...
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Retinoic Acid Promotes Interleukin-4 Plasmid-Dimethylsulfoxide Topical Transdermal Delivery for Treatment of Psoriasis
... Zhong-Wen Chen*, Yin-Bing Zhang*, Xaing-Jun Chen, Xiao Liu, Zhen Wang, Xi-Kun Zhou, Ji Qiu, Nan-Nan Zhang, Xiu Teng, Yong-Qiu Mao, Chang-Yong Liu, Yu-Quan Wei, Jiong Li State Key Laboratory of Biotherapy, West China ...
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All- Retinoic Acid-induced Nephrotic-range Proteinuria in a Patient with Acute Promyelocytic Leukemia
... trans Retinoic Acid-induced Nephrotic-range Proteinuria in a Patient with Acute Promyelocytic Leukemia Seong Uk Lim, Se Ryeon Lee, Seong Rye Seo, Jae Sook Ahn, Yeo Kyeoung Kim, Deok Hwan Yang, Je Jung Lee ...
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ATRA (all-trans-retinoic acid) Syndrome in Acute Promyelocytic Leukemia: Clinical and Radiologic Findings
... 1987년에 retinoic acid receptor- alpha (RAR-a)가 염색체 17q21에 부호화 (encoding) 되어 있 고, 염색체 15번에 분점(breakpoint)이 있는 새로운 유전자가 있음이 밝혀졌다 (1, ...line)는 retinoic acid 투여하에 과립구로 분화되는 결과가 얻어졌고 HL-60 세포계에 풍부한 ...
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Protective Effect of All-Trans Retinoic Acid in Cisplatin-Induced Testicular Damage in Rats
... Purpose: To investigate the effects of all-trans retinoic acid (ATRA) in cisplatin (CP)-induced testicular damage in rats. Materials and Methods: Twenty-eight male Wistar rats were divided into four groups: ...
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Retinoic Acid-Related Orphan Receptor Alpha Reprograms Glucose Metabolism in Glutamine-Deficient Hepatoma Cells
... The retinoic acid receptor-related orphan receptor alpha (RORa) is a potent regulator of normal physio- logical functions, such as lipid and steroid metabo- ...
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치료 불응성 갑상선암에 대한 실험적 치료 약제: Histone Deacetylase Inhibitor, PPAR-gamma Agonist, Retinoic Acid
... 이 같은 필요성에 의해 최근에 유전자 치료와 같은 새로 운 치료법의 개발 및 새로운 약제의 개발에 대한 많은 연구 들이 저분화 암 및 미분화 암의 치료에 초점을 맞추어 진행 되고 있는데, 가능성 있는 새로운 치료 약제로 기대를 모으 고 있는 histone deacetylase inhibitor (HDAC-I), PPAR-γ agonist 및 retinoic acid ...
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All-trans Retinoic Acid Induces Expression and Secretion of Carboxypeptidase D in THP-1 Cells
... all-trans retinoic acid (ATRA), which is an active form of vitamin A and plays a critical regulatory role in both the innate and adaptive immunity, on CPD expression and secretion in human monocytic THP-1 ...
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Histone Methylation Regulates Retinoic Acid-induced <sub>Hoxc</sub> Gene Expression in F9 EC Cells
... 연구에서는 retinoic acid (RA)에 의해 유도된 Hoxc 유전 자의 순차적인 발현이 유전자 좌위의 특정 히스톤 변이에 의 해 일어나는 것인지를 밝히기 위해, F9 EC 세포에 날짜 별로 레티노산(RA)을 처리 한 후 RT-PCR, RNA-sequencing, ChIP assay 등의 분자생물․후성유전학적 기법을 이용하여 실험을 ...
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